Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens.

Autor: Crespi, Charles L., W-Penman, Bruce, Steimel, Dorothy T., Smith, Theresa, Yang, Chung S., Sutter, Thomas R.

Publikováno v: Mutagenesis; Mar1997, Vol. 12 Issue 2, p83-89, 7p

Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374.

Autor: Crespi, Charles L., Steimel, Dorothy T., Penman, Bruce W., Korzekwa, Kenneth R., Fernandez-Salguero, Pedro, Buters, Jeroen T.m., Gelboin, Harry V., Gonzalez, Frank J., Idle, Jeffrey R., Daly, Ann K.

Publikováno v: Pharmacogenetics; Aug1995, Vol. 5 Issue 4, p234-243, 10p

The development of a human cell line stably expressing human CYP3A4: role in the metabolic activation of aflatoxin B1 and comparison to CYP1A2 and CYP2A3.

Autor: Crespi, Charles L., Penman, Bruce W., Steimel, Dorothy T., Gelboin, Harry V., Gonzalez, Frank J.

Publikováno v: Carcinogenesis; 1991, Vol. 12 Issue 2, p355-359, 5p

Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine.

Autor: Marcucci KA; Section of Developmental Pharmacology and Experimental Therapeutics, Division of Pediatric Clinical Pharmacology and Toxicology, Children's Mercy Hospital and Clinics, Kansas City, Missouri 64108, USA., Pearce RE, Crespi C, Steimel DT, Leeder JS, Gaedigk A

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2002 May; Vol. 30 (5), pp. 595-601.