Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Stellanie Simmonds"'
Autor:
Angie Wadsworth, Lany Ruslim, Bhushan Samant, Dennis S. Hom, Linda Chen, Hongbing Zhang, Juri Y Fukuda, Mei-Chuan Ko, Anna Liao, Stellanie Simmonds, Karla P. Zeitz, Wes Zmolek, Raymond A. Chavez, Michael P. Bova, Balazs G. Szoke, Mark Dreyer, Albert W. Garofalo, Annika B. Malmberg, Eduardo R. Butelman, Ryan Holcomb, Jon E. Hawkinson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:619-630
The bradykinin B(1) receptor plays a critical role in chronic pain and inflammation, although efforts to demonstrate efficacy of receptor antagonists have been hampered by species-dependent potency differences, metabolic instability, and low oral exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd5c128d96318ca657dbc995c3d83a7
https://doi.org/10.1124/jpet.107.120352
https://doi.org/10.1124/jpet.107.120352
Autor:
Angie Wadsworth, Wenxian Mao, Stellanie Simmonds, Eric Peterson, Christopher Vandevert, F. Bong San Pablo, Ted Yednock, Ying-Zi Xu, David A. Quincy, Carlos Lorenzana, Andrei W. Konradi, Kassandra Inez Rossiter, Michael S. Dappen, Michael A. Pleiss, Frederique Bard, Elizabeth Messersmith, Brian Wipke, Caroline Garrido, Jenifer L. Smith, Christopher M. Semko, Jacek Jagodzinski, Lilibeth Dofiles
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(14)
Mitsunobu reactions were employed to link t-butyl esters of α4 integrin inhibitors at each of the termini of a three-arm, 40 kDa, branched PEG. Cleavage of the t-butyl esters using HCO2H provided easily isolated PEG derivatives, which are potent α4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcafb666735b97ff542c432529435a5
https://pubmed.ncbi.nlm.nih.gov/23743283
https://pubmed.ncbi.nlm.nih.gov/23743283