Výsledky vyhledávání - "Stella C. Junqueira"

Post-translational modifications of Parkinson's disease-related proteins: Phosphorylation, SUMOylation and Ubiquitination

Autor: Kevin A. Wilkinson, Eduarda G.Z. Centeno, Stella C. Junqueira, Helena Cimarosti

Publikováno v: Junqueira, S C, Centeno, E G Z, Wilkinson, K & Cimarosti, H I 2019, ' Post-translational modifications of Parkinson's disease-related proteins : Phosphorylation, SUMOylation and Ubiquitination ', Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, vol. 1865, no. 8, pp. 2001-2007 . https://doi.org/10.1016/j.bbadis.2018.10.025

Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of dopaminergic neurons in the nigrostriatal pathway. The etiology of PD remains unclear and most cases are sporadic, however genetic mutations in more than 20 proteins ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c53981bbd9bf77bcd34cd6a49f9e47
https://doi.org/10.1016/j.bbadis.2018.10.025

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Inosine, an Endogenous Purine Nucleoside, Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis: a Role for A2A Adenosine Receptor

Autor: João B. Calixto, Stella C. Junqueira, Rafael C. Dutra, Mauricio P. Cunha, Igor dos Santos Coelho, Ana Lúcia S. Rodrigues, Adair R.S. Santos, Vicente Lieberknecht

Publikováno v: Molecular Neurobiology. 54:3271-3285

Multiple sclerosis (MS) is a T cell autoimmune, inflammatory, and demyelinating disease of the central nervous system (CNS). Currently available therapies have partially effective actions and numerous side reactions. Inosine, an endogenous purine nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285e9bea99e4d404330be7d26b67c3aa
https://doi.org/10.1007/s12035-016-9893-3

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Pharmacological evidence favouring the traditional use of the root bark of Condalia buxifolia Reissek in the relief of pain and inflammation in mice

Autor: Moacir Geraldo Pizzolatti, Graciela Maldaner, Dalila Venzke, Ana Paula Ruani, Stella C. Junqueira, Igor dos Santos Coelho, Ademir F. Morel, Róli Rodrigues Simões, Adair R.S. Santos, Eliane Maria Zanchet

Publikováno v: Journal of Ethnopharmacology. 175:370-377

Ethnopharmacological relevance The Condalia buxifolia root bark infusion is used in traditional medicine in Brazil as antipyretic, anti-inflammatory and against dysentery. This study was designed to investigate whether the methanolic extract of the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba8a36794b767fbfbe1c45412cf7fa6
https://doi.org/10.1016/j.jep.2015.09.028

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Oral treatment with essential oil of Hyptis spicigera Lam. (Lamiaceae) reduces acute pain and inflammation in mice: Potential interactions with transient receptor potential (TRP) ion channels

Autor: Felipe Meira de Faria, Glauce Regina Pigatto, Marcos José Salvador, Adair R.S. Santos, Róli Rodrigues Simões, Igor dos Santos Coelho, Stella C. Junqueira

Publikováno v: Journal of ethnopharmacology. 200

Ethnopharmacological relevance The genus Hyptis comprehends almost 400 species widespread in tropical and temperate regions of America. The use of Hyptis spicigera Lam. (Lamiaceae) is reported in traditional medicine due to its gastroprotective, anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb678ff149b444fecc41b12315df113
https://pubmed.ncbi.nlm.nih.gov/28213106

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Antidepressant-like effect of pramipexole in an inflammatory model of depression

Autor: Vicente Lieberknecht, Mauricio P. Cunha, Luiz Felipe de Souza, Alcir Luiz Dafre, Adair R.S. Santos, Rafael C. Dutra, Igor dos Santos Coelho, Ana Lúcia S. Rodrigues, Stella C. Junqueira

Publikováno v: Behavioural brain research. 320

Pramipexole (PPX), a dopamine D2/3 receptor preferring agonist, is currently in use for the treatment of Parkinson's disease symptoms and restless legs syndrome. Recently, anti-inflammatory properties of PPX have been shown in an autoimmune model of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891c8f693febdf962e460a18e4228f49
https://pubmed.ncbi.nlm.nih.gov/27825895

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Physical Exercise Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Peripheral Immune Response and Blood-Brain Barrier Disruption

Autor: Rafael C. Dutra, Priscila S. Souza, Maíra Cola, Rodrigo Marcon, Cláudio T. De Souza, Adair R.S. Santos, Talita Tuon, Giulia S. Pedroso, João B. Calixto, Ricardo A. Pinho, Paulo Cesar Lock Silveira, Hemelin R. Farias, Elaine C. D. Gonçalves, Stella C. Junqueira

Publikováno v: Molecular neurobiology. 54(6)

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) caused by demyelination, immune cell infiltration, and axonal damage. Herein, we sought to investigate the influence of physical exercise on mice experiment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8964c28d42b397d4f5abe473b359d0
https://pubmed.ncbi.nlm.nih.gov/27447807

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