Výsledky vyhledávání - "Stephan, René"

Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation

Autor: Georg Kollias, Vasileia Ismini Alexaki, Aaron Hoffmann, Markus Sperandio, Sergei A. Nedospasov, Johanna Kotrba, Thomas Fischer, Roland Immler, Anne Dudeck, Konstantinos Katsoulis-Dimitriou, Stephan René Jahn, Burkhart Schraven, Triantafyllos Chavakis, Jan Dudeck, Lorena Morton, Simon Winzer, Andreas Müller, Ildiko Rita Dunay, Martin Voss

Publikováno v: Immunity. 54(3)

Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we demonstrated that MC-derived tumor necrosis factor (TNF) was crucial for neutrophil extravasati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4cf972f59849e9f3e6dd6ad158bd07
https://pubmed.ncbi.nlm.nih.gov/33542498

Zobrazit plný text záznamu

Directional Mast Cell Degranulation of TNF into Blood Vessels Primes Neutrophil Extravasation

Autor: Roland Immler, Johanna Kotrba, Aaron Hoffmann, Sergei A. Nedospasov, Vasileia Ismini Alexaki, Andreas J. Mueller, Triantafyllos Chavakis, Lorena Morton, Simon Winzer, Markus Sperandio, Burkhart Schraven, Martin Voss, Ildiko Rita Dunay, Stephan René Jahn, Jan Dudeck, George Kollias, Thomas Fischer, Anne Dudeck

Publikováno v: SSRN Electronic Journal.

Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory insult, yet the molecular mechanism is still unknown. Here, we demonstrate that MC-derived TNF is crucial for neutrophil extravasation to sites of sterile ski

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bd321c90d64f3640ef92607b2158549
https://doi.org/10.2139/ssrn.3651507

Zobrazit plný text záznamu

Aislamiento de hongos causantes de infecciones micóticas superficiales en pacientes que asisten al Centro Nacional Dermatológico, 'Dr. Francisco José Gómez Urcuyo' diciembre 2018 –febrero 2019

Autor: González Rodríguez, Stephan René, Castro Navarro, María de los Ángeles

El estudio de las infecciones micóticas superficiales en el país, constituyen un tema trascendental, representan un alto índice de consultas médicas especialmente dermatológicas, debido a los daños estéticos que causan en los pacientes, estos,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3634::5ddc96798959121db836fae9487cf166
http://repositorio.unan.edu.ni/12040/1/100312.pdf

Zobrazit plný text záznamu

Vessel Network Architecture of Adult Human Islets Promotes Distinct Cell-Cell Interactions In Situ and Is Altered After Transplantation

Autor: Michele Solimena, Christian M. Cohrs, Chunguang Chen, Barbara Ludwig, Anja Steffen, Helena Chmelova, Stephan René Jahn, Stefan R. Bornstein, Stephan Speier, Eckhard Wolf, Jürgen Weitz, Andrea Bähr, Virginia Kamvissi, Julia Stertmann, Nikolai Klymiuk

Publikováno v: Endocrinology 158, 1-13 (2017)

slet cell hormone release is modulated by signals from endothelial and endocrine cells within the islet. However, models of intra-islet vascularization and paracrine cell signaling are mostly based on rodent pancreas. We here assessed for the first t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f081e248feac756355000cf86c67bf2
https://pubmed.ncbi.nlm.nih.gov/28324008

Zobrazit plný text záznamu

Alterations in β-cell calcium dynamics and efficacy outweigh islet mass adaptation in compensation of insulin resistance and prediabetes onset

Autor: Stephan René Jahn, Chunguang Chen, Ingo Uphues, Christian M. Cohrs, Helena Chmelova, Julie A. Chouinard, Stephan Speier, Julia Stertmann

Publikováno v: Diabetes 65, 2676-2685 (2016)

Emerging insulin resistance is normally compensated by increased insulin production of pancreatic β-cells, thereby maintaining normoglycemia. However, it is unclear whether this is achieved by adaption of β-cell function, mass, or both. Most import

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da70b1e5574aa263e5107ff2abe44717
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=48641

Zobrazit plný text záznamu