Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Stella Chai"'
Autor:
Xu Wu, Chun Yin, Jiang Ma, Stella Chai, Chunyuan Zhang, Sheng Yao, Onat Kadioglu, Thomas Efferth, Yang Ye, Kenneth Kin-Wah To, Ge Lin
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)
Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly
Externí odkaz:
https://doaj.org/article/5f23428dd85e423899251c55eb3bb20f
Autor:
Eunice Yuen Ting Lau, Jessica Lo, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Joyce Man Fong Lee, Johnson Kai Yu Ng, Stella Chai, Chi Ho Lin, Suk Ying Tsang, Stephanie Ma, Irene Oi Lin Ng, Terence Kin Wah Lee
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1175-1189 (2016)
Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesize
Externí odkaz:
https://doaj.org/article/3cdc6d5ccfb249248e8b45a87e42a838
Autor:
Hang Quach, Sung-Soo Yoon, Kihyun Kim, Ji Hyun Lee, Chandramouli Nagarajan, Phoebe Joy Ho, Michael S.Y. Low, Wei-Han Huang, Raymond Wong, Nina Liao, ChingFeng Lin, Matthew Britland, Julia Li, Stella Chai, Jin Seok Kim
Publikováno v:
Blood. 140:4264-4266
Autor:
Stephanie Ma, Alice Carrier, Nelson J Dusetti, Terence K Lee, Dan Xie, Yunfei Yuan, Nikki P Lee, Xin-Yuan Guan, Man Tong, Stella Chai, Lok-Hei Chan, Kai-Yu Ng
Effects of TP53INP1 shRNAs on migration and invasion was rescued by TP53INP1 overexpression, ruling out potential off-target effects of the knockdown shRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2971774098e2edb95159503b2486f573
https://doi.org/10.1158/0008-5472.22414349.v1
https://doi.org/10.1158/0008-5472.22414349.v1
Autor:
Stephanie Ma, Alice Carrier, Nelson J Dusetti, Terence K Lee, Dan Xie, Yunfei Yuan, Nikki P Lee, Xin-Yuan Guan, Man Tong, Stella Chai, Lok-Hei Chan, Kai-Yu Ng
Supplementary Tables 1-3 contains primer sequences for qPCR, luciferase reporter and ChIP assays. Figure Legends for Supplementary Figures 1-4 are also included.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974f10c764775ad3b4097d242b7e5b54
https://doi.org/10.1158/0008-5472.22414340
https://doi.org/10.1158/0008-5472.22414340
Autor:
Stephanie Ma, Alice Carrier, Nelson J Dusetti, Terence K Lee, Dan Xie, Yunfei Yuan, Nikki P Lee, Xin-Yuan Guan, Man Tong, Stella Chai, Lok-Hei Chan, Kai-Yu Ng
Identifying critical factors involved in the metastatic progression of hepatocellular carcinoma (HCC) may offer important therapeutic opportunities. Here, we report that the proapoptotic stress response factor TP53INP1 is often selectively downregula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9097f2c1784e6d221fae71ad5383bb
https://doi.org/10.1158/0008-5472.c.6508952.v1
https://doi.org/10.1158/0008-5472.c.6508952.v1
Autor:
Kenneth K.W. To, Jiang Ma, Stella Chai, Chunyuan Zhang, Chun Yin, Sheng Yao, Xu Wu, Thomas Efferth, Yang Ye, Onat Kadioglu, Ge Lin
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1885-1902 (2021)
Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly
Autor:
Sheng Yao, Chang-Qiang Ke, Liang Ma, Stella Chai, Yang Ye, Chunping Tang, Kenneth K.W. To, Ge Lin, Chun Yin
Publikováno v:
Phytochemistry. 126:47-58
A polyoxypregnane aglycone, 12β-O-acetyl-11α-O-isobutyryltenacigenin B, and four polyoxypregnane glycosides with a pachybionic acid ester moiety, 12β-O-acetyl-3-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandronyl)-11α-O-isobutyrylte
Autor:
Nikki P. Lee, Stella Chai, Stephanie Ma, Kwok Wah Chan, Mei Yuk Choi, Yan Ru Qin, Kin Tak Chan, Jin Na Chen, Sai Wah Tsao, Xin Yuan Guan, Tsun Ming Fung, KY Ng, Bin Li, Man Tong, Simon Law, Annie L. Cheung
Publikováno v:
The Journal of Pathology. 239:309-319
Oesophageal squamous cell carcinoma (ESCC) is the most common histological subtype of oesophageal cancer. The disease is particularly prevalent in southern China. The incidence of the disease is on the rise and its overall survival rate remains disma
Efficacy of annexin A3 blockade in sensitizing hepatocellular carcinoma to sorafenib and regorafenib
Autor:
Phillis W.F. Kau, Chung Mau Lo, Kwan Man, Man Tong, Stella Chai, Jin Ding, Steve T. Luk, Stephanie Ma, Terence K. Lee, Lei Zhou, Elly Sau-Wai Ngan, Noélia Che
Publikováno v:
Journal of hepatology. 69(4)
Background & Aims Advanced hepatocellular carcinoma (HCC) is a lethal malignancy with limited treatment options. Sorafenib is the only FDA-approved first-line targeted drug for advanced HCC, but its effect on patient survival is limited. Further, pat