Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stella G. Hoft"'
Autor:
Alexander Piening, Emily Ebert, Carter Gottlieb, Niloufar Khojandi, Lindsey M. Kuehm, Stella G. Hoft, Kelly D. Pyles, Kyle S. McCommis, Richard J. DiPaolo, Stephen T. Ferris, Elise Alspach, Ryan M. Teague
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Obesity is a well-established risk factor for human cancer, yet the underlying mechanisms remain elusive. Immune dysfunction is commonly associated with obesity but whether compromised immune surveillance contributes to cancer susceptibility
Externí odkaz:
https://doaj.org/article/cd1f556956cf44109479901a6087aca1
Autor:
Spencer G. Willet, Nattapon Thanintorn, Helen McNeill, Sung-Ho Huh, David M. Ornitz, Won Jae Huh, Stella G. Hoft, Richard J. DiPaolo, Jason C. Mills
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 3, Pp 325-339 (2023)
Background & Aims: Acute and chronic gastric injury induces alterations in differentiation within the corpus of the stomach called pyloric metaplasia. Pyloric metaplasia is characterized by the death of parietal cells and reprogramming of mitotically
Externí odkaz:
https://doaj.org/article/cabec06a0a304c2999d88643e63e8b04
Autor:
Stella G. Hoft, Keith D. Kauffman, Shunsuke Sakai, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Daniel F. Hoft, Richard Herbert, Daniel L. Barber
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Alternative delivery routes of the current Mycobacterium tuberculosis (Mtb) vaccine, intradermally (ID) delivered BCG, may provide better protection against tuberculosis, and be more easily administered. Here, we use rhesus macaques to compa
Externí odkaz:
https://doaj.org/article/0ede394fe9264bd2be150bdaf50800d8
Autor:
Christine N. Noto, Stella G. Hoft, Kevin A. Bockerstett, Nicholas M. Jackson, Eric L. Ford, Luke S. Vest, Richard J. DiPaolo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 623-642 (2022)
Background & Aims: It is well established that chronic inflammation promotes gastric cancer–associated metaplasia, but little is known regarding the mechanisms by which immune cells and cytokines regulate metaplastic cellular changes. The goals of
Externí odkaz:
https://doaj.org/article/31ca8dd185f940d9ac0855d92d7ae0a8
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Single-cell RNA sequencing (scRNAseq) technology is still relatively new in the field of gastric cancer immunology but gaining significant traction. This technology now provides unprecedented insights into the intratumoral and intertumoral heterogene
Externí odkaz:
https://doaj.org/article/c829d707bb294522993d99e8ae7d8be4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Gastric cancer is a leading cause of mortality worldwide. The risk of developing gastric adenocarcinoma, which comprises >90% of gastric cancers, is multifactorial, but most associated with Helicobacter pylori infection. Autoimmune gastritis is a chr
Externí odkaz:
https://doaj.org/article/3e883cec97e94df4b1e97c505bddfef4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mast cells are an essential part of the immune system and are best known as important modulators of allergic and anaphylactic immune responses. Upon activation, mast cells release a multitude of inflammatory mediators with various effector functions
Externí odkaz:
https://doaj.org/article/c4fa2868a9394740aff8d5b142cf4ba8
Autor:
Tara Steffen, Mariah Hassert, Stella G. Hoft, E. Taylor Stone, Jianfeng Zhang, Elizabeth Geerling, Brian T. Grimberg, M. Scot Roberts, Amelia K. Pinto, James D. Brien
Publikováno v:
Vaccines, Vol 8, Iss 2, p 170 (2020)
Zika virus (ZIKV) is a significant public health concern due to the pathogen’s ability to be transmitted by either mosquito bite or sexual transmission, allowing spread to occur throughout the world. The potential consequences of ZIKV infection to
Externí odkaz:
https://doaj.org/article/826c2464d38c425eb9f11a46b072e5de
Autor:
Niloufar Khojandi, Louis Connelly, Alexander Piening, Stella G. Hoft, Michelle Pherson, Maureen J. Donlin, Richard J. DiPaolo, Ryan M. Teague
Publikováno v:
Cancer Immunol Immunother
Checkpoint blockade immunotherapy has become a first-line treatment option for cancer patients, with success in increasingly diverse cancer types. Still, many patients do not experience durable responses and the reasons for clinical success versus fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faed77b79c199288a81863602e9ea338
https://europepmc.org/articles/PMC10306114/
https://europepmc.org/articles/PMC10306114/
Autor:
Ahmad Rajeh, James D. Brien, Richard J. DiPaolo, Kyle J. Wolf, Courtney Schiebout, Stella G. Hoft, Tae-Hyuk Ahn, Amelia K. Pinto, Mariah Hassert
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008896 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Zika virus (ZIKV) is a significant global health threat due to its potential for rapid emergence and association with severe congenital malformations during infection in pregnancy. Despite the urgent need, accurate diagnosis of ZIKV infection is stil