Quantitative measures of bone shape, cartilage morphometry and joint alignment are associated with disease in an ACLT and MMx rat model of osteoarthritis

Autor: Besler, Bryce A., Schadow, Jemima E., Durongbhan, Pholpat, Steiner, Thomas H., Choo, Ryan J., Zulliger, Martin A., Wilke, Markus, Atal, Kailash, Firminger, Colin, Quintin, Aurelie, Koller, Bruno, Müller, Ralph, Nesic, Dobrila, Stok, Kathryn S.

Publikováno v: In Bone May 2021 146

Three-Dimensional Quantitative Morphometric Analysis (QMA) for In Situ Joint and Tissue Assessment of Osteoarthritis in a Preclinical Rabbit Disease Model

Autor: Stok, Kathryn S, Besler, Bryce A, Steiner, Thomas H, Villarreal Escudero, Ana V, Zulliger, Martin A, Wilke, Markus, Atal, Kailash, Quintin, Aurelie, Koller, Bruno, Müller, Ralph, Nesic, Dobrila

Publikováno v: PLoS ONE, 11 (1)
PLoS ONE, Vol 11, Iss 1, p e0147564 (2016)
Stok, Kathryn S; Besler, Bryce A; Steiner, Thomas H; Villarreal Escudero, Ana V; Zulliger, Martin A; Wilke, Markus; Atal, Kailash; Quintin, Aurelie; Koller, Bruno; Müller, Ralph; Nesic, Dobrila (2016). Three-Dimensional Quantitative Morphometric Analysis (QMA) for In Situ Joint and Tissue Assessment of Osteoarthritis in a Preclinical Rabbit Disease Model. PLoS ONE, 11(1), e0147564. Public Library of Science 10.1371/journal.pone.0147564

This work utilises advances in multi-tissue imaging, and incorporates new metrics which define in situ joint changes and individual tissue changes in osteoarthritis (OA). The aims are to (1) demonstrate a protocol for processing intact animal joints

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a8f794d67b720fd1a915db6c4ae05b

Comprehensive morphological characterisation of arthritis in animal models by micro-CT

Autor: Steiner, Thomas H., Choo, Ryan J., Quintin, A., Villarreal, Ana, Firminger, Colin R., Müller, Ralph, Koller, B., Zulliger, M.A., Nesic, D., Stok, Kathryn S.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c075a74f956b99cccf346029d56650d5

Stochastic amplitude-modulated stretching of Rabbit flexor digitorum profundus tendons reduces stiffness compared to Cyclic Loading but does not affect Tenocyte Metabolism

Autor: Alexander Bürki, Benjamin Gantenbein-Ritter, Stephen J. Ferguson, Thomas H. Steiner

Publikováno v: BMC Musculoskeletal Disorders, Vol 13, Iss 1, p 222 (2012)
Steiner, Thomas H.; Bürki, Alexander; Ferguson, Stephen J.; Gantenbein-Ritter, Benjamin (2012). Stochastic amplitude-modulated stretching of Rabbit flexor digitorum profundus tendons reduces stiffness compared to Cyclic Loading but does not affect Tenocyte Metabolism. BMC musculoskeletal disorders, 13, p. 222. London: BioMed Central 10.1186/1471-2474-13-222
BMC Musculoskeletal Disorders, 13
BMC Musculoskeletal Disorders

Background It has been demonstrated that frequency modulation of loading influences cellular response and metabolism in 3D tissues such as cartilage, bone and intervertebral disc. However, the mechano-sensitivity of cells in linear tissues such as te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccc95474aae5fafb2f788ac75fcd8d8

Yale Textbook of Public Psychiatry

Autor: Dr Selby Jacobs, Dr Jeanne Steiner

Yale Textbook of Public Psychiatry is a comprehensive resource on treatment, rehabilitation, recovery, and public health of persons cared for in organized, publically funded systems of care. Edited and authored by experts in public psychiatry at the