Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stelios Florinas"'
Autor:
Shaoyi Chen, Stelios Florinas, Abigail Teitgen, Ze-Qi Xu, Changshou Gao, Herren Wu, Kazunori Kataoka, Horacio Cabral, R. James Christie
Publikováno v:
Science and Technology of Advanced Materials, Vol 18, Iss 1, Pp 666-680 (2017)
Antibodies and antigen-binding fragments (Fabs) can be used to modify the surface of nanoparticles for enhanced target binding. In our previous work, site-specific conjugation of Fabs to polymeric micelles using conventional methods was limited to ap
Externí odkaz:
https://doaj.org/article/b423f9a767e449a38ca1171b022ccd48
Autor:
Takuya Miyazaki, Shaoyi Chen, Stelios Florinas, Kazunori Igarashi, Yu Matsumoto, Tatsuya Yamasoba, Ze-Qi Xu, Herren Wu, Changshou Gao, Kazunori Kataoka, R. James Christie, Horacio Cabral
Publikováno v:
ACS Nano. 16:12290-12304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f79f12a3d50d66769151c02f0cb8ae6b
https://doi.org/10.1021/acsnano.2c03170
https://doi.org/10.1021/acsnano.2c03170
Autor:
Charles J. Bieberich, Ronghui Ma, Ronald James Christie, Stelios Florinas, Marie-Christine Daniel, Qimei Gu, Arunendra Saha Ray, Shuaishuai Liu, Liang Zhu
Publikováno v:
Journal of Thermal Science and Engineering Applications. 12
In this study, we performed in vivo experiments on mice to evaluate whether whole-body hyperthermia enhances nanoparticle delivery to PC3 (prostatic cancer) tumors. PC3 xenograft tumors in immunodeficient mice were used in this study. The mice in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acbe1d87e04cb1869660a68420424220
https://doi.org/10.1115/1.4046520
https://doi.org/10.1115/1.4046520
Autor:
Haihong Zhong, Stelios Florinas, André H. St. Amant, Herren Wu, Javier Read de Alaniz, Daniel Lemen, Christine Fazenbaker, R. James Christie, Shenlan Mao, Changshou Gao
Publikováno v:
Bioconjugate chemistry. 29(7)
The thiol-maleimide linkage is widely used for antibody-drug conjugate (ADC) production; however, conjugation of maleimide-drugs could be improved by simplified procedures and reliable conjugate stability. Here, we report the evaluation of electron-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1e8c7fc091beea50d2bcc596444c14
https://pubmed.ncbi.nlm.nih.gov/29932647
https://pubmed.ncbi.nlm.nih.gov/29932647
Autor:
R. James Christie, Ze Qi Xu, Abigail Teitgen, Changshou Gao, Shaoyi Chen, Herren Wu, Kazunori Kataoka, Horacio Cabral, Stelios Florinas
Publikováno v:
Science and Technology of Advanced Materials, Vol 18, Iss 1, Pp 666-680 (2017)
Antibodies and antigen-binding fragments (Fabs) can be used to modify the surface of nanoparticles for enhanced target binding. In our previous work, site-specific conjugation of Fabs to polymeric micelles using conventional methods was limited to ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0737d2382cb3ca4d47e27c8ef2bb9fa3
Autor:
Kazunori Kataoka, Leslie Wetzel, Stelios Florinas, Ronald James Christie, Jonathan Rios-Doria, Shabazz Novarra, Manuel Baca, Ryan N. Gilbreth, Horacio Cabral
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 234
Receptor clustering is important for signaling among the therapeutically relevant TNFR superfamily of receptors. In nature, this clustering is driven by trimeric ligands often presented in large numbers as cell surface proteins. Molecules capable of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da69377479b4d81b1de7f91f1e4a32d7
https://pubmed.ncbi.nlm.nih.gov/27212104
https://pubmed.ncbi.nlm.nih.gov/27212104
Autor:
Joanne Ayriss, Anjaneyulu Dirisala, Shaoyi Chen, Stelios Florinas, Ryan Fleming, Ze Qi Xu, Herren Wu, Nazzareno Dimasi, Kazunori Kataoka, Changshou Gao, Ryan N. Gilbreth, Horacio Cabral, Marc Liu, R. James Christie, Lilian van Vlerken-Ysla
Publikováno v:
Biomacromolecules. 17(5)
Targeted nanomedicines are a promising technology for treatment of disease; however, preparation and characterization of well-defined protein-nanoparticle systems remain challenging. Here, we describe a platform technology to prepare antibody binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e3a83d3815ad44676975ab2387e996
https://pubmed.ncbi.nlm.nih.gov/27007881
https://pubmed.ncbi.nlm.nih.gov/27007881
The major drawback hampering siRNA therapies from being more widely accepted in clinical practice is its insufficient accumulation at the target site mainly due to poor cellular uptake and rapid degradation in serum. Therefore, we designed a novel po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea345499f54b9b3ce27b847b6db5ba0
https://europepmc.org/articles/PMC4025968/
https://europepmc.org/articles/PMC4025968/
RNAi-based gene therapy for cancer treatment has not shown significant clinical impact due to poor siRNA delivery to the target site. Here, we design a non-viral siRNA gene carrier using a combination of an arginine-grafted bioreducible polymer (ABP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b841c30d4b9309f2a6ebbedac46ff02
https://europepmc.org/articles/PMC3646922/
https://europepmc.org/articles/PMC3646922/