Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stepan S, Surov"'
Autor:
Wojciech Jankowski, Stepan S. Surov, Nancy E. Hernandez, Atul Rawal, Marcos Battistel, Daron Freedberg, Mikhail V. Ovanesov, Zuben E. Sauna
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Direct oral anticoagulants (DOACs) targeting activated factor Xa (FXa) are used to prevent or treat thromboembolic disorders. DOACs reversibly bind to FXa and inhibit its enzymatic activity. However, DOAC treatment carries the risk of antico
Externí odkaz:
https://doaj.org/article/61c278e166c64672affea2a9f7d21b28
Autor:
Ivan D. Tarandovskiy, Stepan S. Surov, Leonid A. Parunov, Yideng Liang, Wojciech Jankowski, Zuben E. Sauna, Mikhail V. Ovanesov
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Thrombin generation (TG) and fibrin clot formation represent the central process of blood coagulation. Up to 95% of thrombin is considered to be generated after the clot is formed. However, this was not investigated in depth. In this study,
Externí odkaz:
https://doaj.org/article/dca2acebe37f4b8dbe886c06c41fd9bf
Autor:
Yideng Liang, Joseph W. Jackson, Samuel A. Woodle, Stepan S. Surov, Leonid A. Parunov, Dorothy E. Scott, Mark Weinstein, Timothy K. Lee, Mikhail V. Ovanesov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Abstract Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa
Externí odkaz:
https://doaj.org/article/ab2eec995bec476b91c3b022656c3222
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 944-945 (2020)
Externí odkaz:
https://doaj.org/article/b2f169bd185d433e85f9d7ad0aaab62e
Autor:
Yideng Liang, Leonid A. Parunov, Maria E Shea, Mikhail V Ovanesov, Stepan S Surov, Dorothy E. Scott, Timothy K Lee, Maitreyi Chattopadhyay
Publikováno v:
Nature Protocols. 16:3981-4003
Thrombin generation (TG) assays are used widely to investigate both diseases and drugs that impact thrombosis and bleeding. TG assays were also instrumental in the identification of thrombogenic impurities in immune globulin products, which were asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e943a833a9c492c283998a62fce4f47
https://doi.org/10.1038/s41596-021-00568-4
https://doi.org/10.1038/s41596-021-00568-4
Autor:
Joseph W Jackson, M J Weinstein, Dorothy E. Scott, Mikhail V Ovanesov, Leonid A. Parunov, Samuel A. Woodle, Timothy K Lee, Yideng Liang, Stepan S Surov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa‐like pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1c222c4217df1a21ef8507b1bf991d
https://doi.org/10.1002/rth2.12467
https://doi.org/10.1002/rth2.12467
Autor:
Vladimir N Kolyadko, Sofya V Lushchekina, Tatiana A Vuimo, Stepan S Surov, Ruzanna A Ovsepyan, Vera A Korneeva, Ivan I Vorobiev, Nadezhda A Orlova, Leonid Minakhin, Konstantin Kuznedelov, Konstantin V Severinov, Fazoil I Ataullakhanov, Mikhail A Panteleev
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144940 (2015)
Factor XIIa (fXIIa) is a serine protease that triggers the coagulation contact pathway and plays a role in thrombosis. Because it interferes with coagulation testing, the need to inhibit fXIIa exists in many cases. Infestin-4 (Inf4) is a Kazal-type i
Externí odkaz:
https://doaj.org/article/a3e33141cf504a309b6f154e7fb7c5c9
Characterization of protein unable to bind von Willebrand factor in recombinant factor VIII products
Autor:
Philip Olivares, John R Pettersson, Mikhail V Ovanesov, Stepan S Surov, Ekaterina S. Marakasova, Wells W. Wu, Rong-Fong Shen, Andrey G Sarafanov, Haarin Chun, Svetlana A Shestopal
Publikováno v:
Journal of thrombosis and haemostasis : JTHREFERENCES. 19(4)
Background Therapeutic products with coagulation factor VIII (FVIII) have a wide range of specific activities, implying presence of protein with altered structure. Previous studies showed that recombinant FVIII products (rFVIII) contain a fraction (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc12dd0a0e89dc1ca4754799fd8d2a2
https://pubmed.ncbi.nlm.nih.gov/33527662
https://pubmed.ncbi.nlm.nih.gov/33527662
Autor:
Leonid A, Parunov, Maria E, Shea, Yideng, Liang, Stepan S, Surov, Maitreyi, Chattopadhyay, Timothy K, Lee, Dorothy E, Scott, Mikhail V, Ovanesov
Publikováno v:
Nature protocols. 16(8)
Thrombin generation (TG) assays are used widely to investigate both diseases and drugs that impact thrombosis and bleeding. TG assays were also instrumental in the identification of thrombogenic impurities in immune globulin products, which were asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9435459e3d4d369123f10bcbb175b5f
https://pubmed.ncbi.nlm.nih.gov/34215864
https://pubmed.ncbi.nlm.nih.gov/34215864
Autor:
Yideng Liang, Mikhail V Ovanesov, Leonid A. Parunov, Maitreyi Chattopadhyay, Stepan S. Surov, Timothy K Lee
Publikováno v:
Haemophilia. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3620c14cf3aa3e4ff6af98b0564a5e5a
https://doi.org/10.1111/hae.14024
https://doi.org/10.1111/hae.14024