Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Stellate cell proliferation"'
Autor:
Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla, Sumona G. Lester, Getachew D. Belew, Sobia Zaidi, Raziyeh Abdolahipour, Abhishek P. Shrestha, Agnes O. Portuphy, Hannah L. Stankus, Raghd Abu Helal, Stefaan Verhulst, Sergio Duarte, Ali Zarrinpar, Leo A. van Grunsven, Scott L. Friedman, Robert F. Schwabe, Terry D. Hinds, Jr., Sivarajan Kumarasamy, Sonia M. Najjar
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102010- (2024)
Objectives: Hepatic CEACAM1 expression declines with advanced hepatic fibrosis stage in patients with metabolic dysfunction-associated steatohepatitis (MASH). Global and hepatocyte-specific deletions of Ceacam1 impair insulin clearance to cause hepat
Externí odkaz:
https://doaj.org/article/e69d9f2f8521498ea5cb94a3c6b0d26c
Akademický článek
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Autor:
Shao Shuaibo, Xiaohe Li, Ruotong Zhang, Hailong Li, Bai Jiakun, Zhun Bi, Liang Zhang, Wen Ning, Yiying Wei, Chunfeng Xie, Cheng Yang, Bowei Ma, Shanshan Zhang, Xiaoyang Ma, Honggang Zhou
Publikováno v:
Journal of Cellular and Molecular Medicine
Liver fibrosis is a disease caused by long‐term damage that is related to a number of factors. The current research on the treatment of liver fibrosis mainly focuses on the activation of hepatic stellate cell, in addition to protecting liver cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efaa7323faa2c66eea6131646c738d5
https://doi.org/10.1111/jcmm.15493
https://doi.org/10.1111/jcmm.15493
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 12 (2022)
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 12 (2022)
The aim of this study was to investigate the regulatory function of the non-coding microRNA-155 (miR-155) and suppressor of cytokine signaling 1 (SOCS1) in alcoholic hepatitis (AH) and its potential mechanism associated with the mitogen-activated pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51981f8cea848fba1102b77ba84023d5
http://europepmc.org/articles/PMC8803392
http://europepmc.org/articles/PMC8803392
Publikováno v:
Cell Cycle. 18:2239-2254
Alcoholic hepatitis (AH) is a severe condition developed in patients with underlying alcoholic liver disease. Epithelial cell adhesion molecule (EPCAM) plays a role in hepatitis. Therefore, the current study aimed to explore the effect of EPCAM and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33d4c5c700894a0688603eb654521e34
https://doi.org/10.1080/15384101.2019.1642067
https://doi.org/10.1080/15384101.2019.1642067
Publikováno v:
Journal of Cancer
Pancreatic cancer is a highly malignant disease that is associated with poor prognosis. One hallmark of pancreatic cancer is excessive desmoplasia, characterized by fibrous or connective tissue growth and altered tumor stroma. Pancreatic stellate cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7744ceab543e53839aa1c38f8c2576
https://doi.org/10.7150/jca.30235
https://doi.org/10.7150/jca.30235
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss, Pp 110586-(2020)
Sphingosine kinase 1 (SphK1) plays critical roles in the activation of hepatic stellate cells (HSCs) and liver fibrosis. Our previous study found that polydatin ameliorates chronic liver injury and fibrosis by inhibiting oxidative stress. However, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f574aa726293d42248b7d869d320ed
http://www.sciencedirect.com/science/article/pii/S0753332220307794
http://www.sciencedirect.com/science/article/pii/S0753332220307794
Publikováno v:
Annals of palliative medicine. 10(4)
BACKGROUND This study aims to investigate the impacts on the proliferation, inhibition, apoptosis, and cell cycle of hepatic stellate cells (HSC-T6) in rats by using traditional Chinese medicine (TCM) in serum. METHODS Twenty-seven rats were randomly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e8a658fd7b5cd11f4bb5b95bdd3b0e
https://pubmed.ncbi.nlm.nih.gov/33691445
https://pubmed.ncbi.nlm.nih.gov/33691445
Publikováno v:
Biochemical and biophysical research communications. 529(4)
Objective Hepatic stellate cells (HSC) activation and proliferation mediated the pathogenic development of hepatic fibrosis (HF). However, the underlying mechanisms remain poorly understood. In this study, we aimed to investigate the miR-29a-3p and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460726319a7d0849f6e0e05644ae1f9e
https://pubmed.ncbi.nlm.nih.gov/32819600
https://pubmed.ncbi.nlm.nih.gov/32819600
Autor:
Junjie Nan, Long Pan, Yifan Wang, Jun-Hao Zheng, Sarun Juengpanich, Jing Fang, Chenhao Tong, Zi-Yuan Wang, Qiuxia Gu
Publikováno v:
Ann Transl Med
Background: The mTOR pathway is vital for homeostasis, metabolism, cancer transplantation and regeneration in the liver. The aim of this study is to use a bibliometric method to reveal current research hotspots and promising future trends in mTOR sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c85b5c8271ffa7fc164b73439246a6
https://pubmed.ncbi.nlm.nih.gov/34532355
https://pubmed.ncbi.nlm.nih.gov/34532355