Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Stepan Jerabek"'
Autor:
Daniela Georgieva, Ning Wang, Angelo Taglialatela, Stepan Jerabek, Colleen R. Reczek, Pei Xin Lim, Julie Sung, Qian Du, Michiko Horiguchi, Maria Jasin, Alberto Ciccia, Richard Baer, Dieter Egli
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114006- (2024)
Summary: Reprogramming to pluripotency is associated with DNA damage and requires the functions of the BRCA1 tumor suppressor. Here, we leverage separation-of-function mutations in BRCA1/2 as well as the physical and/or genetic interactions between B
Externí odkaz:
https://doaj.org/article/44e405bad36b4df4b62d48f8744cbc42
Autor:
Tomas Kovarnik, Matsuo Hitoshi, Ales Kral, Stepan Jerabek, David Zemanek, Yoshiaki Kawase, Hiroyuki Omori, Toru Tanigaki, Jan Pudil, Alexandra Vodzinska, Marian Branny, Roman Stipal, Petr Kala, Jan Mrozek, Martin Porzer, Tomas Grezl, Kamil Novobilsky, Oscar Mendiz, Karel Kopriva, Martin Mates, Martin Chval, Zhi Chen, Pavel Martasek, Ales Linhart
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 9 (2022)
Background The FiGARO (FFR versus iFR in Assessment of Hemodynamic Lesion Significance, and an Explanation of Their Discrepancies) trial is a prospective registry searching for predictors of fractional flow reserve/instantaneous wave‐free ratio (FF
Externí odkaz:
https://doaj.org/article/6dc7dee83dd241f5b3f1b2e5df6d619e
Autor:
Tomas Kovarnik, Miroslav Navratil, Jan Belohlavek, Mikulas Mlcek, Martin Chval, Zhi Chen, Stepan Jerabek, Otomar Kittnar, Ales Linhart
Publikováno v:
Intensive Care Medicine Experimental, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Background We studied a novel approach for the evaluation and management of volemia: minimally invasive monitoring of respiratory blood flow variations in the superior vena cava (SVC). We performed an experiment with 10 crossbred (Landrace
Externí odkaz:
https://doaj.org/article/699dff6084a64bc29af62c736e2b2178
Autor:
Jan Pudil, Ales Kral, Tomas Kovarnik, J Mrozek, David Zemanek, Stepan Jerabek, Hitoshi Matsuo, Oscar Mendiz, Petr Kala, Yoshiaki Kawase, Martin Mates, Hiroyuki Omori, A Vodzinska, Marian Branny, Toru Tanigaki
Publikováno v:
European Heart Journal. 41
Background The trial collected prospective data from physiology measurements of borderline lesions in five Czech, one Japan and one Argentinian cathlabs. The main purposes were to analyze diagnostic agreement between FFR (fractional flow reserve) and
Autor:
Stepan Jerabek, Tomas Kovarnik
Publikováno v:
Acta Cardiologica. 74:9-16
The only indication for coronary revascularization is elimination of ischaemia. Invasive hemodynamic methods (fractional flow reserve - FFR and instantaneous wave-free ratio (iFR) are superior to coronary angiography in detection of lesions causing m
Autor:
Aleš Linhart, Ling Zhang, Hana Skalická, Zhi Chen, Jan Horak, Gabriela Dostálová, Ales Kral, Andreas Wahle, Milan Sonka, Tomas Kovarnik, Stepan Jerabek
Publikováno v:
Kardiologia Polska. 74:1485-1491
Background and aim: To study relationships between endothelial dysfunction (ED) and coronary atherosclerosis derived from intravascular ultrasound (IVUS) and virtual histology (VH). Methods: Endothelial dysfunction was examined by EndoPAT system (Ita
Autor:
Ales Kral, Hitoshi Matsuo, Toru Tanigaki, Jan Pudil, Yoshiaki Kawase, Marian Branny, Zhi Chen, Milan Sonka, Tomas Kovarnik, Kristyna Bayerova, David Zemanek, Martin Mates, Alexandra Vodzinska, Stepan Jerabek, Karel Kopriva, Hiroyuki Omori
Publikováno v:
Acta cardiologica. 75(4)
Background: We tested whether the level of endothelial dysfunction assessed by digital tonometry, and expressed as reactive hyperemia index (RHI), is related to occurrences of a discrepancy between...
Autor:
Stepan Jerabek
Publikováno v:
Science. 368:592-592
It is in society9s best interest to prevent existential catastrophes by reducing natural, anthropogenic, and future threats, argues Toby Ord in The Precipice. His goal is not merely to aggregate research findings, but to assign a quantitative estimat
Autor:
Martin Chvál, Otomar Kittnar, Miroslav Navratil, Jan Belohlavek, Tomas Kovarnik, Zhi Chen, Mikulas Mlcek, Aleš Linhart, Stepan Jerabek
Publikováno v:
Intensive Care Medicine Experimental
Intensive Care Medicine Experimental, Vol 6, Iss 1, Pp 1-13 (2018)
Intensive Care Medicine Experimental, Vol 6, Iss 1, Pp 1-13 (2018)
Background We studied a novel approach for the evaluation and management of volemia: minimally invasive monitoring of respiratory blood flow variations in the superior vena cava (SVC). We performed an experiment with 10 crossbred (Landrace × large w
Autor:
Xiaoxiao Yang, Vlad Cojocaru, Yanpu Chen, Caitlin M. MacCarthy, Sergiy Velychko, Ralf Jauch, Vikas Malik, Kee-Pyo Kim, Hans R. Schöler, Calista Kl Ng, Guangming Wu, Marcos J. Araúzo-Bravo, Stepan Jerabek, Daniel Esch
Publikováno v:
EMBO Reports
The transcription factor Oct4 is a core component of molecular cocktails inducing pluripotent stem cells (iPSCs), while other members of the POU family cannot replace Oct4 with comparable efficiency. Rather, group III POU factors such as Oct6 induce