Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Stepan B. Melnyk"'
Autor:
Melissa E. Heard-Lipsmeyer, Iad Alhallak, Frank A. Simmen, Stepan B. Melnyk, Rosalia C. M. Simmen
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Endometriosis is a chronic, estrogen-dependent gynecologic disorder that affects reproductive-aged women and to a lesser extent, post-menopausal women on hormone therapy. The condition is associated with systemic and local immune dysfunctions. While
Externí odkaz:
https://doaj.org/article/7d31c90c98c74fb7b8390db863e82a14
Autor:
Sudip Banerjee, Stepan B. Melnyk, Kimberly J. Krager, Nukhet Aykin-Burns, Sandra S. McCullough, Laura P. James, Jack A. Hinson
Publikováno v:
Toxicology Reports, Vol 4, Iss , Pp 134-142 (2017)
The hepatotoxicity of acetaminophen (APAP) occurs by initial metabolism to N-acetyl-p-benzoquinone imine which depletes GSH and forms APAP-protein adducts. Subsequently, the reactive nitrogen species peroxynitrite is formed from nitric oxide (NO) and
Externí odkaz:
https://doaj.org/article/ea8551acea1042f8b335c8cacc3fbe9b
Autor:
Sudip Banerjee, Sumit K. Shah, Stepan B. Melnyk, Rupak Pathak, Martin Hauer-Jensen, Snehalata A. Pawar
Publikováno v:
Antioxidants, Vol 7, Iss 4, p 55 (2018)
Gamma-tocotrienol (GT3) confers protection against ionizing radiation (IR)-induced injury. However, the molecular targets that underlie the protective functions of GT3 are not yet known. We have reported that mice lacking CCAAT enhancer binding prote
Externí odkaz:
https://doaj.org/article/9f67bf1ad0184026ab24d82cedb1a262
Autor:
Adam R. Brown, Iad Alhallak, Rosalia C. M. Simmen, Stepan B. Melnyk, Melissa E. Heard-Lipsmeyer, Maria Theresa E. Montales, Daniel Habenicht, Trang T. Van, Frank A. Simmen
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1737
Obesity, oxidative stress, and inflammation are risk factors for hepatocellular carcinoma (HCC). We examined, in mice, the effects of Krüppel-like factor 9 (KLF9) knockout on: adiposity, hepatic and systemic oxidative stress, and hepatic expression