Molecular Dynamics Simulations Elucidate the Molecular Organization of Poly(beta-amino ester) Based Polyplexes for siRNA Delivery.

Autor: Steinegger KM; Department of Pharmacy, Ludwig-Maximilians-University Munich, 81377 Munich, Germany., Allmendinger L; Department of Pharmacy, Ludwig-Maximilians-University Munich, 81377 Munich, Germany., Sturm S; Department of Chemistry, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.; Center for NanoScience (CeNS), Ludwig-Maximilians-University Munich, 80799 Munich, Germany., Sieber-Schäfer F; Department of Pharmacy, Ludwig-Maximilians-University Munich, 81377 Munich, Germany., Kromer APE; Department of Pharmacy, Ludwig-Maximilians-University Munich, 81377 Munich, Germany., Müller-Caspary K; Department of Chemistry, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.; Center for NanoScience (CeNS), Ludwig-Maximilians-University Munich, 80799 Munich, Germany., Winkeljann B; Department of Pharmacy, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.; Center for NanoScience (CeNS), Ludwig-Maximilians-University Munich, 80799 Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Helmholtz Munich, German Center for Lung Research (DZL), 81377 Munich, Germany., Merkel OM; Department of Pharmacy, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.; Center for NanoScience (CeNS), Ludwig-Maximilians-University Munich, 80799 Munich, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Helmholtz Munich, German Center for Lung Research (DZL), 81377 Munich, Germany.

Publikováno v: Nano letters [Nano Lett] 2024 Dec 11; Vol. 24 (49), pp. 15683-15692. Date of Electronic Publication: 2024 Nov 26.