Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Stelios T Andreadis"'
Autor:
Pihu Mehrotra, James Jablonski, John Toftegaard, Yali Zhang, Shahryar Shahini, Jianmin Wang, Carey W. Hung, Reilly Ellis, Gabriella Kayal, Nika Rajabian, Song Liu, Kelly C. S. Roballo, Susan B. Udin, Stelios T. Andreadis, Kirkwood E. Personius
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Peripheral Nerve Injuries (PNI) affect more than 20 million Americans and severely impact quality of life by causing long-term disability. PNI is characterized by nerve degeneration distal to the site of nerve injury resulting in long period
Externí odkaz:
https://doaj.org/article/b6d34f0cfb5e4f448addffc2432a0236
Autor:
Georgios Tseropoulos, Pihu Mehrotra, Ashis Kumer Podder, Emma Wilson, Yali Zhang, Jianmin Wang, Alison Koontz, Nan Papili Gao, Rudiyanto Gunawan, Song Liu, Laura M. Feltri, Marianne E. Bronner, Stelios T. Andreadis
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Neural Crest cells (NC) are a multipotent cell population that give rise to a multitude of cell types including Schwann cells (SC) in the peripheral nervous system (PNS). Immature SC interact with neuronal axons via the neuregulin 1 (NRG1) l
Externí odkaz:
https://doaj.org/article/42ef817889b942149013f1f69c71619c
Autor:
Samantha E. Cassel, Breanna M. Huntington, Wilfred Chen, Pedro Lei, Stelios T. Andreadis, April M. Kloxin
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026127-026127-17 (2024)
Activation of fibroblasts is pivotal for wound healing; however, persistent activation leads to maladaptive processes and is a hallmark of fibrosis, where disease mechanisms are only partially understood. Human in vitro model systems complement in vi
Externí odkaz:
https://doaj.org/article/cb5866edd5e14cf7bca82c5be176521e
Autor:
Yayu Liu, Pedro Lei, Ronel Z. Samuel, Anagha M. Kashyap, Theodore Groth, Wiam Bshara, Sriram Neelamegham, Stelios T. Andreadis
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2056-2073 (2023)
During epithelial–mesenchymal transition (EMT) in cancer progression, tumor cells switch cadherin profile from E‐cadherin to cadherin‐11 (CDH11), which is accompanied by increased invasiveness and metastatic activity. However, the mechanism thr
Externí odkaz:
https://doaj.org/article/61a8c0a37da6437793ec0e2602e16bc1
Autor:
Debanik Choudhury, Na Rong, Hamsa Vardini Senthil Kumar, Sydney Swedick, Ronel Z. Samuel, Pihu Mehrotra, John Toftegaard, Nika Rajabian, Ramkumar Thiyagarajan, Ashis K. Podder, Yulun Wu, Shahryar Shahini, Kenneth L. Seldeen, Bruce Troen, Pedro Lei, Stelios T. Andreadis
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113738- (2024)
Summary: Mitochondrial dysfunction is a hallmark of cellular senescence, with the loss of mitochondrial function identified as a potential causal factor contributing to senescence-associated decline in cellular functions. Our recent findings revealed
Externí odkaz:
https://doaj.org/article/7e0989fdc4cd4210b9b77af2703db105
Autor:
Nika Rajabian, Izuagie Ikhapoh, Shahryar Shahini, Debanik Choudhury, Ramkumar Thiyagarajan, Aref Shahini, Joseph Kulczyk, Kendall Breed, Shilpashree Saha, Mohamed Alaa Mohamed, Susan B. Udin, Aimee Stablewski, Kenneth Seldeen, Bruce R. Troen, Kirkwood Personius, Stelios T. Andreadis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Aged myoblasts suffer from impaired glycolysis and insulin resistance, but increase methionine catabolism, possibly to meet energetic demands. Here, authors show that inhibiting methionine metabolism via NANOG reprogramming or MAT2A inhibition restor
Externí odkaz:
https://doaj.org/article/20d14dcf72624910a7c1176a420cedc0
Downregulation of YAP Activity Restricts P53 Hyperactivation to Promote Cell Survival in Confinement
Autor:
Farnaz Hemmati, Ayuba Akinpelu, Jiyeon Song, Farshad Amiri, Anya McDaniel, Collins McMurray, Alexandros Afthinos, Stelios T. Andreadis, Andrew V. Aitken, Vinicia C. Biancardi, Sharon Gerecht, Panagiotis Mistriotis
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract Cell migration through confining three dimensional (3D) topographies can lead to loss of nuclear envelope integrity, DNA damage, and genomic instability. Despite these detrimental phenomena, cells transiently exposed to confinement do not us
Externí odkaz:
https://doaj.org/article/0ffb15d0004f4eed9ae794c90274936d
Autor:
Mohamed Alaa Mohamed, Aref Shahini, Nika Rajabian, Julia Caserto, Ahmed M.A. El-Sokkary, Magda A. Akl, Stelios T. Andreadis, Chong Cheng
Publikováno v:
Bioactive Materials, Vol 6, Iss 7, Pp 2120-2133 (2021)
Biodegradable elastomers are important emerging biomaterials for biomedical applications, particularly in the area of soft-tissue engineering in which scaffolds need to match the physicochemical properties of native tissues. Here, we report novel fas
Externí odkaz:
https://doaj.org/article/d52b7429bb4343ee912e28d8ef2fc017
Autor:
Randall J. Smith, Bita Nasiri, Julien Kann, Donald Yergeau, Jonathan E. Bard, Daniel D. Swartz, Stelios T. Andreadis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Acellular tissue engineered vessels functionalised with VEGF are coated with a layer of endothelial cells after in vivo implantation, but the source of the cells are unknown. Here the authors provide evidence that monocytes expressing VEGF receptors
Externí odkaz:
https://doaj.org/article/87d73685b94348bba1f801f3cacbabba
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 3, Pp 328-341 (2020)
Abstract Neural crest (NC) cells are a multipotent stem cell population that give rise to a diverse array of cell types in the body, including peripheral neurons, Schwann cells (SC), craniofacial cartilage and bone, smooth muscle cells, and melanocyt
Externí odkaz:
https://doaj.org/article/debae27fc1ae4ca49c38909059ad3bcc