Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Stephan, Lange"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1211 (2024)
This comprehensive review explores the critical role of fatty acid (FA) metabolism in cardiac diseases, particularly heart failure (HF), and the implications for therapeutic strategies. The heart’s reliance on ATP, primarily sourced from mitochondr
Externí odkaz:
https://doaj.org/article/df4f8882f4b24820ac1a8cb011f0a5a1
Autor:
Matúš Soták, Meenu Rohini Rajan, Madison Clark, Matthew Harms, Alankrita Rani, Jamie D. Kraft, David Tandio, Tong Shen, Kamil Borkowski, Oliver Fiehn, John W. Newman, Marianne Quiding-Järbrink, Christina Biörserud, Peter Apelgren, Trude Staalesen, Carolina E. Hagberg, Jeremie Boucher, Ville Wallenius, Stephan Lange, Emma Börgeson
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104602- (2022)
Summary: Adipose tissue inflammation drives obesity-related cardiometabolic diseases. Enhancing endogenous resolution mechanisms through administration of lipoxin A4, a specialized pro-resolving lipid mediator, was shown to reduce adipose inflammatio
Externí odkaz:
https://doaj.org/article/c5ff3de8e19d47f9bfddeae805cb559f
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background It remains unclear to what extent the SARS-CoV-2/COVID-19 pandemic disrupted the normal progression of biomedical and medical science graduate programs and if there was a lasting impact on the quality and quantity of supervision o
Externí odkaz:
https://doaj.org/article/c17fee887e2f41978286e81340e6cdda
Autor:
Martin Cardaun, Wilhelm Schünemann, Ralf Schelenz, Alexander Kari, Stephan Lange, Christof Sigle
Publikováno v:
Forschung im Ingenieurwesen. 87:61-70
Due to recent advances in the field of broadband aerodynamic noise, tonalities of wind turbines (WT) are increasingly coming into focus in the wind industry. In this case, the structure is excited inside the drivetrain and the structure-borne sound p
Autor:
Enrico Pierantozzi, Péter Szentesi, Cecilia Paolini, Beatrix Dienes, János Fodor, Tamás Oláh, Barbara Colombini, Dilson E. Rassier, Egidio Maria Rubino, Stephan Lange, Daniela Rossi, László Csernoch, Maria Angela Bagni, Carlo Reggiani, Vincenzo Sorrentino
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1319 (2022)
Obscurin is a giant sarcomeric protein expressed in striated muscles known to establish several interactions with other proteins of the sarcomere, but also with proteins of the sarcoplasmic reticulum and costameres. Here, we report experiments aiming
Externí odkaz:
https://doaj.org/article/f90b0f4dbf77435398a6de274560e28c
Autor:
Sina Muster, William J. Riley, Kurt Roth, Moritz Langer, Fabio Cresto Aleina, Charles D. Koven, Stephan Lange, Annett Bartsch, Guido Grosse, Cathy J. Wilson, Benjamin M. Jones, Julia Boike
Publikováno v:
Frontiers in Earth Science, Vol 7 (2019)
Arctic lowlands are characterized by large numbers of small waterbodies, which are known to affect surface energy budgets and the global carbon cycle. Statistical analysis of their size distributions has been hindered by the shortage of observations
Externí odkaz:
https://doaj.org/article/a26564b3cd894ab99ac346e5a52a7145
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 5, p 984 (2021)
Three members of the obscurin protein family that contain tandem kinase domains with important signaling functions for cardiac and striated muscles are the giant protein obscurin, its obscurin-associated kinase splice isoform, and the striated muscle
Externí odkaz:
https://doaj.org/article/c0b8913de61e4cd4a9cb0a1916e6bd40
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7936 (2020)
The well-orchestrated turnover of proteins in cross-striated muscles is one of the fundamental processes required for muscle cell function and survival. Dysfunction of the intricate protein degradation machinery is often associated with development o
Externí odkaz:
https://doaj.org/article/4fe8059c53664a5f91d60fc1d0bcde6b
Autor:
Stephan Lange, Katja Gehmlich, Alexander S. Lun, Jordan Blondelle, Charlotte Hooper, Nancy D. Dalton, Erika A. Alvarez, Xiaoyu Zhang, Marie-Louise Bang, Yama A. Abassi, Cristobal G. dos Remedios, Kirk L. Peterson, Ju Chen, Elisabeth Ehler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Altered function of the muscle LIM protein (MLP) causes dilated cardiomyopathy in mice and humans. Lange et al. explain the molecular role of MLP in the heart by showing that it affects the signalling complex at the intercalated discs of failing hear
Externí odkaz:
https://doaj.org/article/b664fe69f60e4479bfe0ab916f7779bf
Autor:
Elisabeth Ehler, Robbert van der Pijl, Farah Sheikh, Coen A.C. Ottenheijm, Stephan Lange, Andrea A. Domenighetti
Publikováno v:
Biophysical Reviews
Muscle specific signaling has been shown to originate from myofilaments and their associated cellular structures, including the sarcomeres, costameres or the cardiac intercalated disc. Two signaling hubs that play important biomechanical roles for ca