Zobrazeno 1 - 10
of 374
pro vyhledávání: '"Stem Cells/cytology"'
Autor:
Sherida M. de Leeuw, Aron W.T. Kirschner, Karina Lindner, Ruslan Rust, Vanessa Budny, Witold E. Wolski, Anne-Claude Gavin, Roger M. Nitsch, Christian Tackenberg
Publikováno v:
Stem Cell Reports
Stem cell reports, Vol. 17, No 1 (2022) pp. 110-126
Stem Cell Reports, 17 (1)
Stem cell reports, Vol. 17, No 1 (2022) pp. 110-126
Stem Cell Reports, 17 (1)
Summary The apolipoprotein E4 (APOE4) variant is the strongest genetic risk factor for Alzheimer disease (AD), while the APOE2 allele is protective. A major question is how different APOE genotypes affect the physiology of astrocytes, the main APOE-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b48530d239704416200f45d747af230
http://europepmc.org/articles/PMC8758949
http://europepmc.org/articles/PMC8758949
Autor:
Georges Lacaud, Pierre Savatier, Renaud Mevel, Syed Murtuza Baker, Irene Aksoy, Wen Hao Neo, Rahima Patel, Valerie Kouskoff, Magnus Rattray, Laura Fontenille, Roshana Thambyrajah, Nam Do Khoa, Muhammad Zaki Hidayatullah Fadlullah, Michael Lie-A-Ling
Publikováno v:
Fadlullah, M Z H, Neo, W H, Lie-a-ling, M, Thambyrajah, R, Patel, R, Mevel, R, Aksoy, I, Do Khoa, N, Savatier, P, Fontenille, L, Baker, S M, Rattray, M, Kouskoff, V & Lacaud, G 2022, ' Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE ', Blood, vol. 139, no. 3, pp. 343-356 . https://doi.org/10.1182/blood.2020007885, https://doi.org/10.1182/blood.2020007885
In vitro generation and expansion of hematopoietic stem cells (HSCs) holds great promise for the treatment of any ailment that relies on bone marrow or blood transplantation. To achieve this, it is essential to resolve the molecular and cellular path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915a20e90ef52787d2fbf9f575e922b5
https://doi.org/10.1182/blood.2020007885
https://doi.org/10.1182/blood.2020007885
Autor:
Vlad Cojocaru, Vikas Malik, Daisylyn Senna Tan, Mingxi Weng, Yogesh Srivastava, Lydia W.T. Cheung, Ralf Jauch, Guangming Wu, Asif Javed, Veeramohan Veerapandian
Publikováno v:
FEBS Journal, 287(1), 122-144. Wiley-Blackwell
The functional consequences of cancer-associated missense mutations are unclear for the majority of proteins. We have previously demonstrated that the activity of SOX and Pit-Oct-Unc (POU) family factors during pluripotency reprogramming can be switc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454c03752ac8a860e61b55539192c5c6
https://hdl.handle.net/20.500.11755/71f1888a-7614-4101-8c39-09d156b776c5
https://hdl.handle.net/20.500.11755/71f1888a-7614-4101-8c39-09d156b776c5
Autor:
Dinko Mitrečić, Valentina Hribljan, Denis Jagečić, Jasmina Isaković, Federica Lamberto, Alex Horánszky, Melinda Zana, Gabor Foldes, Barbara Zavan, Augustas Pivoriūnas, Salvador Martinez, Letizia Mazzini, Lidija Radenovic, Jelena Milasin, Juan Carlos Chachques, Leonora Buzanska, Min Suk Song, András Dinnyés
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 855, p 855 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
This article belongs to the Topic Emerging Translational Research in Neurological and Psychiatric Diseases: from In Vitro to In Vivo Models.
From the first success in cultivation of cells in vitro, it became clear that developing cell and/or tis
From the first success in cultivation of cells in vitro, it became clear that developing cell and/or tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a3d41895637532be7af543d1988123
https://urn.nsk.hr/urn:nbn:hr:105:463848
https://urn.nsk.hr/urn:nbn:hr:105:463848
Autor:
Rafael Romero, Sheila Cárcel, Judith Mazariegos, Coral Vivancos, Kerstin Bartscherer, Susanna Fraguas, Thileepan Sekaran, Jordi Ginés, Ma Dolores Molina, Francesc Cebrià
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Developmental Biology, 476, 53-67. Academic Press
Universidad de Barcelona
Developmental Biology, 476, 53-67. Academic Press
In developmental biology, the regulation of stem cell plasticity and differentiation remains an open question. CBP(CREB-binding protein)/p300 is a conserved gene family that functions as a transcriptional co-activator and plays important roles in a w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1f817d3a2e99c473b1939eed0511b1
https://doi.org/10.1016/j.ydbio.2021.02.008
https://doi.org/10.1016/j.ydbio.2021.02.008
Autor:
Alejandra Consejo, Neil Lagali, Sorcha Ní Dhubhghaill, Marie-José Tassignon, Carina Koppen, Joséphine Behaegel
Publikováno v:
Cornea
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Universitat Politècnica de Catalunya (UPC)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Universitat Politècnica de Catalunya (UPC)
Purpose: To assess the efficacy and safety of human leukocyte antigen-matched allogeneic cultivated limbal epithelial stem cell grafts in the treatment of aniridia-associated keratopathy (AAK). Methods: Six eyes of 6 patients with severe AAK received
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc742454561094838eb2ee686e2ca37
https://doi.org/10.1097/ico.0000000000002729
https://doi.org/10.1097/ico.0000000000002729
Publikováno v:
Nucleic Acids Research
Ji, Z, Li, Y, Liu, S X & Sharrocks, A 2021, ' The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation ', Nucleic acids research, vol. 49, no. 3, gkaa1281, pp. 1345-1363 . https://doi.org/10.1093/nar/gkaa1281
Ji, Z, Li, Y, Liu, S X & Sharrocks, A 2021, ' The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation ', Nucleic acids research, vol. 49, no. 3, gkaa1281, pp. 1345-1363 . https://doi.org/10.1093/nar/gkaa1281
Enhancers play important roles in controlling gene expression in a choreographed spatial and temporal manner during development. However, it is unclear how these regulatory regions are established during differentiation. Here we investigated the geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e96e56bc9b30f2609486706e78cc23
http://europepmc.org/articles/PMC7897486
http://europepmc.org/articles/PMC7897486
Publikováno v:
Cancer letters, vol. 484, pp. 50-64
Solid tumor growth triggers a dynamic host response, which recapitulates wound healing and defines the tumor microenvironment (TME). In addition to the action of the tumor cells themselves, the TME is maintained by a myriad of immune and stromal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d4c526f18540dbdc86599d3242ed3f
https://doi.org/10.1016/j.canlet.2020.05.005
https://doi.org/10.1016/j.canlet.2020.05.005