Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Steinunn, Snorradottir"'
Autor:
Jona Saemundsdottir, Arnaldur Gylfason, Hreinn Stefansson, Steinunn Snorradottir, Gudmar Thorleifsson, Brynjar O. Jensson, Sverrir T. Sverrisson, Gisli Masson, Brynjar Sigurdsson, Olafur Th Magnusson, Agnar Helgason, Unnur Styrkarsdottir, Olafur A. Stefansson, Sigurjon A. Gudjonsson, Hannes Hauswedell, Pall I. Olason, Margret Asgeirsdottir, Páll Melsted, Droplaug N Magnusdottir, Marteinn T. Hardarson, Asmundur Oddsson, Gisli H. Halldorsson, Kristjan Norland, Hannes P. Eggertsson, Thorunn Rafnar, Kari Stefansson, Hilma Holm, Unnur Thorsteinsdottir, Emilia Sobech, Doruk Beyter, Ogmundur Eiriksson, Kristjan H. S. Moore, Brynja D. Sigurpalsdottir, Gunnar Th. Sigurdsson, Ingileif Jonsdottir, Guillaume Holley, Snaedis Kristmundsdottir, Kari Kristinsson, Bjarni V. Halldorsson, Gunnar K. Pálsson, Magnus O. Ulfarsson, Frosti Jonsson, Daniel F. Gudbjartsson, Vinicius Tragante, Patrick Sulem, Florian Zink, Gardar Sveinbjornsson, Hakon Jonsson
We describe the analysis of whole genome sequences (WGS) of 150,119 individuals from the UK biobank (UKB). This constitutes a set of high quality variants, including 585,040,410 SNPs, representing 7.0% of all possible human SNPs, and 58,707,036 indel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ec97dcc172cfe882dfcfb8c2d1ae42a
https://doi.org/10.1101/2021.11.16.468246
https://doi.org/10.1101/2021.11.16.468246
Autor:
Bjarni V, Halldorsson, Hannes P, Eggertsson, Kristjan H S, Moore, Hannes, Hauswedell, Ogmundur, Eiriksson, Magnus O, Ulfarsson, Gunnar, Palsson, Marteinn T, Hardarson, Asmundur, Oddsson, Brynjar O, Jensson, Snaedis, Kristmundsdottir, Brynja D, Sigurpalsdottir, Olafur A, Stefansson, Doruk, Beyter, Guillaume, Holley, Vinicius, Tragante, Arnaldur, Gylfason, Pall I, Olason, Florian, Zink, Margret, Asgeirsdottir, Sverrir T, Sverrisson, Brynjar, Sigurdsson, Sigurjon A, Gudjonsson, Gunnar T, Sigurdsson, Gisli H, Halldorsson, Gardar, Sveinbjornsson, Kristjan, Norland, Unnur, Styrkarsdottir, Droplaug N, Magnusdottir, Steinunn, Snorradottir, Kari, Kristinsson, Emilia, Sobech, Helgi, Jonsson, Arni J, Geirsson, Isleifur, Olafsson, Palmi, Jonsson, Ole Birger, Pedersen, Christian, Erikstrup, Søren, Brunak, Sisse Rye, Ostrowski, Gudmar, Thorleifsson, Frosti, Jonsson, Pall, Melsted, Ingileif, Jonsdottir, Thorunn, Rafnar, Hilma, Holm, Hreinn, Stefansson, Jona, Saemundsdottir, Daniel F, Gudbjartsson, Olafur T, Magnusson, Gisli, Masson, Unnur, Thorsteinsdottir, Agnar, Helgason, Hakon, Jonsson, Patrick, Sulem, Thomas, Werge
Publikováno v:
Nature. 607(7920)
Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic diversity depends on a comprehensive and reliable characterization of both sequences and phenotypic variation. Over the past decade, insights into this relatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fc382f82eda30e2487a10b47c2249b6
https://pubmed.ncbi.nlm.nih.gov/35859178
https://pubmed.ncbi.nlm.nih.gov/35859178
Autor:
Ingrid Kockum, Valdis B. Guðmundsdóttir, Marcela Sandoval-Velasco, Agnar Helgason, Steinunn Kristjánsdóttir, Elisabet Linda Thordardottir, Kari Stefansson, Lilja Árnadóttir, Anuradha Jagadeesan, Margrét Einarsdóttir, M. Thomas P. Gilbert, Ólafur Þ. Magnússon, Tomas Olsson, Droplaug N Magnusdottir, Ellen Gunnarsdóttir, Eivind Hovig, Joe W. Walser, Hakon Jonsson, S. Sunna Ebenesersdóttir, Kristjan H. S. Moore, Lars Alfredsson, Shyam Gopalakrishnan, Gianpiero L. Cavalleri, Pål Møller, Steinunn Snorradottir, Edmund Gilbert, Ásgeir Sigurðsson, Thomas Hansen, Carles Lalueza-Fox, Thomas Werge
