Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Stella P. Hartono"'
Autor:
Stella P. Hartono, Sheena Chatrath, Ozge N Aktas, Stephanie A Kubala, Korey Capozza, Ian A. Myles, Jonathan I. Silverberg, Alan Schwartz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disease that is associated with anxiety and depression. Few studies have addressed interventions for symptoms of anxiety and depression in this population. To determine the efficacy of in
Externí odkaz:
https://doaj.org/article/6b3b05eff44c4eca8108a7eb08d7e939
Autor:
Hongchang Zhao, Stella R Hartono, Kirtney Mae Flores de Vera, Zheyuan Yu, Krishni Satchi, Tracy Zhao, Roger Sciammas, Lionel Sanz, Frédéric Chédin, Jacqueline Barlow
Publikováno v:
eLife, Vol 11 (2022)
Class switch recombination generates distinct antibody isotypes critical to a robust adaptive immune system, and defects are associated with autoimmune disorders and lymphomagenesis. Transcription is required during class switch recombination to recr
Externí odkaz:
https://doaj.org/article/1cc4de19daa34fbdb2ea820c6df9b779
Autor:
Virginia Giuliani, Meredith A. Miller, Chiu-Yi Liu, Stella R. Hartono, Caleb A. Class, Christopher A. Bristow, Erika Suzuki, Lionel A. Sanz, Guang Gao, Jason P. Gay, Ningping Feng, Johnathon L. Rose, Hideo Tomihara, Joseph R. Daniele, Michael D. Peoples, Jennifer P. Bardenhagen, Mary K. Geck Do, Qing E. Chang, Bhavatarini Vangamudi, Christopher Vellano, Haoqiang Ying, Angela K. Deem, Kim-Anh Do, Giannicola Genovese, Joseph R. Marszalek, Jeffrey J. Kovacs, Michael Kim, Jason B. Fleming, Ernesto Guccione, Andrea Viale, Anirban Maitra, M. Emilia Di Francesco, Timothy A. Yap, Philip Jones, Giulio Draetta, Alessandro Carugo, Frederic Chedin, Timothy P. Heffernan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Arginine methylation by PRMTs is dysregulated in cancer. Here, the authors use functional genomics screens and identify PRMT1 as a vulnerability in pancreatic ductal adenocarcinoma, and further show that PRMT1 regulates RNA metabolism and coordinates
Externí odkaz:
https://doaj.org/article/a1a1a41f3dcc4a47a61b299fda338c49
Publikováno v:
eLife, Vol 9 (2020)
Displacement loops (D-loops) are signature intermediates formed during homologous recombination. Numerous factors regulate D-loop formation and disruption, thereby influencing crucial aspects of DNA repair, including donor choice and the possibility
Externí odkaz:
https://doaj.org/article/0b49950c133f4c2382f5323ebaf1c5a8
Autor:
Stefano G. Manzo, Stella R. Hartono, Lionel A. Sanz, Jessica Marinello, Sara De Biasi, Andrea Cossarizza, Giovanni Capranico, Frederic Chedin
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background Co-transcriptional R-loops are abundant non-B DNA structures in mammalian genomes. DNA Topoisomerase I (Top1) is often thought to regulate R-loop formation owing to its ability to resolve both positive and negative supercoils. How
Externí odkaz:
https://doaj.org/article/d230920f9e4044538f0d8cb487c07b20
Autor:
Shira Sagie, Shir Toubiana, Stella R. Hartono, Hagar Katzir, Aya Tzur-Gilat, Shany Havazelet, Claire Francastel, Guillaume Velasco, Frédéric Chédin, Sara Selig
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
ICF syndrome cells exhibit shortened telomeres and elevated levels of the noncoding RNA TERRA. Here the authors show this is associated with high levels of DNA damage, suggesting an increase in telomere dysfunction due to the formation of DNA: RNA hy
Externí odkaz:
https://doaj.org/article/a6ea7685f09c4013935240ad88a3e9f7
Autor:
Victoria M. Bedell, Alexander Meves, Stella P. Hartono, Priyabrata Mukherjee, Krishnendu Pal, Debabrata Mukhopadhyay, Luke H. Hoeppner, Rachel A. Kudgus, MaKayla R Serres, Stephen C. Ekker, Sk Kayum Alam, Madelyn O’Gorman, Stephanie R. Hall, Davis M. Seelig
Publikováno v:
Mayo Clin Proc
The negative health consequences of acute ultraviolet (UV) exposure are evident, with reports of 30,000 emergency room visits annually to treat the effects of sunburn in the United States alone. The acute effects of sunburn include erythema, edema, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac6fba4118e59da8f6401c19884167d
https://doi.org/10.1016/j.mayocp.2021.08.018
https://doi.org/10.1016/j.mayocp.2021.08.018
Autor:
Joseph P. Grande, Lilach O. Lerman, Stephen J. Textor, Karl A. Nath, Bruce E. Knudsen, Adeel S. Zubair, Stella P. Hartono
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 9, Pp 18640-18656 (2013)
Activation of the renin-angiotensin-aldosterone system plays a critical role in the development of chronic renal damage in patients with renovascular hypertension. Although angiotensin II (Ang II) promotes oxidative stress, inflammation, and fibrosis
Externí odkaz:
https://doaj.org/article/1d13de666ff64ea4b70867fb340a7804
Publikováno v:
eLife, Vol 4 (2015)
Aicardi–Goutières syndrome (AGS) is a severe childhood inflammatory disorder that shows clinical and genetic overlap with systemic lupus erythematosus (SLE). AGS is thought to arise from the accumulation of incompletely metabolized endogenous nucl
Externí odkaz:
https://doaj.org/article/dbafbfed16254558851d360809c83863
PurposeTo determine the utility of GLILD CT scoring system for assessment of GLILD in patients with CVID to avoid the need for lung biopsy. MethodsThe CT scoring system was developed as a consensus based on review of literature. Two radiologists, bli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d1f447ccf1cd5dfdf7f2298abfd799
https://doi.org/10.21203/rs.3.rs-406317/v1
https://doi.org/10.21203/rs.3.rs-406317/v1
