Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Stem Cells and Regenerative Medicine"'
Peer reviewed: True
Mechanisms communicating changes in tissue stiffness and size are particularly relevant in the intestine because it is subject to constant mechanical stresses caused by peristalsis of its variable content. Using the Drosophil
Mechanisms communicating changes in tissue stiffness and size are particularly relevant in the intestine because it is subject to constant mechanical stresses caused by peristalsis of its variable content. Using the Drosophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c9145e1548c2a9310b8ae281298ab1
Autor:
Rute A. Tomaz, Ekaterini D. Zacharis, Fabian Bachinger, Annabelle Wurmser, Daniel Yamamoto, Sandra Petrus-Reurer, Carola M. Morell, Dominika Dziedzicka, Brandon T. Wesley, Imbisaat Geti, Charis-Patricia Segeritz, Miguel Cardoso de Brito, Mariya Chhatriwala, Daniel Ortmann, Kourosh Saeb-Parsy, Ludovic Vallier
Funder: UK Regenerative Medicine Platform
Funder: Wellcome Trust
Funder: Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge
Funder: Chan Zuckerberg Initiative
Production of large quantities of hepatocytes remain
Funder: Wellcome Trust
Funder: Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge
Funder: Chan Zuckerberg Initiative
Production of large quantities of hepatocytes remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e023f6edb4361b6326f9a402df618911
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The development of tissue fibrosis in the context of a wound-healing response to injury is common to many chronic diseases. Unregulated or persistent fibrogenesis may lead to structural and functional changes in organs that increase the risk of signi
Externí odkaz:
https://doaj.org/article/f02b5b198bcb4c3bac139c75b73f4818
Autor:
Akishige Hokugo, Yoichiro Shibuya, Hiroko Okawa, Takeru Kondo, Daniel Khalil, Lixin Wang, Yvonne Roca, Adam Clements, Hodaka Sasaki, Ella Berry, Ichiro Nishimura, Reza Jarrahy
Publikováno v:
eLife, Vol 11 (2022)
eLife
eLife
Attempts to minimize scarring remain among the most difficult challenges facing surgeons, despite the use of optimal wound closure techniques. Previously, we reported improved healing of dermal excisional wounds in circadian clock neuronal PAS domain
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Autor:
Tania Moody, Emilie Barruet, Edward C. Hsiao, Blanca M. Morales, Steven M. Garcia, Jake Wu, Jason H. Pomerantz, Stanley Tamaki
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Abnormalities in skeletal muscle repair can lead to poor function and complications such as scarring or heterotopic ossification (HO). Here, we use fibrodysplasia ossificans progressiva (FOP), a disease of progressive HO caused by ACVR1R206H (Activin
Autor:
Meiricris Tomaz da Silva, Kyle R. Bohnert, Raksha Bhat, Anirban Roy, Ashok Kumar, Takao Iwawaki
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Skeletal muscle regeneration is regulated by coordinated activation of multiple signaling pathways activated in both injured myofibers and satellite cells. The unfolded protein response (UPR) is a major mechanism that detects and alleviates protein-f
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
SummaryBrain development is regulated by conserved transcriptional programs across species, but little is known about divergent mechanisms that create species-specific characteristics. Among brain regions, the cerebellum is now recognized to contribu
Autor:
Chet Huan Oon, Kenneth E. Prehoda
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
The Par complex dynamically polarizes to the apical cortex of asymmetrically dividing Drosophila neuroblasts where it directs fate determinant segregation. Previously we showed that apically directed cortical movements that polarize the Par complex r
Autor:
Victor M. Darley-Usmar, Victor J. Thannickal, Vinayak Memula, Samuel R. Smith, Kyoko Kojima, Deepali Kurundkar, Jaroslaw W. Zmijewski, K.G. Dsouza, James A. Mobley, Gloria A. Benavides, Yong Wang, Jessy S. Deshane, Mohammad Rehan, Karen Bernard, Young-il Kim, Diptiman Chanda, Stijn De Langhe
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Multicellular organisms maintain structure and function of tissues/organs through emergent, self-organizing behavior. In this report, we demonstrate a critical role for lung mesenchymal stromal cell (L-MSC) aging in determining the capacity to form t