Publikováno v:
Science
Founder effects in modern populations The genomes of ancient humans can reveal patterns of early human migration (see the Perspective by Achilli et al. ). Iceland has a genetically distinct population, despite relatively recent settlement (∼1100 ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe31640af893b0d1ae47b4fbb766961
http://hdl.handle.net/11250/2592828
http://hdl.handle.net/11250/2592828
Autor:
Andrea Flex, Jeffrey R. Gulcher, Einar M. Valdimarsson, David A. Collier, Svati H. Shah, Harland Austin, Annette F. Baas, Hreinn Stefansson, Kristinn P. Magnusson, Viola Vaccarino, Bengt Lindblad, Gudmundur Thorgeirsson, Gregory T. Jones, Roberto Pola, Janet T. Powell, Gabriel J.E. Rinkel, Jan D. Blankensteijn, Shantel Weinsheimer, Gerard Tromp, Juha Hernesniemi, Helena Kuivaniemi, Thorbjorg Jonsdottir, Konstantinos Kostulas, Natzi Sakalihasan, Arshed A. Quyyumi, Dana Magnusdottir, Hulda B Magnadottir, Cisca Wijmenga, Knut Borch-Johnsen, Daniel J. Rader, Torben Jørgensen, Robert E. Ferrell, Steinunn Snorradottir, Guy M. Lenk, Valgerdur Steinthorsdottir, Torben Hansen, Raymond Limet, Diederick E. Grobbee, Solveig Gretarsdottir, Sigurlaug Sveinbjörnsdóttir, Oluf Pedersen, Anna Helgadottir, Allan I. Levey, Ebba Palsdottir, Augustine Kong, Juha Jääskeläinen, Jan Hillert, Stefan E Matthiasson, Gunnar Sigurdsson, Rafn Benediktsson, Joep A.W. Teijink, G. Bragi Walters, Eric L.G. Verhoeven, Gudmar Thorleifsson, Andre M. van Rij, Gudmundur H. Gudmundsson, Ynte M. Ruigrok, Karl Andersen, Anders Gottsäter, Gitte Andersen, Christopher B. Granger, Antti Ronkainen, Yoshiki Kyo, Mika Niemelä, Kari Stefansson, Andrei Manolescu, Unnur Thorsteinsdottir, Muredach P. Reilly
Publikováno v:
Nature Genetics, 40(2), 217-224. Nature Publishing Group
Nature Genetics, 40, 217-24
Nature Genetics, 40, 2, pp. 217-24
Nature Genetics, 40, 217-24
Nature Genetics, 40, 2, pp. 217-24
Contains fulltext : 70663.pdf (Publisher’s version ) (Closed access) Recently, two common sequence variants on 9p21, tagged by rs10757278-G and rs10811661-T, were reported to be associated with coronary artery disease (CAD) and type 2 diabetes (T2D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774714d380f6a63be5d5525bba38f18b
https://doi.org/10.1038/ng.72
https://doi.org/10.1038/ng.72
Autor:
Valur Emilsson, Shyamali Ghosh, Yuanxiu Chen, Unnur Styrkarsdottir, Ayo Doumatey, Mark E. Gurney, Juliana C.N. Chan, Kerrie Lashley, Adebowale Adeyemo, Augustine Kong, Kari Stefansson, Inga Reynisdottir, Gunnar Sigurdsson, Marten H. Hofker, Jeffrey R. Gulcher, Oluf Pedersen, Cisca Wijmenga, Hjordis Bjarnason, Wing-Yee So, Torben Hansen, Daniel J. Rader, Thorbjorg Jonsdottir, Knut Borch-Johnsen, Valgerdur Steinthorsdottir, Claus Christiansen, Guanjie Chen, Charles N. Rotimi, Gudmar Thorleifsson, Rafn Benediktsson, Torben Jørgensen, Robert L. Wilensky, Vilmundur Gudnason, Hanxia Huang, Unnur Thorsteinsdottir, Muredach P. Reilly, Adam Baker, Yu Z. Bagger, Gitte Andersen, Steinunn Snorradottir, Jana V. van Vliet-Ostaptchouk, G. Bragi Walters, Ronald Ching-Wa Ma, Jie Zhou, Maggie C.Y. Ng, Solveig Gretarsdottir
Publikováno v:
Nature Genetics, 39(6), 770-775. Nature Publishing Group
We conducted a genome-wide association study for type 2 diabetes (T2D) in Icelandic cases and controls, and we found that a previously described variant in the transcription factor 7-like 2 gene (TCF7L2) gene conferred the most significant risk. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7f08f970e64f0526760d315bec751e
