Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Stella Pearson"'
Autor:
Jeremy A. Herrera, Lewis A. Dingle, M. Angeles Monetero, Rajamiyer V. Venkateswaran, John F. Blaikley, Felice Granato, Stella Pearson, Craig Lawless, David J. Thornton
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Honeycombing is a histological pattern consistent with Usual Interstitial Pneumonia (UIP). Honeycombing refers to cystic airways located at sites of dense fibrosis with marked mucus accumulation. Utilizing laser capture microdissection coupl
Externí odkaz:
https://doaj.org/article/4bf7214b4b0e498ebb0d2bd16a5899df
Autor:
Stella Pearson, Rognvald Blance, Fei Yan, Ya-Ching Hsieh, Bethany Geary, Fabio M R Amaral, Tim C P Somervaille, Kristina Kirschner, Anthony D Whetton, Andrew Pierce
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286412 (2023)
Myelofibrosis is a myeloproliferative neoplasm (MPN) which typically results in reduced length and quality of life due to systemic symptoms and blood count changes arising from fibrotic changes in the bone marrow. While the JAK2 inhibitor ruxolitinib
Externí odkaz:
https://doaj.org/article/68dcd073260444a9951df4bb64585f57
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0266298 (2022)
Despite the big increase in precision medicine targeted therapies developing curative treatments for many cancers is still a major challenge due mainly to the development of drug resistance in cancer stem cells. The cancer stem cells are constantly e
Externí odkaz:
https://doaj.org/article/29d5104a52444955853afe0e14b6effc
Publikováno v:
HemaSphere, Vol 3, Iss 3 (2019)
Abstract. Myeloproliferative neoplasms (MPN) are clonal stem cell associated disorders inclusive of chronic myeloid leukemia (CML), Polycythaemia vera (PV), myelofibrosis (MF), and essential thrombocythemia (ET). They are characterized by increased p
Externí odkaz:
https://doaj.org/article/a6171f4d99754bf6b8fd7dd80fe99025
Publikováno v:
Stem Cell Reports, Vol 4, Iss 3, Pp 431-444 (2015)
The generation of in vivo repopulating hematopoietic cells from in vitro differentiating embryonic stem cells has remained a long-standing challenge. To date, hematopoietic engraftment has mostly been achieved through the enforced expression of ectop
Externí odkaz:
https://doaj.org/article/bd8334591c58438ab097d81012be8c73
Autor:
Jesuthas Ajendra, Stella Pearson, James E. Parkinson, Brian H.K. Chan, Henry J. McSorley, Tara E. Sutherland, Judith E. Allen
The early migratory phase of pulmonary helminth infections is characterized by tissue injury leading to the release of the alarmin IL-33 and subsequent induction of type 2 immune responses. We recently described a role for IL-17A, through regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba02b325a6844cd85dae1e5b4e115371
https://doi.org/10.1101/2022.11.03.515050
https://doi.org/10.1101/2022.11.03.515050
Autor:
Jeremy A. Herrera, Lewis A. Dingle, M. Angeles Montero, Rajamiyer V. Venkateswaran, John F. Blaikley, Felice Granato, Stella Pearson, Craig Lawless, David J. Thornton
Honeycombing (HC) is a histological pattern consistent with Usual Interstitial Pneumonia (UIP). HC refers to cystic airways (HC airways) located at sites of dense fibrosis with marked mucus accumulation. Utilizing laser capture microdissection couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37e5d49113c90ee12ed220bf6512a6c0
https://doi.org/10.1101/2022.09.03.506451
https://doi.org/10.1101/2022.09.03.506451
Autor:
James R Kelly, Stefan Meyer, Stella Pearson, Marion Schneider, Andrew Pierce, Roberto Paredes, Anthony D. Whetton, Hsiang Yin Teng, Tim C. P. Somervaille
Publikováno v:
Molecular Biology Reports
Aberrantly high expression of EVI1 in acute myeloid leukaemia (AML) is associated with poor prognosis. For targeted treatment of EVI1 overexpressing AML a more detailed understanding of aspects of spatiotemporal interaction dynamics of the EVI1 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb11907af4665220ee21667ded8b892
https://doi.org/10.1007/s11033-020-05829-1
https://doi.org/10.1007/s11033-020-05829-1
Autor:
Bruce D. Gelb, Stella Pearson, Baoqiang Guo, Anthony D. Whetton, Stefano Patassini, Narges Azadbakht, Sonia Mulero-Navarro, Stefan Meyer, Andrew Pierce, Christian Flotho, Julie A Brazzatti
Publikováno v:
Journal of Proteome Research
Juvenile myelomonocytic leukemia (JMML) is an aggressive myeloproliferative neoplasm of early childhood with a poor survival rate, thus there is a requirement for improved treatment strategies. Induced pluripotent stem cells offer the ability to mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370fc3a94983055c79af0659d065fc86
http://europepmc.org/articles/PMC6942217
http://europepmc.org/articles/PMC6942217
Publikováno v:
Parkinson, J, Pearson, S, Rückerl, D, Allen, J & Sutherland, T 2021, ' The magnitude of airway remodeling is not altered by distinct allergic inflammatory responses in BALB/c versus C57BL/6 mice but matrix composition differs ', Immunology and cell biology, vol. 99, no. 6, pp. 640-655 . https://doi.org/10.1111/imcb.12448
Allergic airway inflammation is heterogeneous with variability in immune phenotypes observed across asthmatic patients. Inflammation has been thought to directly contribute to airway remodeling in asthma, but clinical data suggest that neutralizing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ce7028fe5579000ce98771b14373a0
https://pubmed.ncbi.nlm.nih.gov/33587776
https://pubmed.ncbi.nlm.nih.gov/33587776