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Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a

Autor: Simons, P I H G, Valkenburg, O, Telgenkamp, I, van der Waaij, K M, de Groot, D M, Veeraiah, P, Bons, J A P, Derks, T G J, Schalkwijk, C G, Schrauwen-Hinderling, V B, Stehouwer, C D A, Brouwers, M C G J

Publikováno v: Journal of Endocrinological Investigation, 45(6), 1227-1234. Official Journal of Italian Society of Endocrinology (SIE)
Journal of endocrinological investigation, 45. SPRINGER

Purpose De novo lipogenesis has been inversely associated with serum sex hormone-binding globulin (SHBG) levels. However, the directionality of this association has remained uncertain. We, therefore, studied individuals with glycogen storage disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe00b288b7dd55180b9daa25ea74d65
https://hdl.handle.net/11370/e4e54ac3-6bb0-474f-b613-ce33d71f16a8

Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data

Autor: Pool, Rene, Hagenbeek, Fiona A., Hendriks, Anne M., van Dongen, Jenny, Willemsen, Gonneke, de Geus, Eco, van Dijk, Ko Willems, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, Harms, Amy C., Hankemeier, Thomas, Boomsma, Dorret, I, Beekman, M., Suchiman, H. E. D., Amin, N., Beulens, J. W., van der Bom, J. A., Bomer, N., Demirkan, A., van Hilten, J. A., Meessen, J. M. T. A., Pool, R., Moed, M. H., Fu, J., Onderwater, G. L. J., Rutters, F., So-Osman, C., van der Flier, W. M., van der Heijden, A. A. W. A., van der Spek, A., Asselbergs, F. W., Boersma, E., Elders, P. M., Geleijnse, J. M., Ikram, M. A., Kloppenburg, M., Meulenbelt, I, Mooijaart, S. P., Nelissen, R. G. H. H., Netea, M. G., Penninx, B. W. J. H., Stehouwer, C. D. A., Teunissen, C. E., Terwindt, G. M., 't Hart, L. M., van den Maagdenberg, A. M. J. M., van der Harst, P., van der Horst, I. C. C., van der Kallen, C. J. H., van Greevenbroek, M. M. J., van Spil, W. E., Wijmenga, C., Zwinderman, A. H., Zhernikova, A., Jukema, J. W., Wolf, J. J. H. Barkey, Cats, D., Mei, H., Slofstra, M., Swertz, M., van den Akker, E. B., Deelen, J., Reinders, M. J. T., Boomsma, D., I, van Duijn, C. M., Slagboom, P. E.

Publikováno v: Pool, R, Hagenbeek, F A, Hendriks, A M, van Dongen, J, Willemsen, G, de Geus, E, van Dijk, K W, Verhoeven, A, Suchiman, H E, Beekman, M, Slagboom, P E, Harms, A C, Hankemeier, T, Boomsma, D I, Beekman, M, Suchiman, H E D, Amin, N, Beulens, J W, van der Bom, J A, Bomer, N, Demirkan, A, van Hilten, J A, Meessen, J M T A, Pool, R, Moed, M H, Fu, J, Onderwater, G L J, Rutters, F, So-Osman, C, van der Flier, W M, van der Heijden, A A W A, van der Spek, A, Asselbergs, F W, Boersma, E, Elders, P M, Geleijnse, J M, Ikram, M A, Kloppenburg, M, Meulenbelt, I, Mooijaart, S P, Nelissen, R G H H, Netea, M G, Penninx, B W J H, Stehouwer, C D A, Teunissen, C E, Terwindt, G M, 't Hart, L M, van den Maagdenberg, A M J M, van der Harst, P, van der Horst, I C C, van der Kallen, C J H, van Greevenbroek, M M J, van Spil, W E, Wijmenga, C, Zwinderman, A H, Zhernikova, A, Jukema, J W, Wolf, J J H B, Cats, D, Mei, H, Slofstra, M, Swertz, M, van den Akker, E B, Deelen, J, Reinders, M J T, Boomsma, D I, van Duijn, C M, Slagboom, P E & BBMRI-NL Metabolomics Consortium 2020, ' Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data ', Twin Research and Human Genetics, vol. 23, no. 3, pp. 145-155 . https://doi.org/10.1017/thg.2020.53
Twin Research and Human Genetics, 23(3):1832427420000535, 145-155. Australian Academic Press
Twin research and human genetics, 23(3), 145-155. Cambridge University Press
Twin Research and Human Genetics, 23(3), 145-155. CAMBRIDGE UNIV PRESS
Twin Research and Human Genetics, 23(3), 145-155. Australian Academic Press
Pool, R, Hagenbeek, F A, Hendriks, A M, Van Dongen, J, Willemsen, G, De Geus, E, Consortium, C M, Willems Van Dijk, K, Verhoeven, A, Suchiman, H E, Beekman, M, Slagboom, P E, Harms, A C, Hankemeier, T & Boomsma, D I 2020, ' Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data ', Twin Research and Human Genetics, vol. 23, no. 3, pp. 145-155 . https://doi.org/10.1017/thg.2020.53
Twin Research and Human Genetics, 23, 3, pp. 145-155
Twin Research and Human Genetics, 23(3), 145-155. Cambridge University Press
Twin Research and Human Genetics, 23, 145-155

Metabolites are small molecules involved in cellular metabolism where they act as reaction substrates or products. The term ‘metabolomics’ refers to the comprehensive study of these molecules. The concentrations of metabolites in biological tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f13d7f35ebcb1876e9f91b2d6b8a7bf
https://hdl.handle.net/11370/b82ca290-c97f-470f-a253-e213a3cbee38