https://doi.org/10.1038/ng2043
https://doi.org/10.1038/ng2043
Autor:
Sigrún Siguróaróóttir, Ásdís Baldursdóttir, Jeffrey R. Gulcher, Ragnheióur I. Bjarnaóóttir, Reynir Tómas Geirsson, Birgir Palsson, Birkir Thor Bragason, Thorlakur Jonsson, Augustine Kong, Reynir Arngrímsson, Dan L. Nicolae, A. M. A. Lachmeijer, Kari Stefansson, Anna S. Einarsdóttir, Michael L. Frigge, Steinunn Snorradottir, Hreinn Stefansson
Publikováno v:
Human Molecular Genetics. 8:1799-1805
Pre-eclampsia is a common and serious disease and a major cause of maternal and infant mortality. Antenatal care systems world-wide screen for signs of the disease such as hypertension and proteinuria. Unlike most other human disorders it impacts two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9b3c3c9610406ef996a5a2a7fb8c3c
https://doi.org/10.1093/hmg/8.9.1799
https://doi.org/10.1093/hmg/8.9.1799
Autor:
Tuan V. Nguyen, Daniel F. Gudbjartsson, Claus Christiansen, Jona Saemundsdottir, Solveig Gretarsdottir, Thorbjorg Jonsdottir, Jeffrey R. Gulcher, John A. Eisman, Gunnar Sigurdsson, Steinunn Snorradottir, Kari Stefansson, G. Bragi Walters, Unnur Thorsteinsdottir, Unnur Styrkarsdottir, Thorvaldur Ingvarsson, Augustine Kong, Peter Alexandersen, Bjarni V. Halldorsson
Publikováno v:
Nature Genetics. 41:15-17
In an extended genome-wide association study of bone mineral density among 6,865 Icelanders and a follow-up in 8,510 subjects of European descent, we identified four new genome-wide significant loci. These are near the SOST gene at 17q21, the MARK3 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317030f42d1b3dbcea61123053c59f9f
https://doi.org/10.1038/ng.284
https://doi.org/10.1038/ng.284
Autor:
Dorine W. Swinkels, Christina A. Hulsbergen-van de Kaa, Magali Mouy, Jeffrey R. Gulcher, Rajesh Kumar, Erik B. Cornel, Margret Jakobsdottir, Henk Vergunst, Thorunn Rafnar, Peter Rudnai, Simonetta Guarrera, Kvetoslava Koppova, Baldvin Kristjansson, J. Alfred Witjes, Gudmundur Geirsson, D. Timothy Bishop, Jon Thor Bergthorsson, Sigfus Nikulasson, Daniel F. Gudbjartsson, Stefano Porru, Silvia Polidoro, Gunnar Steineck, Simon N. Stacey, Marcello Campagna, Eliane Kellen, Augustine Kong, Maurice P. Zeegers, Eugene Gurzau, Giuseppe Matullo, Martine Ploeg, Kari T. Kristinsson, Anne E. Kiltie, Sigurjon A. Gudjonsson, Frank Buntinx, Thorgeir E. Thorgeirsson, Julius Gudmundsson, Steinunn Snorradottir, Patrick Sulem, Cecilia Arici, Tony Fletcher, Jose I. Mayordomo, Lambertus A. Kiemeney, Gudmar Thorleifsson, Manuel Sanchez, Vigdis Petursdottir, Kari Stefansson, Margaret A. Knowles, Berta Saez, Frank Geller, Katja K H Aben, Petra J. de Verdier, Klaus Golka, Thorarinn Blondal, Asgeir Sigurdsson, Paolo Vineis, Donatella Placidi, Steinunn Thorlacius, Unnur Thorsteinsdottir, Sita H. Vermeulen, Carlotta Sacerdote, Gabriel Valdivia, Charlotta Ryk, Annika Lindblom, Eirikur Jonsson
Publikováno v:
Nature Genetics, 40, 1307-12
Nature Genetics, 40, 11, pp. 1307-12
Nature Genetics, 40(11), 1307-12. Nature Publishing Group
Nature Genetics, 40, 11, pp. 1307-12
Nature Genetics, 40(11), 1307-12. Nature Publishing Group
Contains fulltext : 71044.pdf (Publisher’s version ) (Closed access) We conducted a genome-wide SNP association study on 1,803 urinary bladder cancer (UBC) cases and 34,336 controls from Iceland and The Netherlands and follow up studies in seven ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a616465cc4f80ce9b4bdcaf734cf851
http://hdl.handle.net/11379/29471
http://hdl.handle.net/11379/29471