Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Stella Elkabes"'
Autor:
Basavaraju G. Sanganahalli, Swathi Pavuluri, Jyothsna Chitturi, Peter Herman, Stella Elkabes, Robert Heary, Fahmeed Hyder, Sridhar S. Kannurpatti
Publikováno v:
Neurotrauma Reports, Vol 3, Iss 1, Pp 421-432 (2022)
Afferent nociceptive activity in the reorganizing spinal cord after SCI influences supraspinal regions to establish pain. Clinical evidence of poor motor functional recovery in SCI patients with pain, led us to hypothesize that sensory-motor integrat
Externí odkaz:
https://doaj.org/article/59a7f028b7444e238db3df22f47b6bd6
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background The recruitment of immune system cells into the central nervous system (CNS) has a profound effect on the outcomes of injury and disease. Glia-derived chemoattractants, including chemokines, play a pivotal role in this process. In
Externí odkaz:
https://doaj.org/article/9e859956fa4b4ed6aa4f6ba3dbf820d6
Autor:
Ersilia Mirabelli, Stella Elkabes
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Multiple sclerosis (MS) is a multifaceted, complex and chronic neurological disease that leads to motor, sensory and cognitive deficits. MS symptoms are unpredictable and exceedingly variable. Pain is a frequent symptom of MS and manifests as nocicep
Externí odkaz:
https://doaj.org/article/b27872b7cb3344ceb8330b962804c1b4
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background Neuropathic pain is often observed in individuals with multiple sclerosis (MS) and spinal cord injury (SCI) and is not adequately alleviated by current pharmacotherapies. A better understanding of underlying mechanisms could facil
Externí odkaz:
https://doaj.org/article/13667b0f221a4a0e8f40857b650fa16e
Autor:
Ying Li, Akshata A. Korgaonkar, Bogumila Swietek, Jianfeng Wang, Fatima S. Elgammal, Stella Elkabes, Vijayalakshmi Santhakumar
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 240-253 (2015)
Concussive brain injury results in neuronal degeneration, microglial activation and enhanced excitability in the hippocampal dentate gyrus, increasing the risk for epilepsy and memory dysfunction. Endogenous molecules released during injury can activ
Externí odkaz:
https://doaj.org/article/cedf6e5ad0be4f969199bcedd1a0d2f3
Autor:
Brian T. David, Ayomi Ratnayake, Matthew A. Amarante, Naresh Parvath Reddy, Wei Dong, Sujitha Sampath, Robert F. Heary, Stella Elkabes
Publikováno v:
Neurobiology of Disease, Vol 54, Iss , Pp 194-205 (2013)
Toll-like receptors (TLRs) are mediators of the innate immune response to exogenous pathogens. They have also been implicated in sterile inflammation associated with systemic injury and non-infectious diseases via binding of endogenous ligands, possi
Externí odkaz:
https://doaj.org/article/11c06239049d4b32a9ce6a96734314ac
Autor:
Peter Herman, Robert F. Heary, Fahmeed Hyder, Sridhar S. Kannurpatti, Jyothsna Chitturi, Stella Elkabes, Basavaraju G. Sanganahalli
Publikováno v:
J Neurotrauma
Because the presence of pain impedes motor recovery in individuals with spinal cord injury (SCI), it is necessary to understand their supraspinal substrates in translational animal models. Using functional magnetic resonance imaging (fMRI) in a rat m
Publikováno v:
Brain, Behavior, and Immunity
Highlights • Astroglial TLRs mediate host-defense and pathogen dissemination in CNS infections. • Astroglial TLRs help clearance of protein aggregates in neurodegenerative diseases. • Astroglial TLR signaling contributes to inflammation in CNS
Autor:
Deepak Subramanian, Ying Li, Akshata A. Korgaonkar, Vijayalakshmi Santhakumar, Sukwinder Singh, Alexandra Pallottie, Jenieve Guevarra, Dipika Sekhar, Kruthi Kella, Stella Elkabes, Bogumila Swietek
Publikováno v:
Annals of Neurology. 87:497-515
Objective Traumatic brain injury is a major risk factor for acquired epilepsies, and understanding the mechanisms underlying the early pathophysiology could yield viable therapeutic targets. Growing evidence indicates a role for inflammatory signalin
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background The recruitment of immune system cells into the central nervous system (CNS) has a profound effect on the outcomes of injury and disease. Glia-derived chemoattractants, including chemokines, play a pivotal role in this process. In addition