Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Stellan Sandler"'
Autor:
Zhengkang Luo, Charlotte Soläng, Mariela Mejia‐Cordova, Lina Thorvaldson, Martin Blixt, Stellan Sandler, Kailash Singh
Publikováno v:
FASEB BioAdvances, Vol 1, Iss 9, Pp 538-549 (2019)
Abstract In type 1 diabetes (T1D), the insulin‐producing β cells are destructed by immune mechanisms. It has been hypothesized that the very first immune response in T1D onset comes from innate immune cells, which further activates the adaptive im
Externí odkaz:
https://doaj.org/article/ca542103895b4ac4b1d72f4ff2bf056e
Autor:
Zhengkang Luo, Sara Lundin, Mariela Mejia-Cordova, Imane Hassani, Martin Blixt, Daisy Hjelmqvist, Joey Lau, Daniel Espes, Per-Ola Carlsson, Stellan Sandler, Kailash Singh
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12988 (2021)
The anti-inflammatory role of regulatory B cells (Breg cells) has been associated with IL-35 based on studies of experimental autoimmune uveitis and encephalitis. The role of Breg cells and IL-35+ Breg cells for type 1 diabetes (T1D) remains to be in
Externí odkaz:
https://doaj.org/article/54e51940bdee4665960904dd5d9ea963
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
Aim. To characterize the plasma levels of vascular endothelial growth factor (VEGF) in type 1 diabetes mellitus (T1D) and its relation to both present and historical metabolic control and microvascular complications. Methods. Plasma levels of VEGF an
Externí odkaz:
https://doaj.org/article/e78090740401476285a7db8b84dd07e0
Autor:
Olof Schreiber, Joel Petersson, Tomas Waldén, David Ahl, Stellan Sandler, Mia Phillipson, Lena Holm
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71843 (2013)
AIM: To investigate colonic mucus thickness in vivo in health and during experimental inflammatory bowel disease. METHODS: Colitis was induced with 5% DSS in drinking water for 8 days prior to experiment, when the descending colonic mucosa of anesthe
Externí odkaz:
https://doaj.org/article/0ccbbdfbe0f94d18b9b39b705e80780a
Publikováno v:
Cell Transplantation, Vol 15 (2006)
Proinflammatory cytokines play a major role in rejection of pancreatic islet allografts and in type 1 diabetes (T1D). In rodent islets, exposure to IL-1β alone or combined with IFN-γ induces expression of inducible nitric oxide synthase (iNOS). Inh
Externí odkaz:
https://doaj.org/article/ea234a88a4e042a48f6fc6739b4703ef
Autor:
Andreas Digre, Israel Vlodavsky, Lilach Gutter-Kapon, Stellan Sandler, Xiaomin Wang, Tahira Batool, Jin-Ping Li, Zhengkang Luo, Kailash Singh, Yuval Shaked, Gan-Lin Zhang, Ralph D. Sanderson, Neta Ilan
Publikováno v:
Matrix Biol
Heparanase, the sole heparan sulfate degrading endoglycosidase, regulates multiple biological activities that enhance tumor growth, angiogenesis and metastasis. Much of the impact of heparanase on tumor progression is related to its function in media
Autor:
Singh, Zhengkang Luo, Sara Lundin, Mariela Mejia-Cordova, Imane Hassani, Martin Blixt, Daisy Hjelmqvist, Joey Lau, Daniel Espes, Per-Ola Carlsson, Stellan Sandler, Kailash
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12988
The anti-inflammatory role of regulatory B cells (Breg cells) has been associated with IL-35 based on studies of experimental autoimmune uveitis and encephalitis. The role of Breg cells and IL-35+ Breg cells for type 1 diabetes (T1D) remains to be in
Publikováno v:
Perinatal Biochemistry ISBN: 9781003068624
Perinatal Biochemistry
Perinatal Biochemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ebd99ab649f5403f3210f5b0cf2664
https://doi.org/10.4324/9781003068624-8
https://doi.org/10.4324/9781003068624-8
Publikováno v:
Diabetes Care. 40:1090-1095
OBJECTIVE Many patients with long-standing type 1 diabetes have remaining functional β-cells. This study investigated immunological differences between patients with or without measurable remaining endogenous insulin production after ≥10 years dur
Publikováno v:
The Journal of Immunology. 204:237.25-237.25
In type 1 diabetes (T1D), the insulin producing β cells are damaged by unknown factors. Antigen presenting cells (APCs) are believed to present autoantigens to T cells, thus initiating the immune attacks to β cells. However, several types of APCs a