Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Stephan, Forchhammer"'
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Daniela Lenders, Irina Bonzheim, Matthias Hahn, Maximilian Gassenmaier, Valentin Aebischer, Andrea Forschner, Max Matthias Lenders, Lukas Flatz, Stephan Forchhammer
Publikováno v:
Diagnostics, Vol 14, Iss 15, p 1644 (2024)
Background: Next-generation sequencing (NGS) is the most commonly used method for determining BRAF mutational status in patients with advanced melanoma. Automated PCR-based methods, such as the IdyllaTM system, are increasingly used for mutation diag
Externí odkaz:
https://doaj.org/article/5df4d4ba72344af2a6d94052d7443e6f
Autor:
Alexandra Liebmann, Jakob Admard, Sorin Armeanu-Ebinger, Hannah Wild, Michael Abele, Axel Gschwind, Olga Seibel-Kelemen, Christian Seitz, Irina Bonzheim, Olaf Riess, German Demidov, Marc Sturm, Malou Schadeck, Michaela Pogoda, Ewa Bien, Malgorzata Krawczyk, Eva Jüttner, Thomas Mentzel, Maja Cesen, Elke Pfaff, Michal Kunc, Stephan Forchhammer, Andrea Forschner, Ulrike Leiter-Stöppke, Thomas K. Eigentler, Dominik T. Schneider, Christopher Schroeder, Stephan Ossowski, Ines B. Brecht
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104797- (2023)
Summary: Background: Genomic characterisation has led to an improved understanding of adult melanoma. However, the aetiology of melanoma in children is still unclear and identifying the correct diagnosis and therapeutic strategies remains challenging
Externí odkaz:
https://doaj.org/article/127dec53e6d3434d85e40f46cbf6798e
Autor:
Lucas Mix, Manuel Knoll, Max-Felix Häring, Wolfgang Andreas Bethge, Jan C. Schröder, Stephan Forchhammer, Patrick Krumm, Christian M. Schürch, Martin Schaller, Claudia Lengerke
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Thymic carcinomas are exceedingly rare and very aggressive malignancies of the anterior mediastinum. While thymomas exhibit a high association with paraneoplastic syndromes, these phenomena are a rarity in thymic carcinomas. In general, acanthotic sy
Externí odkaz:
https://doaj.org/article/379809a67b5c4a34ab01df8955ac9c81
Autor:
Eftychia Chatziioannou, Jana Roßner, Thazin New Aung, David L. Rimm, Heike Niessner, Ulrike Keim, Lina Maria Serna-Higuita, Irina Bonzheim, Luis Kuhn Cuellar, Dana Westphal, Julian Steininger, Friedegund Meier, Oltin Tiberiu Pop, Stephan Forchhammer, Lukas Flatz, Thomas Eigentler, Claus Garbe, Martin Röcken, Teresa Amaral, Tobias Sinnberg
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104644- (2023)
Summary: Background: Recent advances in digital pathology have enabled accurate and standardised enumeration of tumour-infiltrating lymphocytes (TILs). Here, we aim to evaluate TILs as a percentage electronic TIL score (eTILs) and investigate its pro
Externí odkaz:
https://doaj.org/article/35c191c0b266487cb0126f25360675a8
Autor:
Stephan Forchhammer, Sonja Grunewald, Matthias Möhrle, Gisela Metzler, Thomas Eigentler, Anne-Kristin Münch, Hanna Ogrzewalla
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Ex-vivo confocal laser scanning microscopy provides a rapid alternative to routine histological processing using haematoxylin and eosin-stained sections. Previous studies suggest high diagnostic accuracy in basal cell carcinoma. This study investigat
Externí odkaz:
https://doaj.org/article/a09340c8f70c4965847911a8acb91191
Autor:
Malte Roerden, Rainer Döffinger, Gabriela Barcenas-Morales, Stephan Forchhammer, Stefanie Döbele, Christoph P. Berg
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-5 (2020)
Abstract Background Severe and disseminated non-tuberculous mycobacterial (NTM) infections are frequently linked to a genetic predisposition but acquired defects of the interferon gamma (IFNγ) / interleukin 12 (IL-12) pathway need to be considered i
Externí odkaz:
https://doaj.org/article/e3e1b37d542a4f4585d3ff42baaba6be
Autor:
Thomas K Eigentler, Teresa Amaral, Benjamin Weide, Graham Pawelec, Tobias Sinnberg, Claus Garbe, Lukas Flatz, Friedegund Meier, Kilian Wistuba-Hamprecht, Alfred Königsrainer, Oltin T Pop, Jonas Bochem, Henning Zelba, Janine Spreuer, Andrea Gaissler, Karolin Thiel, Can Yurttas, Daniel Soffel, Stephan Forchhammer, Heike Niessner, Markus W Löffler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/ae54a7ec886d4fc992af361601f875fa
Autor:
Hanna Ogrzewalla, Matthias Möhrle, Gisela Metzler, Thomas Eigentler, Anne-Kristin Münch, Stephan Forchhammer
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 3030 (2022)
Background: Digitally stained ex vivo confocal laser scanning microscopy (CLSM) scans are a possible alternative to formalin-fixed and paraffin-embedded (FFPE) and hematoxylin-eosin (H&E) stained slides. This study explores the diagnostic accuracy of
Externí odkaz:
https://doaj.org/article/65882756a0dd40c4badd5207384c17e2
Autor:
Maximilian Gassenmaier, Erik Weber, Ulrike Leiter, Matthias Hahn, Stephan Forchhammer, Hans-Martin Häfner, Alexander Scheu, Claus Garbe, Saskia Schnabl
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 9, p adv00561 (2021)
Removal of the deep fascia is recommended in therapy for dermatofibrosarcoma protuberans, but its necessity in the context of micrographic surgery is unclear. A retrospective clinicopathological analysis of 48 patients with dermatofibrosarcoma protub
Externí odkaz:
https://doaj.org/article/f23383e15a3847c7956a06afe7282422