Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Stelios Eleftheratos"'
Publikováno v:
Journal of chemical theory and computation. 9(2)
Aminoadamantane derivatives, such as amantadine and rimantadine, have been reported to block the M2 membrane protein of influenza A virus (A/M2TM), but their use has been discontinued due to reported resistance in humans. Understanding the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef108d439e5a878f6e00b1e6a9d85b99
https://pubmed.ncbi.nlm.nih.gov/26588768
https://pubmed.ncbi.nlm.nih.gov/26588768
Autor:
Alan J. Hay, Gabriella Maria Pia Ortore, Adriano Martinelli, Antonios Kolocouris, Stephen R. Martin, Philip Spearpoint, Stelios Eleftheratos
Interaction of aminoadamantanes with the influenza A virus M2 proton channel was analyzed by docking simulations of a series of synthetic aminoadamantane derivatives, of differing binding affinity, into the crystal structure of the transmembrane (M2T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e2e2ef5a44b3bb43513952722edea7
http://hdl.handle.net/11568/143381
http://hdl.handle.net/11568/143381
