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The aptamer BC 007 completely neutralizes agonistic autoantibodies directed against β1-adrenoceptors
Autor:
Becker, Niels-Peter, Mueller, Johannes, Haberland, Annekathrin, Wenzel, Katrin, Wallukat, Gerd, Goettel, Peter, Schulze- Rothe, Sarah, Schimke, Ingolf, Golor, Georg, Grossmann, Matthias, Sinn, Angela, Steiper, Martina, Yilmaz, Tuba, Wallukat, Anne, Davideit, Hanna, Becker, Susanne
Background: 80 percent of patients with non-ischemic heart failure (HF) and reduced ejection fraction have autoantibodies against β1- adrenoceptors (β1-AAB), which cause and/or sustain HF. The removal of β1-AAB by immunoadsorption (IA) leads to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5643637a2ccd9e4ac4e1720f4cc72cd
Autor:
Mueller, Johannes, Haberland, Annekathrin, Becker, Niels-Peter, Wenzel, Katrin, Wallukat, Gerd, Goettel, Peter, Schulze-Rothe, Sarah, Schimke, Ingolf, Golor, Georg, Grossmann, Matthias, Sinn, Angela, Steiper, Martina, Yilmaz, Tuba, Wallukat, Anne, Davideit, Hanna
Publikováno v:
In Journal of the American College of Cardiology 10-12 March 2018 71(11) Supplement:A645-A645