Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stepan Pilyo"'
Autor:
Volodymyr Zyabrev, Bohdan Demydchuk, Stepan Pilyo, Victor Zhirnov, Olexandr Liavynets, Volodymyr Brovarets
Publikováno v:
Current Chemistry Letters, Vol 13, Iss 3, Pp 557-568 (2024)
Novel 2,4-disulfonylsubstituted 5-aminothiazoles were synthesized and their anticancer activity was assessed at a high dose (10 μM) against NCI 60 cancer cell lines. Compounds 24 and 25 showed the antiproliferative activity with mean growth inhibiti
Externí odkaz:
https://doaj.org/article/0c15811b6a114b73a799e649ce588730
Autor:
Ivan Semenyuta, Diana Hodyna, Vasyl Kovalishyn, Bohdan Demydchuk, Maryna Kachaeva, Stepan Pilyo, Volodymyr Brovarets, Larysa Metelytsia
Publikováno v:
Artificial Intelligence Chemistry, Vol 1, Iss 2, Pp 100024- (2023)
Here we describe the results of QSAR analysis based on artificial neural networks, synthesis, activity evaluation and molecular docking of a number of 1,3-oxazole derivatives as anti-E. coli antibacterials. All developed QSAR models showed excellent
Externí odkaz:
https://doaj.org/article/b7b407cb8adc4b28a282928c5d6375d3
Autor:
Maryna Kachaeva, Stepan Pilyo, Sergiy Popilnichenko, Andrii Kornienko, Eduard Rusanov, Volodymyr Prokopenko, Vladimir Zyabrev, Volodymyr S. Brovarets
Publikováno v:
Current Chemistry Letters, Vol 7, Iss 4, Pp 101-110 (2018)
Reaction of methyl 2-aryl-5-(chlorosulfonyl)-1,3-oxazole-4-carboxylates with 1H-pyrazol-5-amines and 1H-1,2,4-triazol-5-amines proceeds with the participation of endocyclic aminoazole nitrogen atoms to yield products containing a primary amino group.
Externí odkaz:
https://doaj.org/article/0c7caff22a474872ba7bdfd3aa659e10
Autor:
Andrea Angeli, Victor Kartsev, Anthi Petrou, Mariana Pinteala, Volodymyr Brovarets, Sergii Slyvchuk, Stepan Pilyo, Athina Geronikaki, Claudiu T. Supuran
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5082 (2021)
Carbonic anhydrases (CAs, EC 4.2.1.1) catalyze the essential reaction of CO2 hydration in all living organisms, being actively involved in the regulation of a plethora of patho/physiological conditions. A series of chromene-based sulfonamides were sy
Externí odkaz:
https://doaj.org/article/eba3cbcb3b224bae8157d7af2ddddb8a
Autor:
Yevheniia Velihina, Raey Gesese, Victor Zhirnov, Oleksandr Kobzar, Benjamin Bui, Stepan Pilyo, Andriy Vovk, Hai-Ying Shen, Volodymyr Brovarets
Publikováno v:
RSC Medicinal Chemistry. 14:692-699
The prepared oxazolopyrimidine derivatives exhibited high anti-breast-cancer activity and ADK suppression, indicating their potential as candidates in the targeted search for new, highly effective antitumor drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce3e5fe7b42502a455021f022549ceb
https://doi.org/10.1039/d2md00377e
https://doi.org/10.1039/d2md00377e
Autor:
Vladimir Zyabrev, Stepan Pilyo, Bohdan Demydchuk, Maryna Kachaeva, Ivan Semenyuta, Victor Zhirnov, Yevheniia Velihina, Volodymyr Brovarets
Publikováno v:
ChemMedChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2947d2eb560fdd97cef609bbf8457fa
https://doi.org/10.1002/cmdc.202300161
https://doi.org/10.1002/cmdc.202300161