Zobrazeno 1 - 10
of 1 012
pro vyhledávání: '"Stem cell derived cardiomyocytes"'
Autor:
Dominic E. Fullenkamp, Alexander B. Willis, Jodi L. Curtin, Ansel P. Amaral, Kyle T. Dittloff, Sloane I. Harris, Ivana A. Chychula, Cory W. Holgren, Paul W. Burridge, Brenda Russell, Alexis R. Demonbreun, Elizabeth M. McNally
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/b52a5eadd7514af8ba2316e6c7190c6b
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
IntroductionPulsed Field Ablation (PFA) is a novel non-thermal method for cardiac ablation, relying on irreversible electroporation induced by high-energy pulsed electric fields (PEFs) to create localized lesions in the heart atria. A significant cha
Externí odkaz:
https://doaj.org/article/d2cea56cd73e427fbb2feaf73538409e
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/044918ed8a244aec9b7eb30c33b31c78
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9627 (2024)
Acute myocardial infarction (MI) is a sudden, severe cardiac ischemic event that results in the death of up to one billion cardiomyocytes (CMs) and subsequent decrease in cardiac function. Engineered cardiac tissues (ECTs) are a promising approach to
Externí odkaz:
https://doaj.org/article/737910db080242d7beff07b2eb519fed
Autor:
Chris Denning, Andrew P Holmes, Katja Gehmlich, Nguyen T N Vo, Paulus Kirchhof, Jonas Euchner, Amar J Azad, Max J Cumberland
Publikováno v:
F1000Research, Vol 12 (2024)
Animal models have proven integral to broadening our understanding of complex cardiac diseases but have been hampered by significant species-dependent differences in cellular physiology. Human-induced pluripotent stem cell-derived cardiomyocytes (hiP
Externí odkaz:
https://doaj.org/article/5188b66493974968b86ab2bed156276c
Autor:
Carlotta Ronchi, Camilla Galli, Gabriele Tullii, Camilla Marzuoli, Marta Mazzola, Marco Malferrari, Silvia Crasto, Stefania Rapino, Elisa Di Pasquale, Maria Rosa Antognazza
Publikováno v:
Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)
Abstract Optical stimulation in the red/near infrared range recently gained increasing interest, as a not‐invasive tool to control cardiac cell activity and repair in disease conditions. Translation of this approach to therapy is hampered by scarce
Externí odkaz:
https://doaj.org/article/8bb4ec847c0f4a9d9700bc789c285ac0
Autor:
Julian C. Bachmann, Jeppe E. Kirchhoff, Julia E. Napolitano, Steve Sorota, William M. Gordon, Nicole Feric, Roozbeh Aschar‐Sobbi, Juan Lv, Zhiyou Cao, Ken Coppieters, Giulia Borghetti, Michael Nyberg
Publikováno v:
Experimental Physiology, Vol 108, Iss 9, Pp 1172-1188 (2023)
Abstract The role of C‐type natriuretic peptide (CNP) in the regulation of cardiac function in humans remains to be established as previous investigations have been confined to animal model systems. Here, we used well‐characterized engineered car
Externí odkaz:
https://doaj.org/article/924e12c5295147d397da437fed3fabe0
Autor:
Yuki Tanaka, Shin Kadota, Jian Zhao, Hideki Kobayashi, Satomi Okano, Masaki Izumi, Yusuke Honda, Hajime Ichimura, Naoko Shiba, Takeshi Uemura, Yuko Wada, Shinichiro Chuma, Tsutomu Nakada, Shugo Tohyama, Keiichi Fukuda, Mitsuhiko Yamada, Tatsuichiro Seto, Koichiro Kuwahara, Yuji Shiba
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can be used to treat heart diseases; however, the optimal maturity of hiPSC-CMs for effective regenerative medicine remains unclear. We aimed to investigate th
Externí odkaz:
https://doaj.org/article/b753b6a2aa8c41179aa9cf4247289cee
Autor:
Shunit Neeman-Egozi, Ido Livneh, Irit Dolgopyat, Udi Nussinovitch, Helena Milman, Nadav Cohen, Binyamin Eisen, Aaron Ciechanover, Ofer Binah
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4932 (2024)
The ubiquitin–proteasome system (UPS) is an essential mechanism responsible for the selective degradation of substrate proteins via their conjugation with ubiquitin. Since cardiomyocytes have very limited self-renewal capacity, as they are prone to
Externí odkaz:
https://doaj.org/article/3b1ff9ecfa7d43ff81bb3fabd8fc1e91
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Background Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdevelope
Externí odkaz:
https://doaj.org/article/b736361c07044f5da99680857c9d2df7