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pro vyhledávání: '"Stepan G"'
Inhibition of Xanthine Oxidase by Pyrazolone Derivatives Bearing a 4-(Furan-2-yl)benzoic Acid Moiety
Autor:
Alona V. Beiko, Oleksandr L. Kobzar, Maryna V. Kachaeva, Stepan G. Pilyo, Vsevolod Yu. Tanchuk, Andriy I. Vovk
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 21, Iss 4, Pp 27-35 (2023)
The pyrazolone-based 4-(furan-2-yl)benzoic acids have been synthesized and studied as xanthine oxidase inhibitors. This enzyme is one of the therapeutic targets for the treatment of hyperuricemia and related diseases. The compounds studied have found
Externí odkaz:
https://doaj.org/article/c837628d2ff64610be2c10ef61c2a44b
Autor:
Konstantin V. Zhdanov, Aleksandr N. Kovalenko, Vadim S. Chirsky, Denis A. Gusev, Natalia A. Nalivkina, Vsevolod A. Zinserling, Stepan G. Grigoriev, Regina A. Khairutdinova, Artem N. Isakov, Valerian V. Sharabkhanov
Publikováno v:
Терапевтический архив, Vol 94, Iss 11, Pp 1252-1256 (2022)
Clinical characteristics and pathomorphological manifestations in 69 patients aged 18 to 86 years with a fatal outcome of the disease were examined in order to analyze the causes of severe course and high mortality of generalized forms meningococcal
Externí odkaz:
https://doaj.org/article/c8d98578ee8142f1b49f75011f57391f
Autor:
Rashit M. Hantemirov, Christophe Corona, Sébastien Guillet, Stepan G. Shiyatov, Markus Stoffel, Timothy J. Osborn, Thomas M. Melvin, Ludmila A. Gorlanova, Vladimir V. Kukarskih, Alexander Y. Surkov, Georg von Arx, Patrick Fonti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
A 7,638 yr summer temperature reconstruction based on subfossil trees buried in the Siberian Arctic shows that recent warming is unprecedented and interrupted a multi-millennial cooling trend.
Externí odkaz:
https://doaj.org/article/66c18adde0aa491e908edd8d330da868
Autor:
Nikolay N. Murashkin, Leyla S. Namazova-Baranova, Svetlana G. Makarova, Roman A. Ivanov, Stepan G. Grigorev, Dmitri V. Fedorov, Eduard T. Ambarchian, Roman V. Epishev, Alexander I. Materikin, Leonid A. Opryatin, Alena A. Savelova
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionEpidermal barrier dysfunction in children with atopic dermatitis can cause transcutaneous sensitization to allergens and allergic diseases. We evaluated the effectiveness of an early-intervention algorithm for atopic dermatitis treatment,
Externí odkaz:
https://doaj.org/article/b2b449050edb481f9c9a9aea6f116733
Autor:
Irina Yu. Pronina, Nikolay N. Murashkin, Svetlana G. Makarova, Elena L. Semikina, Dmitry S. Yasakov, Stepan G. Grigoriev
Publikováno v:
Вопросы современной педиатрии, Vol 20, Iss 5, Pp 407-412 (2021)
Background. Children with congenital epidermolysis bullosa (CEB) can have vitamin D deficiency due to its malabsorption in intestine and reduced synthesis in skin as these patients have restrictions on staying in the sun. However, the prevalence of v
Externí odkaz:
https://doaj.org/article/1b033a47b8a342ec8af1621ae2d69830
Autor:
Nikolay N. Murashkin, Svetlana G. Makarova, Stepan G. Grigorev, Dmitri V. Fedorov, Roman A. Ivanov, Eduard T. Ambarchian, Roman V. Epishev, Alexander I. Materikin, Leonid A. Opryatin, Alena A. Savelova
Publikováno v:
Вопросы современной педиатрии, Vol 19, Iss 6, Pp 538-544 (2020)
Background. Malformations in epidermal barrier in children with atopic dermatitis (AD) can cause transcutaneous sensitization with further development of allergic diseases that can worsen the AD course and significantly reduces patients’ quality of
Externí odkaz:
https://doaj.org/article/338b358bf0e647caacaf2e4da4d18e99
Publikováno v:
Mountain Research and Development, Vol 40, Iss 2, Pp R32-R40 (2020)
Woody vegetation at the upper limit of its growth is a sensitive indicator of climate change. The aim of this study is to provide an analysis of the centuries-old spatiotemporal dynamics of larch trees at the upper limit of their growth (mountain mas
Externí odkaz:
https://doaj.org/article/e6bb3293b5bc4fc3bb508c48dec48fb5
Autor:
Margaryan, Stepan G.
This is the latest in a series of articles aimed at exploring the relationship between the complexity classes of P and NP. In the previous papers, we have proved that the sat CNF problem is polynomially reduced to the problem of finding a special cov
Externí odkaz:
http://arxiv.org/abs/2310.19833
Autor:
Viktor A Reva, Jonathan J Morrison, Alexey V Denisov, Alexey B Seleznev, Gennady G Rodionov, Stepan G Grigoriev, Igor S Zheleznyak, Igor M Samokhvalov
Publikováno v:
Journal of Endovascular Resuscitation and Trauma Management, Vol 2, Iss 1 (2018)
Background: The standard approach to an occlusive vascular injury is open arterial reconstruction, although endovascular stenting is becoming more common, despite limited evidence. The aim of this study is to examine whether bare-metal stents can be
Externí odkaz:
https://doaj.org/article/3b4e2d9261dc42679af1a522215c66d4
Autor:
Margaryan, Stepan G.
This is the second in a series of articles aimed at exploring the relationship between the complexity classes of P and NP. The research in this article aims to find conditions of an algorithmic nature that are necessary and sufficient to transform an
Externí odkaz:
http://arxiv.org/abs/1910.10708