Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Stella E. Tsirka"'
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Major Depressive Disorder, or depression, has been extensively linked to dysregulated HPA axis function, chronic inflammation and cardiovascular diseases. While the former two have been studied in depth, the mechanistic connection between de
Externí odkaz:
https://doaj.org/article/212d2ad7d7d845c5b5f6f20c3c9edbb6
Autor:
Vikalpa Dammavalam, Deborah Rupert, Marcos Lanio, Zhaosheng Jin, Neil Nadkarni, Stella E. Tsirka, Sergio D. Bergese
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7772 (2024)
Ischemic stroke is a leading cause of disability worldwide. While much of post-stroke recovery is focused on physical rehabilitation, post-stroke dementia (PSD) is also a significant contributor to poor functional outcomes. Predictive tools to identi
Externí odkaz:
https://doaj.org/article/9c3a80bf573147f3864a25de8e0827df
Autor:
Hussein Kaddour, Marina McDew-White, Miguel M. Madeira, Malik A. Tranquille, Stella E. Tsirka, Mahesh Mohan, Chioma M. Okeoma
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Early invasion of the central nervous system (CNS) by human immunodeficiency virus (HIV) (Gray et al. in Brain Pathol 6:1–15, 1996; An et al. in Ann Neurol 40:611–6172, 1996), results in neuroinflammation, potentially through
Externí odkaz:
https://doaj.org/article/27e6be61b68346fa9bc0bd9849f13f70
Autor:
Nathaniel Hurley, Sailesh Srinivas, Justin Fang, Manli Sun, Simon Hong, Chia Te Chien, Alan Guo, Tamor A. Khan, Mingxing Li, Mircea Cotlet, Federico Moretti, Edith Bourret, Daniel Radin, Stella E. Tsirka, Maya Shelly, Stanislaus S. Wong
Publikováno v:
Royal Society Open Science, Vol 9, Iss 12 (2022)
We have synthesized several morphologies and crystal structures of MgWO4 using a one-pot hydrothermal method, producing not only monoclinic stars and large nanoparticles but also triclinic wool balls and sub-10 nm nanoparticles. Herein we describe th
Externí odkaz:
https://doaj.org/article/4265f93f53724b3987b7e153629041d0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In the past several years there has been a marked increase in our understanding of the pathophysiological hallmarks of glioblastoma development and progression, with specific respect to the contribution of the glioma tumor microenvironment to the rap
Externí odkaz:
https://doaj.org/article/ace76a51b6b049a1a1aae50918ddc5ac
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Here, the authors show that microglia depletion results in unstable wakefulness and altered levels of ceramide, influencing microglia in the mouse thalamic reticular nucleus (TRN). Stable wakefulness can be restored by activation of the TRN or inhibi
Externí odkaz:
https://doaj.org/article/85a4e328c23d4b989f9a8c639753deae
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Oligodendroglia play a critical role in CNS homeostasis by myelinating neuronal axons in their mature stages. Dysfunction in this lineage occurs when early stage OPCs are not able to differentiate to replace dying Mature Myelinating Oligodendrocytes.
Externí odkaz:
https://doaj.org/article/52de9f0f3c17498cbc3334197617693b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The efficacy of combining radiation therapy with immune checkpoint inhibitor blockade to treat brain tumors is currently the subject of multiple investigations and holds significant therapeutic promise. However, the long-term effects of this
Externí odkaz:
https://doaj.org/article/98222bebfc144d409e4e36bc7a0dc0ad
Autor:
Daniel P. Radin, Gregory Smith, Victoria Moushiaveshi, Alexandra Wolf, Robert Bases, Stella E. Tsirka
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma is the most common and aggressive primary brain tumor in adults. Median survival time remains at 16-20 months despite multimodal treatment with surgical resection, radiation, temozolomide and tumor-treating fields therapy. After genotoxi
Externí odkaz:
https://doaj.org/article/f03a5090f98046dbb590d8e5fb6dfa52
Autor:
Arman Fesharaki-Zadeh, Jeremy T. Miyauchi, Karrah St. Laurent-Arriot, Stella E. Tsirka, Peter J. Bergold
Publikováno v:
ASN Neuro, Vol 12 (2020)
Comorbid post-traumatic stress disorder with traumatic brain injury (TBI) produce more severe affective and cognitive deficits than PTSD or TBI alone. Both PTSD and TBI produce long-lasting neuroinflammation, which may be a key underlying mechanism o
Externí odkaz:
https://doaj.org/article/3d1a47d049bd4dafa8b4be079392776e