Fetal Zika virus inoculation in macaques revealed control of the fetal viral load during pregnancy.

Autor: Egloff, Charles^1,2 (AUTHOR), Fovet, Claire-Maëlle¹ (AUTHOR), Denis, Jessica³ (AUTHOR), Pascal, Quentin¹ (AUTHOR), Bossevot, Laetitia¹ (AUTHOR), Luccantoni, Sophie¹ (AUTHOR), Leonec, Marco¹ (AUTHOR), Dereuddre-Bosquet, Nathalie¹ (AUTHOR), Leparc-Goffart, Isabelle^4,5 (AUTHOR), Le Grand, Roger¹ (AUTHOR), Durand, Guillaume André^4,5 (AUTHOR), Badaut, Cyril^4,6 (AUTHOR), Picone, Olivier² (AUTHOR), Roques, Pierre^1,7 (AUTHOR) pierre.roques@cea.fr

Publikováno v: Virology Journal. 9/3/2024, Vol. 21 Issue 1, p1-15. 15p.

Age-dependent susceptibility to reovirus encephalitis in mice is influenced by maturation of the type-I interferon response.

Autor: Wu AG; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee., Pruijssers AJ; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee., Brown JJ; Department of Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee., Stencel-Baerenwald JE; Department of Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee., Sutherland DM; Department of Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee., Iskarpatyoti JA; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee., Dermody TS; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Publikováno v: Pediatric research [Pediatr Res] 2018 May; Vol. 83 (5), pp. 1057-1066. Date of Electronic Publication: 2018 Feb 21.

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain.

Autor: Adams Waldorf KM; Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA.; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden., Nelson BR; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Stencel-Baerenwald JE; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Studholme C; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Department of Bioengineering, University of Washington, Seattle, Washington, USA.; Department of Radiology, University of Washington, Seattle, Washington, USA., Kapur RP; Department of Pathology, University of Washington, Seattle, Washington, USA.; Department of Pathology, Seattle Children's Hospital, Seattle, Washington, USA., Armistead B; Department of Global Health, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Walker CL; Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington, USA., Merillat S; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Vornhagen J; Department of Global Health, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Tisoncik-Go J; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Baldessari A; Washington National Primate Research Center, Seattle, Washington, USA., Coleman M; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Dighe MK; Department of Radiology, University of Washington, Seattle, Washington, USA., Shaw DWW; Department of Radiology, University of Washington, Seattle, Washington, USA.; Department of Radiology, Seattle Children's Hospital, Seattle, Washington, USA., Roby JA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Santana-Ufret V; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Boldenow E; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Li J; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Gao X; Department of Bioengineering, University of Washington, Seattle, Washington, USA., Davis MA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Swanstrom JA; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Jensen K; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Widman DG; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Medwid JT; Department of Biology, New Mexico State University, Las Cruces, New Mexico, USA., Hanley KA; Department of Biology, New Mexico State University, Las Cruces, New Mexico, USA., Ogle J; Washington National Primate Research Center, Seattle, Washington, USA., Gough GM; Washington National Primate Research Center, Seattle, Washington, USA., Lee W; Washington National Primate Research Center, Seattle, Washington, USA., English C; Washington National Primate Research Center, Seattle, Washington, USA., Durning WM; Washington National Primate Research Center, Seattle, Washington, USA., Thiel J; Department of Radiology, University of Washington, Seattle, Washington, USA., Gatenby C; Department of Radiology, University of Washington, Seattle, Washington, USA., Dewey EC; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Fairgrieve MR; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Hodge RD; Allen Institute for Brain Science, Seattle, Washington, USA., Grant RF; Washington National Primate Research Center, Seattle, Washington, USA., Kuller L; Washington National Primate Research Center, Seattle, Washington, USA., Dobyns WB; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Pediatrics, University of Washington, Seattle, Washington, USA., Hevner RF; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Gale M Jr; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA.; Department of Immunology, University of Washington, Seattle, Washington, USA., Rajagopal L; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA.; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.

Publikováno v: Nature medicine [Nat Med] 2018 Mar; Vol. 24 (3), pp. 368-374. Date of Electronic Publication: 2018 Feb 05.

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.

