Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stephan A. Wacker"'
Publikováno v:
Current Genomics
The vertebrate A-P axis is a time axis. The head is made first and more and more posterior levels are made at later and later stages. This is different to the situation in most other animals, for example, in Drosophila. Central to this timing is Hox
Autor:
Cristobal Alvarado, Jörg Wiedenmann, Uwe Knippschild, Bernd Baumann, Karen Clauß, Horst Hameister, Götz von Wichert, Walter Knöchel, Tilman Borggrefe, Franz Oswald, Stephan A. Wacker, Gerd Ulrich Nienhaus
Publikováno v:
The EMBO Journal. 30:43-56
The evolutionarily conserved Notch signal transduction pathway regulates fundamental cellular processes during embryonic development and in the adult. Ligand binding induces presenilin-dependent cleavage of the receptor and a subsequent nuclear trans
Publikováno v:
Genomics. 95:250-255
Here, we review a recently discovered developmental mechanism. Anterior–posterior positional information for the vertebrate trunk is generated by sequential interactions between a timer in the early non-organiser mesoderm and the Spemann organiser.
Publikováno v:
Journal of Biological Chemistry. 285:8408-8421
Xenopus Oct25 is a POU family subclass V (POU-V) transcription factor with a distinct domain structure. To investigate the contribution of different domains to the function of Oct25, we have performed gain of function analyses. Deletions of the N- or
Publikováno v:
The Scientific World Journal, Vol 10, Pp 2207-2214 (2010)
The Scientific World Journal
The Scientific World Journal
We review a recently discovered developmental mechanism. Anterior-posterior positional information for the vertebrate trunk is generated by sequential interactions between a timer in the early nonorganizer mesoderm (NOM) and the Spemann organizer (SO
Autor:
Walter Knöchel, Stephan A. Wacker, Nabila Bardine, Brigitte Korte, Cornelia Donow, Antony J. Durston
Publikováno v:
Developmental Dynamics. 238:755-765
Hox genes are key players in defining positional information along the main body axis of vertebrate embryos. In Xenopus laevis, Hoxc6 was the first homeobox gene isolated. It encodes two isoforms. We analyzed in detail their spatial and temporal expr
Publikováno v:
Mechanisms of Development. 124:668-681
The formation of the vertebrate body axis during gastrulation strongly depends on a dorsal signaling centre, the Spemann organizer as it is called in amphibians. This organizer affects embryonic development by self-differentiation, regulation of morp
Autor:
Maximilian Schuff, Walter Knöchel, Antje Rossner, Cornelia Donow, Stephan A. Wacker, Susanne Gessert
Publikováno v:
Developmental Dynamics. 236:226-239
A functional knockdown of FoxN3, a member of subclass N of fork head/winged helix transcription factors in Xenopus laevis, leads to an abnormal formation of the jaw cartilage, absence or malformation of distinct cranial nerves, and reduced size of th
Autor:
Walter Knoechel, Gerda E. M. Lamers, Nabila Bardine, Cornelia Donow, Stephan A. Wacker, Antony J. Durston
Publikováno v:
Plos One
PLoS ONE, Vol 9, Iss 12, p e115208 (2014)
Plos One, 9(12), e0115208
PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e115208 (2014)
Plos One, 9(12), e0115208
PLoS ONE
Development and patterning of neural tissue in the vertebrate embryo involves a set of molecules and processes whose relationships are not fully understood. Classical embryology revealed a remarkable phenomenon known as vertical signalling, a gastrul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbab69cef8cd057e15abd6156747da1
https://doi.org/10.1371/journal.pone.0115208
https://doi.org/10.1371/journal.pone.0115208
Publikováno v:
Developmental Biology. 224:428-439
During Xenopus gastrulation, the internalizing mesendodermal cell mass is brought into contact with the multilayered blastocoel roof. The two tissues do not fuse, but remain separated by the cleft of Brachet. This maintenance of a stable interface is