Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Stella Finkelstein"'
Autor:
Yixiao Wang, Silke Becker, Stella Finkelstein, Frank M. Dyka, Haitao Liu, Mark Eminhizer, Ying Hao, Richard S. Brush, William J. Spencer, Vadim Y. Arshavsky, John D. Ash, Jianhai Du, Martin-Paul Agbaga, Frans Vinberg, Jessica M. Ellis, Ekaterina S. Lobanova
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The retina is light-sensitive neuronal tissue in the back of the eye. The phospholipid composition of the retina is unique and highly enriched in polyunsaturated fatty acids, including docosahexaenoic fatty acid (DHA). While it is generally
Externí odkaz:
https://doaj.org/article/ad85367e74fe4ef684827fbc22b57206
Autor:
Ekaterina S. Lobanova, Stella Finkelstein, Jing Li, Amanda M. Travis, Ying Hao, Mikael Klingeborn, Nikolai P. Skiba, Raymond J. Deshaies, Vadim Y. Arshavsky
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Proteasomal overload can be found in a broad spectrum of mouse models of retinal degeneration. Here the authors find that overexpressing the PA28α subunit of the 11S proteasome cap increased the number of surviving functional photoreceptor cells in
Externí odkaz:
https://doaj.org/article/f205dd40283c431b8415d04bab375e77
Autor:
Stella Finkelstein, Sidney M. Gospe, Kai Schuhmann, Andrej Shevchenko, Vadim Y. Arshavsky, Ekaterina S. Lobanova
Publikováno v:
Cells, Vol 9, Iss 6, p 1417 (2020)
Phosphoinositides are known to play multiple roles in eukaryotic cells. Although dysregulation of phosphoinositide metabolism in the retina has been reported to cause visual dysfunction in animal models and human patients, our understanding of the ph
Externí odkaz:
https://doaj.org/article/6f12454b7f954de0afa35d9f48757ee3
Autor:
Zachary A. Steelman, L. Martin, Adam Wax, Ziyun Yang, Vadim Y. Arshavsky, Kengyeh K. Chu, Ge Song, Stella Finkelstein, Sina Farsiu
Publikováno v:
Biomedical Applications of Light Scattering XI.
We present results from depth-resolved light scattering measurements of triple transgenic mouse retinas for Alzheimer’s Disease (AD) using a multimodal coherent imaging system. Use of a co-registered angle-resolved low-coherence interferometry (a/L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1e7dd7198103f0c3ab73ff4b2cba266
https://doi.org/10.1117/12.2576911
https://doi.org/10.1117/12.2576911
Autor:
Vadim Y. Arshavsky, Zachary A. Steelman, Adam Wax, Ge Song, Stella Finkelstein, L. Martin, Sina Farsiu, Ziyun Yang, Kengyeh K. Chu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
We acquired depth-resolved light scattering measurements from the retinas of triple transgenic Alzheimer’s Disease (3xTg-AD) mice and wild type (WT) age-matched controls using co-registered angle-resolved low-coherence interferometry (a/LCI) and op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b19958fcbfd6e915916c804cd3dea0c
http://europepmc.org/articles/PMC7220911
http://europepmc.org/articles/PMC7220911
Publikováno v:
eNeuro
Inherited retinal degenerations originate from mutations in >300 genes, many of which cause the production of misfolded mutant photoreceptor proteins that are ultimately degraded by the ubiquitin-proteasome system (UPS). It was previously shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabd0ed2fd8615e728acd426838124a0
http://europepmc.org/articles/PMC6948925
http://europepmc.org/articles/PMC6948925
Autor:
Martha A. Cady, Kai Schuhmann, Tylor R. Lewis, John D. Ash, Ying Hao, Vadim Y. Arshavsky, Andrej Shevchenko, Stella Finkelstein, Casey Keuthan, Ekaterina S. Lobanova, Marie E. Burns
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 39, iss 49
J Neurosci
J Neurosci
Retinal photoreceptor cells contain the highest concentration of docosahexaenoic acid (DHA) in our bodies, and it has been long assumed that this is critical for supporting normal vision. Indeed, early studies using DHA dietary restriction documented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3121dcb635f04238a9b592f1ab6a39
https://escholarship.org/uc/item/3ph1g392
https://escholarship.org/uc/item/3ph1g392
Autor:
Ying Hao, Stella Finkelstein, Ekaterina S. Lobanova, Nikolai P. Skiba, Mikael Klingeborn, Amanda M. Travis, Jing Li, Raymond J. Deshaies, Vadim Y. Arshavsky
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Inherited retinal degenerations, affecting more than 2 million people worldwide, are caused by mutations in over 200 genes. This suggests that the most efficient therapeutic strategies would be mutation independent, i.e., targeting common pathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e696193168c35362191efb4c72740c3
https://doi.org/10.1038/s41467-018-04117-8
https://doi.org/10.1038/s41467-018-04117-8
Autor:
Paige M. Dexter, William J. Spencer, Stella Finkelstein, Vadim Y. Arshavsky, Nikolai P. Skiba, Ekaterina S. Lobanova
Publikováno v:
eNeuro. 5(3)
The heterotrimeric G-protein transducin mediates visual signaling in vertebrate photoreceptor cells. Many aspects of the function of transducin were learned from knock-out mice lacking its individual subunits. Of particular interest is the knockout o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e77f0de8c82d213ea5c039415c152d0
https://pubmed.ncbi.nlm.nih.gov/29911170
https://pubmed.ncbi.nlm.nih.gov/29911170
Autor:
Vadim Y. Arshavsky, Rolf Herrmann, Wen-Tao Deng, Nikolai P. Skiba, Ellen R. Weiss, Boris Reidel, William W. Hauswirth, Stella Finkelstein, Rebecca Jo, Ekaterina S. Lobanova
Publikováno v:
The Journal of Neuroscience. 30:6815-6824
The remarkable ability of our vision to function under ever-changing conditions of ambient illumination is mediated by multiple molecular mechanisms regulating the light sensitivity of rods and cones. One such mechanism involves massive translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c0919cfced3e6937c9a6df35a6bca8
https://doi.org/10.1523/jneurosci.0613-10.2010
https://doi.org/10.1523/jneurosci.0613-10.2010