A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents.

Autor: He S; Department of Anesthesiology and Perioperative Medicine, the Second Hospital of Anhui Medical University, Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China.; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Zambelli VO; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA.; Laboratory of Pain and Signaling, Butantan Institute, Sāo Paulo, Brazil., Sinharoy P; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Brabenec L; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany., Bian Y; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Rwere F; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Hell RC; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Stein Neto B; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA.; Laboratory of Pain and Signaling, Butantan Institute, Sāo Paulo, Brazil., Hung B; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Yu X; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Zhao M; Department of Pathology.; Stanford Diabetes Research Center, and.; Stanford Cardiovascular Institute, School of Medicine, Stanford University, Stanford, California, USA., Luo Z; Department of Anesthesiology and Perioperative Medicine, the Second Hospital of Anhui Medical University, Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Wu C; Department of Anesthesiology and Perioperative Medicine, the Second Hospital of Anhui Medical University, Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Xu L; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Svensson KJ; Department of Pathology.; Stanford Diabetes Research Center, and.; Stanford Cardiovascular Institute, School of Medicine, Stanford University, Stanford, California, USA., McAllister SL; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA.; Department of Obstetrics and Gynecology, School of Medicine, Emory University, Atlanta, Georgia, USA., Stary CM; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA., Wagner NM; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany., Zhang Y; Department of Anesthesiology and Perioperative Medicine, the Second Hospital of Anhui Medical University, Key Laboratory of Anesthesiology and Perioperative Medicine of Anhui Higher Education Institutes, Anhui Medical University, Hefei, China., Gross ER; Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, California, USA.; Stanford Diabetes Research Center, and.; Stanford Cardiovascular Institute, School of Medicine, Stanford University, Stanford, California, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2023 Feb 01; Vol. 133 (3). Date of Electronic Publication: 2023 Feb 01.