The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells.

Autor: Høeberg M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Transport Biology section, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark.; Sino-Danish Center for Education and Research (SDC), Aarhus University, Denmark., Noer JB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Vistesen MV; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Bartels A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Bech EM; Transport Biology section, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark., Nygård SB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Lademann U; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Stenvang J; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Liu S; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China., Fuglsang AT; Transport Biology section, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark., Brünner N; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Moreira JMA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Publikováno v: Molecular oncology [Mol Oncol] 2023 Aug; Vol. 17 (8), pp. 1595-1612. Date of Electronic Publication: 2023 Apr 28.

1641P ABCG transporter and SRPK1 kinase inhibition of chemotherapy resistance: A phase Ib clinical trial of safety and maximum tolerated dose for SCO-101 in combination with gemcitabine and nab-paclitaxel in inoperable pancreatic cancer

Autor: Ladekarl, M., Shim, S., Ettrich, T.J., Kestler, A., Pfeiffer, P., Tarpgaard, L.S., Reinacher-Schick, A., Kraeft, A-L., Stenvang, J., Zurlo, A., Lindland Roest, N.

Publikováno v: In Annals of Oncology October 2023 34 Supplement 2:S907-S907

Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Eremophila galeata Chinnock.

Autor: Petersen MJ; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Lund XL; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.; Centre de Biochimie Structurale (CBS), INSERM, CNRS, Université de Montpellier, 29 rue de Navacelles, 34090 Montpellier, France., Semple SJ; Quality Use of Medicines and Pharmacy Research Centre, Clinical and Health Sciences, University of South Australia, Adelaide, SA 5000, Australia., Buirchell B; Wise Owl Consulting, Como, WA 6152, Australia., Franzyk H; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Gajhede M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Kongstad KT; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Stenvang J; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Staerk D; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

Publikováno v: Biomolecules [Biomolecules] 2021 Oct 18; Vol. 11 (10). Date of Electronic Publication: 2021 Oct 18.

605TiP Targeting anti-cancer drug resistance in gastro-intestinal cancer: Inhibition of the SRPK1 kinase and degradation of the ABCG2 drug efflux pump

Autor: Ladekarl, M., Schou, J.H.V., Roest, N.L., Stenvang, J., Brünner, N., Vestlev, P.M.

Publikováno v: In Annals of Oncology September 2020 31 Supplement 4:S503-S504

Association analysis of gut microbiota with LDL-C metabolism and microbial pathogenicity in colorectal cancer patients.

Autor: Qin, Mingjian¹ (AUTHOR), Huang, Zigui¹ (AUTHOR), Huang, Yongqi¹ (AUTHOR), Huang, Xiaoliang¹ (AUTHOR), Chen, Chuanbin¹ (AUTHOR), Wu, Yongzhi¹ (AUTHOR), Wang, Zhen¹ (AUTHOR), He, Fuhai¹ (AUTHOR), Tang, Binzhe¹ (AUTHOR), Long, Chenyan¹ (AUTHOR), Mo, Xianwei¹ (AUTHOR) moxianwei888@163.com, Liu, Jungang¹ (AUTHOR) liujungang@gxmu.edu.cn, Tang, Weizhong¹ (AUTHOR) tangweizhong@gxmu.edu.cn

Publikováno v: Lipids in Health & Disease. 11/8/2024, Vol. 23 Issue 1, p1-20. 20p.