Charge carrier injection into insulating media: single-particle versus mean-field approach

Autor: Genenko, Yu. A., Yampolskii, S. V., Melzer, C., Stegmaier, K., von Seggern, H.

Publikováno v: Physical Review B 81, 125310 (2010)

Self-consistent, mean-field description of charge injection into a dielectric medium is modified to account for discreteness of charge carriers. The improved scheme includes both the Schottky barrier lowering due to the individual image charge and th

Externí odkaz: http://arxiv.org/abs/0910.4127

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Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

Autor: Montanaro, A, Kitara, S, Cerretani, E, Marchesini, M, Rompietti, C, Pagliaro, L, Gherli, A, Su, A, Minchillo, Ml, Caputi, M, Fioretzaki, R, Lorusso, B, Ross, L, Alexe, G, Masselli, E, Marozzi, M, Rizzi, Fma, La Starza, R, Mecucci, C, Xiong, Y, Jin, J, Falco, A, Knoechel, B, Aversa, F, Candini, O, Quaini, F, Sportoletti, P, Stegmaier, K, 2022 Jun 17, Roti G. Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia. Cell Death Dis., PMID: 35710782, 13(6):551. doi: 10. 1038/s41419-022-05002-5., Pmcid:, Pmc9203761.

Publikováno v: Cell deathdisease. 13(6)

Genomic studies have identified recurrent somatic alterations in genes involved in DNA methylation and post-translational histone modifications in acute lymphoblastic leukemia (ALL), suggesting new opportunities for therapeutic interventions. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd18c9246feb511fb3bbb55ca88f64c2
https://pubmed.ncbi.nlm.nih.gov/35710782

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A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma

Autor: Guenther LM, Dharia NV, Ross L, Saur Conway A, Robichaud AL, Catlett JL, Wechsler C, Frank ES, Goodale AB, Church AJ, Tseng YY, Guha R, McKnight C, Janeway KA, Boehm JS, Mora J, Davis MI, Alexe G, Piccioni F, Stegmaier K

Publikováno v: CLINICAL CANCER RESEARCH
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

PURPOSE: Novel targeted therapeutics have transformed the care of subsets of patients with cancer. In pediatric malignancies, however, with simple tumor genomes and infrequent targetable mutations, there have been few new FDA-approved targeted drugs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0e89c0c7bf876fd4c61c36ffab070477
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=15250