Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stefka B Petkova"'
Autor:
Stefka B. Petkova, Carol J. Bult, Michael A. Marion, Rong Yuan, Beverly Paigen, Shirng-Wern Tsaih, Molly A. Bogue, Gary A. Churchill, Luanne L. Peters, Kevin D. Mills, Shuqin Xing, David E. Harrison, Clifford J. Rosen, Caralina Marín de Evsikova, John P. Sundberg
Publikováno v:
Aging Cell. 8:277-287
To better characterize aging in mice, the Jackson Aging Center carried out a lifespan study of 31 genetically-diverse inbred mouse strains housed in a specific pathogen-free facility. Clinical assessments were carried out every 6 months, measuring mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8297bdee39aa275d6188fd01257cb9c8
https://doi.org/10.1111/j.1474-9726.2009.00478.x
https://doi.org/10.1111/j.1474-9726.2009.00478.x
Autor:
Stefka B. Petkova, Derry C. Roopenian, Shirng-Wern Tsaih, Rong Yuan, William H. Schott, Beverly Paigen
Publikováno v:
Physiological Genomics. 34:304-314
Inbred mouse strains are routinely used as genetically defined animal models for studying a wide assortment of biological and pathological processes, including immune system function. However, no studies have presented large-scale data on the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dadd27cd448c75c339a4a3266625835
https://doi.org/10.1152/physiolgenomics.00185.2007
https://doi.org/10.1152/physiolgenomics.00185.2007
Autor:
Stephen M. Factor, Herbert B. Tanowitz, Chris Albanese, Boumediene Bouzahzah, Stefka B. Petkova, Mahalia S. Desruisseaux, Mohan Krishnamachary, Murray Wittner, Louis M. Weiss, Fnu Nagajyothi, Richard G. Pestell, Alex W. Cohen, Shankar Mukherjee, Michael P. Lisanti, Linda A. Jelicks
Publikováno v:
Cell Cycle. 5:2396-2400
The liver is an important target of Trypanosoma cruzi infection. Infection of CD-1 mice with T. cruzi (Brazil strain) resulted in parasitism of the liver, primarily in sinusoidal and Kupffer cells. Immunoblot analysis revealed activation of extra cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742530e05b1e6fd3e425ab1b6eceb170
https://doi.org/10.4161/cc.5.20.3380
https://doi.org/10.4161/cc.5.20.3380
Autor:
Mauro M. Teixeira, David E. Gutstein, Stefka B. Petkova, Linda A. Jelicks, Herbert B. Tanowitz, Jorge L. Durand, Baiyu Tang
Publikováno v:
Magnetic Resonance Imaging. 24:1051-1057
We report on the use of centerline analysis of cardiac-gated magnetic resonance images to measure wall motion abnormalities in mice infected with Trypanosoma cruzi. To our knowledge, this is the first report of segmental wall motion abnormalities in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0bbada185610c1bbef0ec5681e22c0
https://doi.org/10.1016/j.mri.2006.04.001
https://doi.org/10.1016/j.mri.2006.04.001
Autor:
Gregory J. Christianson, Leonard G. Presta, Stefka B. Petkova, Shreeram Akilesh, Derry C. Roopenian, Thomas J. Sproule, Aaron C. Brown, Hana Al Khabbaz, Y. Gloria Meng
Publikováno v:
International Immunology. 18:1759-1769
The MHC class I-like Fc receptor FcRn plays an essential role in extending the half-life (t(1/2)) of IgG antibodies and IgG-Fc-based therapeutics in the circulation. The goal of this study was to analyze the effect of human IgG1 (hIgG1) antibodies wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18035c79f988fe351fa344781ba8142
https://doi.org/10.1093/intimm/dxl110
https://doi.org/10.1093/intimm/dxl110
Autor:
Bonnie L. Lyons, Stefka B. Petkova, Konstantin N. Konstantinov, Thomas J. Sproule, Moheeb Al Awwami, Derry C. Roopenian
Publikováno v:
The Journal of Experimental Medicine
Rheumatoid arthritis (RA) is a complex autoimmune disease with a poorly understood pathogenesis. The disease is associated with polyclonal B cell activation and the production of autoantibodies (autoAbs), but there is a longstanding controversy as to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ad6dc75dd5a023e92629100decad84
https://doi.org/10.1084/jem.20051951
https://doi.org/10.1084/jem.20051951
Autor:
Stefka B. Petkova, Joan W. Berman, Herbert B. Tanowitz, Murray Wittner, Huan Huang, Vicki L. Braunstein, Richard G. Pestell, Michael P. Lisanti, Shankar Mukherjee, Chris Albanese, George J. Christ, Louis M. Weiss
Publikováno v:
Infection and Immunity. 72:5274-5282
Trypanosoma cruzi infection causes cardiomyopathy and vasculopathy. We examined the consequence of this infection for the mitogen-activated protein kinase (MAPK) pathways, which regulate cell proliferation in cultured human umbilical vein endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe72f3575985526d09073e3700d8429b
https://doi.org/10.1128/iai.72.9.5274-5282.2004
https://doi.org/10.1128/iai.72.9.5274-5282.2004
Autor:
Thomas J. Sproule, Daniel J. Shaffer, Gregory J. Christianson, Stefka B. Petkova, Shreeram Akilesh, Derry C. Roopenian
Publikováno v:
Journal of Clinical Investigation. 113:1328-1333
The MHC class I family-like Fc receptor, FcRn, is normally responsible for extending the life span of serum IgG Ab's, but whether this molecule contributes to autoimmune pathogenesis remains speculative. To determine directly whether this function co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e0001c87adaaa7e68fedf29f021f7f
https://doi.org/10.1172/jci200418838
https://doi.org/10.1172/jci200418838
Autor:
Peter A. Eden, Derry C. Roopenian, Nadja Jung, Gregory J. Christianson, Clark L. Anderson, Thomas J. Sproule, Aaron C. Brown, Lia Avanessian, Shreeram Akilesh, Eun Young Choi, Daniel J. Shaffer, Stefka B. Petkova
Publikováno v:
The Journal of Immunology. 170:3528-3533
Abs of the IgG isotype are efficiently transported from mother to neonate and have an extended serum t1/2 compared with Abs of other isotypes. Circumstantial evidence suggests that the MHC class I-related protein, the neonatal FcR (FcRn), is the FcR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b32ca6a3c9070b2749444c2625ef1bf
https://doi.org/10.4049/jimmunol.170.7.3528
https://doi.org/10.4049/jimmunol.170.7.3528
Autor:
Stephen M. Factor, Huan Huang, Stefka B. Petkova, Pedro D'Orléans-Juste, Baiyu Tang, Madluhika Chandra, Stephen A. Douglas, Vitaliy Shtutin, Murray Wittner, Herbert B. Tanowitz, Linda A. Jelicks, Louis M. Weiss, George J. Christ, Jamshid Shirani
Publikováno v:
Clinical Science. 103:267S-271S
Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, is an important cause of cardiomyopathy. Microvascular spasm and matrix dissolution, modulated by endothelin-1 (ET-1), is implicated in the pathogenesis of chagasic heart disease. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f3a917c6e764e535327fafff0346b2
https://doi.org/10.1042/cs103s267s
https://doi.org/10.1042/cs103s267s