Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Sten Magnus Aquilonius"'
Autor:
Sten-Magnus Aquilonius, Dag Nyholm
Publikováno v:
Upsala Journal of Medical Sciences, Vol 122, Iss 2, Pp 71-77 (2017)
This review will illustrate the process of moving from an idea through preclinical research and Galenic developments into clinical investigations and finally to approval by regulatory agencies within the European Union. The two new treatment strategi
Externí odkaz:
https://doaj.org/article/3cdbad13391d4ad9913524bb6298cfd3
Publikováno v:
Parkinson's Disease, Vol 2011 (2011)
During recent years, a syndrome of hypokinesia, dysarthria, dystonia, and postural impairment, related to intravenous use of a “designer” psychostimulant derived from pseudoephedrine using potassium permanganate as the oxidant, has been observed
Externí odkaz:
https://doaj.org/article/c4ce5751a21f42c4a9f1f79a7ad04f99
Autor:
Dag Nyholm, Sten-Magnus Aquilonius
Publikováno v:
Upsala Journal of Medical Sciences, Vol 122, Iss 2, Pp 71-77 (2017)
Upsala Journal of Medical Sciences
Upsala Journal of Medical Sciences
This review will illustrate the process of moving from an idea through preclinical research and Galenic developments into clinical investigations and finally to approval by regulatory agencies within the European Union. The two new treatment strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582937090b2faa209292735b4d53f5b3
https://doaj.org/article/3cdbad13391d4ad9913524bb6298cfd3
https://doaj.org/article/3cdbad13391d4ad9913524bb6298cfd3
Autor:
Radu Constantinescu, Jerker Westin, Sten-Magnus Aquilonius, Alexander Medvedev, Jack Spira, Mevludin Memedi, Fredrik Ohlsson, Håkan Askmark, Anders Ericsson, Filip Bergquist, Marina Senek, Dag Nyholm, Sara Lycke
Publikováno v:
European Journal of Clinical Pharmacology
Background Motor function assessments with rating scales in relation to the pharmacokinetics of levodopa may increase the understanding of how to individualize and fine-tune treatments. Objectives This study aimed to investigate the pharmacokinetic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a50b078b8b14338cf00a8d683366a6
http://europepmc.org/articles/PMC5384948
http://europepmc.org/articles/PMC5384948
Publikováno v:
Journal of Neurology and Neuromedicine. 1:25-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f4a8e41660724ac5c191bc7854de411
https://doi.org/10.29245/2572.942x/2016/4.1037
https://doi.org/10.29245/2572.942x/2016/4.1037
Autor:
M Ehrnebo, Jack Spira, Tommy Lewander, Tobias Bäckström, Dag Nyholm, Christer Nyström, C G Trolin, G Panagiotidis, Sten-Magnus Aquilonius
Publikováno v:
Acta Neurologica Scandinavica. 127:124-132
OBJECTIVES:An oral dispersible microtablet formulation of levodopa/carbidopa 5/1.25 mg (LC-5) was developed for individualized repeated dosing. The aim was to compare pharmacokinetic profiles of LC-5 and levodopa/carbidopa/entacapone (LCE).MATERIALS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2960375c9546e937a1f8aa6e1afc8
https://doi.org/10.1111/j.1600-0404.2012.01700.x
https://doi.org/10.1111/j.1600-0404.2012.01700.x
Autor:
Cecilia Gomes-Trolin, Tommy Lewander, Dag Nyholm, Sten-Magnus Aquilonius, Tobias Bäckström, Georgios Panagiotidis, Christer Nyström, Mats Ehrnebo
Publikováno v:
Clinical Neuropharmacology. 35:111-117
Objectives To compare bioavailability and pharmacokinetics of single doses of 3 different levodopa formulations given orally in healthy volunteers. Two marketed formulations, standard levodopa/carbidopa, 100/25 mg (LC-100), and dispersible levodopa/b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9184779d18f12dd95a056506e5591d0
https://doi.org/10.1097/wnf.0b013e31825645d1
https://doi.org/10.1097/wnf.0b013e31825645d1
Publikováno v:
Acta Pharmacologica et Toxicologica. 27:81-96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac61a6ef050595fee98b77e846649f61
https://doi.org/10.1111/j.1600-0773.1969.tb00496.x
https://doi.org/10.1111/j.1600-0773.1969.tb00496.x
Publikováno v:
Acta Pharmacologica et Toxicologica. 39:129-140
Following intravenous injection of a tracer dose of radioactive choline (3H–Ch), blood 3H–Ch was incorporated into parietal cortex at 1.2% per min. while the corresponding rate in the striatum was 6.4. It is suggested that this linear relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6489b53c9d554a2577a0ce2819e362c
https://doi.org/10.1111/j.1600-0773.1976.tb03163.x
https://doi.org/10.1111/j.1600-0773.1976.tb03163.x
Publikováno v:
Acta Neurologica Scandinavica. 64:47-53
Defined daily doses per day and 103 inhabitants (DDD/day/103 inh.) of the day different types of antiparkinson agents have been compared in the period 1975–1979 for Norway, Sweden, Denmark and Finland. A marked increase in the utilization of L-DOPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76980614cea7faffd5c5fa8083268a1
https://doi.org/10.1111/j.1600-0404.1981.tb04384.x
https://doi.org/10.1111/j.1600-0404.1981.tb04384.x