Early Immune Response Elicited by Different Trypanosoma cruzi Infective Stages

Autor: Brenda Celeste Gutierrez, Estela Lammel, Stella Maris González-Cappa, Carolina Verónica Poncini

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Trypanosoma cruzi is a protozoan parasite that affects millions of people in Latin America. Infection occurs by vectorial transmission or by transfusion or transplacental route. Immune events occurring immediately after the parasite entrance are poor

Externí odkaz: https://doaj.org/article/82b93a9165244a93b0df0c49ebcd4704

Molecular typing of

Autor: Silvia Analía, Repetto, Juan Quarroz, Braghini, Marikena Guadalupe, Risso, Lisana Belén, Argüello, Estela Inés, Batalla, Daniel Ricardo, Stecher, Mariela Fernanda, Sierra, Juan Miguel, Burgos, Marcelo Víctor, Radisic, Stella Maris, González Cappa, Paula, Ruybal

Publikováno v: Parasitology. 149(1)

This study analysed Strongyloides stercoralis genetic variability based on a 404 bp region of the cox1 gene from Latin-American samples in a clinical context including epidemiological, diagnosis and follow-up variables. A prospective, descriptive, ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2983f93601999596773a80b20e13dc8b
https://pubmed.ncbi.nlm.nih.gov/35184784

IL-10 participates in the expansion and functional activation of CD8+ T cells during acute infection with Trypanosoma cruzi

Autor: Catalina D. Alba Soto, Stella Maris González-Cappa, Estela I. Batalla, Agustina M. Pino-Martinez, Cristian Gabriel Miranda

Publikováno v: Journal of Leukocyte Biology. 105:163-175

IL-10 is a pleiotropic cytokine with immunoregulatory functions affecting various cell types. In a model of experimental infection with the protozoan Trypanosoma cruzi (T. cruzi), we found increased morbidity and lower parasite control in IL-10 defic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae74e85a51dff35ad8a38566430146b
https://doi.org/10.1002/jlb.3a0318-111rr

Trypanosoma cruzi Infection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1-Dependent Mechanisms

Autor: Stella Maris González-Cappa, Yvette van Kooyk, Gabriel A. Rabinovich, Steef Engels, Juan P. Cerliani, Marcela Alejandra Cucher, Carolina Verónica Poncini, Juan M. Ilarregui, Estela I. Batalla

Publikováno v: Poncini, C V, Ilarregui, J M, Batalla, E I, Engels, S, Cerliani, J P, Cucher, M A, van Kooyk, Y, Gonzalez-Cappa, S M & Rabinovich, G A 2015, ' Trypanosoma cruzi Infection Imparts a Regulatory Program in Dendritic Cells and T Cells via Galectin-1-Dependent Mechanisms ', Journal of Immunology, vol. 195, no. 7, pp. 3311-3324 . https://doi.org/10.4049/jimmunol.1403019
Journal of Immunology, 195(7), 3311-3324. American Association of Immunologists

Galectin-1 (Gal-1), an endogenous glycan-binding protein, is widely distributed at sites of inflammation and microbial invasion. Despite considerable progress regarding the immunoregulatory activity of this lectin, the role of endogenous Gal-1 during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c91d96ead0dc9005f5a23474e47c38
https://doi.org/10.4049/jimmunol.1403019

Dendritic cells devoid of IL-10 induce protective immunity against the protozoan parasite Trypanosoma cruzi

Autor: María Elisa Solana, Catalina D. Alba Soto, Stella Maris González-Cappa, Carolina Verónica Poncini, Valeria Tekiel, Agustina M. Pino-Martinez

Publikováno v: Vaccine. 28:7407-7413

In diverse models of microbial infections, protection is improved by immunization with dendritic cells (DC) loaded with whole pathogen lysate. However, pathogens that modulate DC function as a way to evade immunity may represent a challenge for these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee5d5c6fe43157e0e3cd2e1ddccf899
https://doi.org/10.1016/j.vaccine.2010.08.105