Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stepan Lenevich"'
Publikováno v:
JMIR Dermatology, Vol 6, p e49278 (2023)
BackgroundInadequate control of atopic dermatitis (AD) increases the frequency of exacerbations and reduces the quality of life. Mobile health apps provide information and communication technology and may increase treatment adherence and facilitate d
Externí odkaz:
https://doaj.org/article/e653ae09fcb54b3f820c129b7dfed894
Autor:
Stepan Lenevich, Mark D. Distefano
Publikováno v:
Analytical Biochemistry. 408:316-320
Phosphorylated compounds are ubiquitous in life. Given their central role, many such substrates and analogs have been prepared for subsequent evaluation. Prior to biological experiments, it is typically necessary to determine the concentration of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ecc09979d504b06d4e7816d0c1ad1c
https://doi.org/10.1016/j.ab.2010.08.030
https://doi.org/10.1016/j.ab.2010.08.030
Autor:
Stepan Lenevich, Charuta C. Palsuledesai, Mark D. Distefano, Amanda J. DeGraw, Jonathan K. Dozier, Mohammad Rashidian, Joshua D. Ochocki
Publikováno v:
Chemical Biology & Drug Design. 76:460-471
Protein prenyltransferases catalyze the attachment of C15 (farnesyl) and C20 (geranylgeranyl) groups to proteins at specific sequences localized at or near the C-termini of specific proteins. Determination of the specific protein prenyltransferase su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::814e8f9ddd88f4b70f04761592e0e9d3
https://doi.org/10.1111/j.1747-0285.2010.01037.x
https://doi.org/10.1111/j.1747-0285.2010.01037.x
Autor:
Marisa L. Hovlid, Corey Strickland, Joshua D. Ochocki, Alan Hruza, Fernando López-Gallego, Nicholas P. Labello, Mark D. Distefano, Claudia Schmidt-Dannert, Olivier Henry, Victor G. Young, Rebecca L. Edelstein, Stepan Lenevich, Amanda J. DeGraw, Trista Talbot
Publikováno v:
Chemical Biology & Drug Design. 75:51-67
Photoactive analogs of farnesyl diphosphate (FPP) are useful probes in studies of enzymes that employ this molecule as a substrate. Here, we describe the preparation and properties of two new FPP analogs that contain diazotrifluoropropanoyl photophor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467b05142dd622acf09deeea5227b013
https://doi.org/10.1111/j.1747-0285.2009.00914.x
https://doi.org/10.1111/j.1747-0285.2009.00914.x
Autor:
Tatyana A. Mastryukova, V. P. Morgalyuk, Stepan Lenevich, Boris F. Myasoedov, G. V. Pribylova, I. L. Odinets, Ivan G. Tananaev, Oleg I. Artyushin, Galina V. Myasoedova, Elena V. Sharova
Publikováno v:
Russian Chemical Bulletin. 53:2499-2507
An efficient method for the synthesis of secondary alkylamides of phosphorylacetic acids (APA) was proposed. The method involves amidation of ethyl phosphorylacetates with primary aliphatic amines. The scope of reaction was determined. Reactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948fc4a137872508164d0e23aca61ba2
https://doi.org/10.1007/s11172-005-0146-2
https://doi.org/10.1007/s11172-005-0146-2
Publikováno v:
Nature Communications
ATP-binding cassette (ABC) transporters comprise a superfamily of proteins, which actively transport a variety of compounds across cell membranes. Mammalian and most eukaryotic ABC transporters function as exporters, flipping or extruding substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c04d04eedf1da9a26ed60d808f512e
https://pubmed.ncbi.nlm.nih.gov/22735453
https://pubmed.ncbi.nlm.nih.gov/22735453
Autor:
Amanda J, DeGraw, Charuta, Palsuledesai, Joshua D, Ochocki, Jonathan K, Dozier, Stepan, Lenevich, Mohammad, Rashidian, Mark D, Distefano
Publikováno v:
Chemical biologydrug design. 76(6)
Protein prenyltransferases catalyze the attachment of C15 (farnesyl) and C20 (geranylgeranyl) groups to proteins at specific sequences localized at or near the C-termini of specific proteins. Determination of the specific protein prenyltransferase su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8da08a91e10b92265a8e15fd3df105ee
https://pubmed.ncbi.nlm.nih.gov/21040496
https://pubmed.ncbi.nlm.nih.gov/21040496
Publikováno v:
Understanding Biology Using Peptides ISBN: 9780387265698
Introduction Protein prenylation consists of the attachment of 15 (farnesyl) or 20 (geranylgeranyl) carbon isoprenoids to proteins via a thioether linkage. The prenyl groups originate from the corresponding allylic diphosphates and are attached to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459a71d043c5c725d0ed85c4e03531ea
https://doi.org/10.1007/978-0-387-26575-9_123
https://doi.org/10.1007/978-0-387-26575-9_123
Publikováno v:
Journal of the American Chemical Society. 129(18)
To obtain a transition state (TS) structure for an enzyme-catalyzed prenylation reaction, SN1 and SN2 model substitution reactions with dimethylallyl chloride were first studied. 13C Kinetic isotope effects (KIEs) for the model reactions were measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6730d18dc8b5c98836553df692db56
https://pubmed.ncbi.nlm.nih.gov/17439118
https://pubmed.ncbi.nlm.nih.gov/17439118
Autor:
Benjamin P. Duckworth, Mark D. Distefano, Emily C. Jenson, Stepan Lenevich, Juhua Xu, Simon J. Gruber, Cheng Min Tann, George Barany, Amanda J. DeGraw
Publikováno v:
Chemical biologydrug design. 68(2)
Protein farnesyltransferase (PFTase) catalyzes the attachment of a geranylazide moiety to a peptide substrate, N-dansyl-GCVIA. Because geranylazide is actually a mixture of isomeric, interconverting primary and secondary azides, incorporation of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5115daffddcd0a2445543006c1e12319
https://pubmed.ncbi.nlm.nih.gov/16999773
https://pubmed.ncbi.nlm.nih.gov/16999773