Autor: Bouziat R; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Hinterleitner R; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Brown JJ; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA., Stencel-Baerenwald JE; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA., Ikizler M; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Mayassi T; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Meisel M; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Kim SM; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Discepolo V; Department of Medicine, University of Chicago, Chicago, IL, USA.; Department of Translational Medical Sciences, Section of Pediatrics, University of Naples Federico II, and CeInGe-Biotecnologie Avanzate, Naples, Italy., Pruijssers AJ; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Ernest JD; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Iskarpatyoti JA; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Costes LM; Department of Medicine, University of Chicago, Chicago, IL, USA.; Laboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center Rotterdam-Sophia Children's Hospital, Rotterdam, Netherlands., Lawrence I; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Palanski BA; Department of Chemistry, Stanford University, Stanford, CA, USA., Varma M; Division of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard University, Cambridge, MA, USA., Zurenski MA; Department of Medicine, University of Chicago, Chicago, IL, USA.; Committee on Immunology, University of Chicago, Chicago, IL, USA., Khomandiak S; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., McAllister N; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA., Aravamudhan P; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Boehme KW; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA., Hu F; Department of Medicine, University of Chicago, Chicago, IL, USA., Samsom JN; Laboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus University Medical Center Rotterdam-Sophia Children's Hospital, Rotterdam, Netherlands., Reinecker HC; Division of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kupfer SS; Department of Medicine, University of Chicago, Chicago, IL, USA.; University of Chicago Celiac Disease Center, University of Chicago, Chicago, IL, USA., Guandalini S; University of Chicago Celiac Disease Center, University of Chicago, Chicago, IL, USA.; Section of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Chicago, Chicago, IL, USA., Semrad CE; Department of Medicine, University of Chicago, Chicago, IL, USA.; University of Chicago Celiac Disease Center, University of Chicago, Chicago, IL, USA., Abadie V; Department of Microbiology, Infectiology, and Immunology, University of Montreal, and the Centre Hospitalier Universitaire (CHU) Sainte-Justine Research Center, Montreal, Quebec, Canada., Khosla C; Department of Chemistry, Stanford University, Stanford, CA, USA.; Department of Chemical Engineering, Stanford University, Stanford, CA, USA.; Stanford ChEM-H, Stanford University, Stanford, California, USA., Barreiro LB; Department of Genetics, CHU Sainte-Justine Research Center, Montreal, Quebec, Canada., Xavier RJ; Division of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard University, Cambridge, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ng A; Division of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard University, Cambridge, MA, USA., Dermody TS; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA. bjabri@bsd.uchicago.edu terence.dermody@chp.edu.; Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Jabri B; Department of Medicine, University of Chicago, Chicago, IL, USA. bjabri@bsd.uchicago.edu terence.dermody@chp.edu.; Committee on Immunology, University of Chicago, Chicago, IL, USA.; University of Chicago Celiac Disease Center, University of Chicago, Chicago, IL, USA.; Section of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Chicago, Chicago, IL, USA.; Department of Pathology, University of Chicago, Chicago, IL, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2017 Apr 07; Vol. 356 (6333), pp. 44-50.

Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate.

Autor: Adams Waldorf KM; Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA., Stencel-Baerenwald JE; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Kapur RP; Department of Pathology, University of Washington, Seattle, Washington, USA.; Department of Pathology, Seattle Children's Hospital, Seattle, Washington, USA., Studholme C; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Department of Bioengineering, University of Washington, Seattle, Washington, USA.; Department of Radiology, University of Washington, Seattle, Washington, USA., Boldenow E; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Vornhagen J; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA., Baldessari A; Washington National Primate Research Center, Seattle, Washington, USA., Dighe MK; Department of Radiology, University of Washington, Seattle, Washington, USA., Thiel J; Department of Radiology, University of Washington, Seattle, Washington, USA., Merillat S; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA., Armistead B; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA., Tisoncik-Go J; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Green RR; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Davis MA; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Dewey EC; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Fairgrieve MR; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Gatenby JC; Department of Radiology, University of Washington, Seattle, Washington, USA., Richards T; Department of Radiology, University of Washington, Seattle, Washington, USA., Garden GA; Department of Pathology, University of Washington, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA., Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, USA., Juul SE; Department of Pediatrics, University of Washington, Seattle, Washington, USA., Grant RF; Washington National Primate Research Center, Seattle, Washington, USA., Kuller L; Washington National Primate Research Center, Seattle, Washington, USA., Shaw DW; Department of Radiology, University of Washington, Seattle, Washington, USA.; Department of Radiology, Seattle Children's Hospital, Seattle, Washington, USA., Ogle J; Washington National Primate Research Center, Seattle, Washington, USA., Gough GM; Washington National Primate Research Center, Seattle, Washington, USA., Lee W; Washington National Primate Research Center, Seattle, Washington, USA., English C; Washington National Primate Research Center, Seattle, Washington, USA., Hevner RF; Department of Neurological Surgery, University of Washington, Seattle, Washington, USA.; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Dobyns WB; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, USA., Gale M Jr; Department of Immunology, University of Washington, Seattle, Washington, USA.; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Rajagopal L; Department of Pediatrics, University of Washington, Seattle, Washington, USA.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.; Department of Global Health, University of Washington, Seattle, Washington, USA.

Publikováno v: Nature medicine [Nat Med] 2016 Nov; Vol. 22 (11), pp. 1256-1259. Date of Electronic Publication: 2016 Sep 12.