Výsledky vyhledávání - "Stephan D. Stamatov"

O-Silylated C3-halohydrins as a novel class of protected building blocks for total, regio- and stereocontrolled synthesis of glycerolipid frameworks

Autor: Stephan D. Stamatov, Jacek Stawinski

Publikováno v: Org. Biomol. Chem.. 8:463-477

We propose O-silylated C3-halohydrins [1(3)-O-silyl-2-O-acyl-, 1,2(2,3)-O-bis(silyl)-, and 1(3)-O-acyl-2-O-silyl-3(1)-halo-sn-glycerides] as new chirons in the total synthesis of glycerolipid constructs. These are efficiently producible via opening o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c54cbe79d72efb77cdb0504f03c760c
https://doi.org/10.1039/b915533c

Zobrazit plný text záznamu

Regioselective and Stereospecific Halosilylating Cleavage of the Oxirane System of Glycidol Derivatives as an Efficient Strategy to C2-O-Functionalized C3-Vicinal Halohydrins

Autor: Jacek Stawinski, Stephan D. Stamatov

Publikováno v: European Journal of Organic Chemistry. 2008:2635-2643

Glycidyl esters and ethers undergo a regioselective andstereospecific opening of the oxirane ring upon treatment with trimethylsilyl halides (TMSX, X = Cl, Br, or I) in the presence of pyridine to produce the corresponding C2-O-trimethylsilyl-3(1)-ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0de3469125a6ecbc3b4765b4e3c7a446
https://doi.org/10.1002/ejoc.200800112

Zobrazit plný text záznamu

Direct Trifluoroacetylation Across a Trimethylsilyloxy System as a Stereospecific, Chemo- and Regioselective Approach to C3-Vicinal Halohydrins

Autor: Stephan D. Stamatov, Jacek Stawinski

Publikováno v: Synlett. 2007:0439-0442

Direct trifluoroacetylation across a trimethylsilyloxy system as a stereospecific, chemo- and regioselective approach to C3-vicinal halohydrins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e8c3557f28716955f8dc560d45b3bc6
https://doi.org/10.1055/s-2007-968031

Zobrazit plný text záznamu

Regioselective, Haloacylating Cleavage of an Oxirane System Mediated by Trifluoroacetic Anhydride/Trimethylsilyl Halides: An Efficient Entry to 2-Acyl-3-haloglycerols

Autor: Jacek Stawinski, Stephan D. Stamatov

Publikováno v: Synlett. 2006:2251-2255

Glycidyl esters in the presence of trifluoroacetic anhydride (TFAA) and trimethylsilyl halides (TMSX), undergo a regio-selective opening of the oxirane system with a subsequent migration of the acyl group to afford l-trifluoroacetyl-2-acyl-3-haloglyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3a5d678fbc7b9b4b9fe3c3bfa4e4f22
https://doi.org/10.1055/s-2006-948206

Zobrazit plný text záznamu

Regioselective and stereospecific cleavage of a terminal oxirane system: A novel synthetic approach to lipid mediator congeners—1,2(2,3)-diacyl-3(1)-halo-sn-glycerols

Autor: Jacek Stawinski, Stephan D. Stamatov

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 16:3388-3391

Glycidyl esters upon treatment with a mixture of carboxylic acid anhydride (CAA) and trimethylsilyl halide (TMSX) in the presence of tetra- n -butylammonium halide (Bu 4 NX, X = Cl, Br or I) undergo stereospecific and regioselective opening of the ox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce136a60b4e4f5a829869400c7999ba7
https://doi.org/10.1016/j.bmcl.2006.04.040

Zobrazit plný text záznamu

Efficient, highly regioselective, and stereospecific conversion of glycidol systems into C2-O-acylated vicinal halohydrins

Autor: Jacek Stawinski, Stephan D. Stamatov

Publikováno v: Tetrahedron Letters. 47:2543-2547

Glycidyl esters and ethers undergo a regioselective and stereospecific opening of the oxirane ring upon treatment in chloroform in the presence of pyridine with trimethylsilyl halide (TMSX, X = Cl, Br, or I) and a mixture of carboxylic acid (CA)–tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00a2c78d93443269cefd861e80bdf746
https://doi.org/10.1016/j.tetlet.2006.02.050

Zobrazit plný text záznamu

A direct transformation of O-silyl groups into O-trichloroacetates. A novel synthetic approach to protein kinase C ligands: 1-oleoyl-2-acetyl- and 1-hexadecyl-2-acetyl-sn-glycerols

Autor: Jacek Stawinski, Stephan D. Stamatov, Martin Kullberg

Publikováno v: Tetrahedron Letters. 46:6855-6859

A fluoride ion-promoted direct esterification of tert-butyldimethylsilyl- (TBDMS), or triisopropylsilyl (TIPS)-protected glycerol derivatives by means of trichloroacetic anhydride (TCAA), followed by removal of the trichloroacetyl transient protectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcb1a39f00cebb112c0f614fc12108f3
https://doi.org/10.1016/j.tetlet.2005.08.015

Zobrazit plný text záznamu

Regioselective opening of an oxirane system with trifluoroacetic anhydride. A general method for the synthesis of 2-monoacyl- and 1,3-symmetrical triacylglycerols

Autor: Stephan D. Stamatov, Jacek Stawinski

Publikováno v: Tetrahedron. 61:3659-3669

A trifluoroacetic anhydride-catalyzed opening of the oxirane system of glycidyl esters with a simultaneous migration of the acyl group provides a new, efficient entry to either 2-monoacylglycerols (2-MAG) or 1,3-symmetrical triglycerides (1,3-STG) as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70b8d9af3f282e483aa27a2bfb9c0a6e
https://doi.org/10.1016/j.tet.2005.02.034

Zobrazit plný text záznamu

Stereospecific and regioselective opening of an oxirane system. A new efficient entry to 1- or 3-monoacyl- and 1- or 3-monoalkyl-sn-glycerols

Autor: Jacek Stawinski, Stephan D. Stamatov

Publikováno v: Tetrahedron Letters. 46:1601-1605

Acyl or alkyl glycidols in the presence of trifluoroacetic anhydride (TFAA) and trifluoroacetate anions, undergo a regioselective and stereospecific opening of the oxirane system to produce the bis(trifluoroacetylated) derivatives, from which the cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02dd2f0fb2da9f7fefbed606dbb5c92b
https://doi.org/10.1016/j.tetlet.2005.01.093

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání