Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stephan Borghorst"'
Autor:
Georg Hempel, Anja Möricke, Stephan Borghorst, Joachim Gerss, Joachim Boos, Martin Schrappe, Dominik Schrey, Claudia Lanvers-Kaminsky
Publikováno v:
Pediatric Blood & Cancer. 54:952-958
Background On a voluntary basis therapeutic drug monitoring (TDM) was implemented in the ALL-BFM 2000 protocol for the three currently used asparaginase (ASNase) preparations (first line: native Escherichia coli ASNase; second line: pegylated ASNase
Autor:
Torsten Hoppe-Tichy, Christoph Lichtenstern, Stefan Hofer, Georg Hempel, Dominic Störzinger, Cornelius J. Busch, Stephan Borghorst, Markus A. Weigand
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:4468-4470
Abdominal surgery may affect intestinal absorption and the resulting levels of posaconazole in the blood. We measured plasma posaconazole levels in surgical intensive care unit (SICU) patients and tried to develop a predictive population pharmacokine
Autor:
Georg Hempel, Joachim Baumgart, Sabine Poppenborg, Dieter Franke, Thorsten König, Stephan Borghorst
Publikováno v:
Cancer chemotherapy and pharmacology. 74(2)
A new pegylated recombinant l-asparaginase (MC0609) was designed to improve pharmacokinetic characteristics and to further reduce immunogenicity in comparison with the currently marketed pegylated Escherichia coli l-asparaginase (pegaspargase, Oncasp
Publikováno v:
Pediatric hematology and oncology. 29(2)
The main aim of this analysis was to characterize the population pharmacokinetics of native Escherichia coli asparaginase (ASNase medac) in pediatric patients with previously untreated acute lymphoblastic leukemia. Secondary objective was to give fur
Autor:
Dominik, Schrey, Stephan, Borghorst, Claudia, Lanvers-Kaminsky, Georg, Hempel, Joachim, Gerss, Anja, Möricke, Martin, Schrappe, Joachim, Boos
Publikováno v:
Pediatric bloodcancer. 54(7)
On a voluntary basis therapeutic drug monitoring (TDM) was implemented in the ALL-BFM 2000 protocol for the three currently used asparaginase (ASNase) preparations (first line: native Escherichia coli ASNase; second line: pegylated ASNase and third l
Publikováno v:
Blood. 114:4803-4803
Abstract 4803 Introduction Native Escherichia Coli Asparaginase (ASNase) is an integral component in the therapy of acute lymphoblastic leukemia (ALL) and non-Hodgkin's Lymphoma (NHL). There is a great interindividual variability in treatment intensi