Prevalence and Implications of TERT Promoter Mutation in Uveal and Conjunctival Melanoma and in Benign and Premalignant Conjunctival Melanocytic Lesions

Autor: Anna E, Koopmans, Kimberley, Ober, Hendrikus J, Dubbink, Dion, Paridaens, Nicole C, Naus, Stephan, Belunek, Bart, Krist, Edward, Post, Ellen C, Zwarthoff, Annelies, de Klein, Robert M, Verdijk, Jolanda, Vaarwater

Publikováno v: Investigative Ophthalmology & Visual Science, 55(9), 6024-6030. Association for Research in Vision and Ophthalmology Inc.

Purpose Hot-spot mutations in the promoter region of telomerase reverse transcriptase (TERT promoter mutations) occur frequently in cutaneous and conjunctival melanoma and are exceedingly rare in uveal melanoma. No information is available on the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762eeae50cd7c17cc29e056814182b15
https://doi.org/10.1167/iovs.14-14901