Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Stelios, Kakolyris"'
Autor:
Vassilis Georgoulias, M. Agelidou, Ioannis Boukovinas, Nikolaos Androulakis, A. Agelidou, Charalambos Christophyllakis, Stelios Giassas, X. Tsiafaki, Vassilis Chandrinos, Athanasios G. Pallis, Georgia Pavlakou, Aris Polyzos, Nikolaos Kentepozidis, Lambros Lamvakas, Stelios Kakolyris, Sophia Agelaki
Publikováno v:
Journal of Thoracic Oncology. 3:505-510
IntroductionThirty to 40% of patients with non-small cell lung cancer (NSCLC) are older than 70 years and rarely are enrolled in clinical trials. Moreover, in clinical practice, >75% of patients older than 65 years with metastatic NSCLC never receive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0020327429199ead8bc7fe0dd9cad875
https://doi.org/10.1097/jto.0b013e31816b4b32
https://doi.org/10.1097/jto.0b013e31816b4b32
Autor:
Nikol Spathari, Anastasios J. Karayiannakis, Anastasia Micheli, Ekaterini Chatzaki, Stelios Kakolyris, Loukas Kaklamanis, Miltiades Trichas, Vasilis Georgoulias, K. Amarantidis
Publikováno v:
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 15:445-451
Angiogenesis is essential for tumor growth and metastasis. It is controlled by multiple factors, one of the most important being vascular endothelial growth factor (VEGF). VEGF and p53 expression were evaluated in 16 hyperplastic polyps, 35 solitary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b845f57b311fc9d3e95f21cd24ce6c1
https://doi.org/10.3727/096504005776568282
https://doi.org/10.3727/096504005776568282
Autor:
Michael I. Koukourakis, Alexandra Giatromanolaki, Stelios Kakolyris, Efthimios Sivridis, Dimitris Mavroudis, M. Perraki, Vassilis Georgoulias, Chrysa Mavroudi, Charalambos Kouroussis
Publikováno v:
International Journal of Cancer. 108:620-627
The assessment of tumor molecular features in combination with the detection of occult malignant cells may provide important clinical information, beyond the standard staging of breast cancer. Using a nested RT-PCR technique, we assessed prospectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88bf5e686a4c6bd6297c65a642a1cbf
https://doi.org/10.1002/ijc.11593
https://doi.org/10.1002/ijc.11593
Autor:
Vassilis Georgoulias, G. Retalis, Stelios Kakolyris, Efthimios Sivridis, Michael I. Koukourakis, Chryssi Frangiadaki, Alexandra Giatromanolaki, Charalambos Kouroussis
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 52:144-155
Although the role of radiotherapy (RT) after mastectomy in reducing the local relapse rate is well established, its impact on overall survival is strongly questioned. Up to 70% of patients will not benefit from additional RT, and a "wait and see" pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8afda0930fce9620d1b16084c2100b8
https://doi.org/10.1016/s0360-3016(01)01759-x
https://doi.org/10.1016/s0360-3016(01)01759-x
Autor:
John Souglakos, Vassilis Georgoulias, Alexios Matikas, Stelios Kakolyris, Aris Polyzos, Lambros Vamvakas, Dora Hatzidaki, Ioannis Boukovinas, Athanasios Karampeazis, Charalampos Christophylakis
Publikováno v:
BMC Cancer
Background Colorectal cancer (CRC) is a disease of the elderly. However, geriatric patients are often excluded from clinical trials. The combination of capecitabine, oxaliplatin and bevacizumab (XELOX/BEV) has not been assessed in an elderly populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1ffe601959d075040d489f3c653d0c
https://doi.org/10.1186/1471-2407-14-277
https://doi.org/10.1186/1471-2407-14-277
Autor:
Sophia Agelaki, John Souglakos, N. Vardakis, Ch. Kouroussis, Lambros Vamvakas, Kostas Kalbakis, V. Georgoulias, Stelios Kakolyris
Publikováno v:
Lung Cancer. 34:71-76
Irinotecan (CPT-11) and cisplatin (P) are both active agents against non-small cell lung cancer (NSCLC), and their combination has shown in vitro an additive or synergistic effect. We conducted a phase II study to determine the toxicity and efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded54c20837d3dddcd95e091f2ee13df
https://doi.org/10.1016/s0169-5002(01)00384-1
https://doi.org/10.1016/s0169-5002(01)00384-1
Autor:
M Christodoulakis, D. Mavroudis, Stelios Kakolyris, Konstantinos Kalbakis, Lambros Vamvakas, John Souglakos, Kostas Stylianou, Ch. Kouroussis, Sophia Agelaki, V. Georgoulias
Publikováno v:
British Journal of Cancer
The purpose of this study was to evaluate the activity and tolerance of high-dose leucovorin (LV) and infusional 5-fluorouracil (5-FU) in combination with conventional doses of cyclophosphamide (CPM) as salvage chemotherapy in patients with metastati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca18bda02704c8e4a209f5dee32fb9d5
https://doi.org/10.1054/bjoc.2001.2001
https://doi.org/10.1054/bjoc.2001.2001
Autor:
Stelios Kakolyris, Marian Taylor, Stephen B. Fox, Jan Grøndahl-Hansen, Adrian L. Harris, Kevin C. Gatter
Publikováno v:
The Journal of Pathology. 195:236-243
The generation of urokinase plasminogen activator (uPA) by tumours is an important pathway for neoplastic cell invasion and metastasis. Indeed in several tumour types, elevated levels of uPA, its receptor (uPAR) or its inhibitor plasminogen activator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e0c40077e58dff34c10d4e5b1472eb
https://doi.org/10.1002/path.931
https://doi.org/10.1002/path.931
Autor:
John Souglakos, D. Mavroudis, N. Vardakis, Charalambos Kouroussis, Nikos Androulakis, J. Romanos, Athanasios Kotsakis, Michael I. Koukourakis, Kostas Kalbakis, Stelios Kakolyris, V. Georgoulias
Publikováno v:
Oncology. 60:207-213
Objective: Irinotecan (CPT-11) has shown considerable activity in colorectal cancer, and its combination with 5-fluorouracil (5-FU) represents an attractive approach. A phase I study was conducted to determine the maximum tolerated dose (MTD) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4504b36a6f4f4da406b07d46f78e079c
https://doi.org/10.1159/000055320
https://doi.org/10.1159/000055320
Autor:
Adrian L. Harris, Stelios Kakolyris, Trevor J. Powles, Sue Ashley, Andreas Makris, Mitch Dowsett
Publikováno v:
Cancer. 85:1996-2000
Background The intensity of angiogenesis, as measured by microvessel density, is a strong independent predictor of survival in breast carcinoma patients. The impact of chemotherapy and/or endocrine therapy on this process is unknown. Methods Histolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed5c18e7bf6fc28452d0d3d9c962115
https://doi.org/10.1002/(sici)1097-0142(19990501)85:9%3c1996::aid-cncr17%3e3.0.co
https://doi.org/10.1002/(sici)1097-0142(19990501)85:9%3c1996::aid-cncr17%3e3.0.co