Výsledky vyhledávání - "Steffy W M Jansen"

Akademický článek

Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes.

Autor: Sabrina van der Kroef, Raymond Noordam, Joris Deelen, Abimbola A Akintola, Steffy W M Jansen, Iris Postmus, Carolien A Wijsman, Marian Beekman, Simon P Mooijaart, P Eline Slagboom, Diana van Heemst

Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0149992 (2016)

The rs7903146-T allele in the transcription factor 7-like 2 (TCF7L2) gene has been associated with impaired pancreatic insulin secretion, enhanced liver glucose production, and an increased risk of type 2 diabetes. Nevertheless, the impact of rs79031

Externí odkaz: https://doaj.org/article/962c4cad831a4a1cab9a6877e43f0bc7

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Akademický článek

Familial longevity is marked by lower diurnal salivary cortisol levels: the Leiden Longevity Study.

Autor: Raymond Noordam, Steffy W M Jansen, Abimbola A Akintola, Nicole Y L Oei, Andrea B Maier, Hanno Pijl, P Eline Slagboom, Rudi G J Westendorp, Jeroen van der Grond, Anton J M de Craen, Diana van Heemst, Leiden Longevity Study group

Publikováno v: PLoS ONE, Vol 7, Iss 2, p e31166 (2012)

BackgroundReported findings are inconsistent whether hypothalamic-pituitary-adrenal (HPA) signaling becomes hyperactive with increasing age, resulting in increasing levels of cortisol. Our previous research strongly suggests that offspring from long-

Externí odkaz: https://doaj.org/article/e56897d82e5a489f8bbe46aca4256e8e

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Atypical presentation of COVID-19 in older patients is associated with frailty but not with adverse outcomes

Publikováno v: European geriatric medicine. Elsevier Masson
European Geriatric Medicine, 14(2), 333-343. Elsevier Masson

Purpose: Older patients with COVID-19 can present with atypical complaints, such as falls or delirium. In other diseases, such an atypical presentation is associated with worse clinical outcomes. However, it is not known whether this extends to COVID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd1299c5b6515cb059d4a29ccb60c8b
https://doi.org/10.1007/s41999-022-00736-z

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Delirium in older COVID-19 patients: Evaluating risk factors and outcomes

Publikováno v: International Journal of Geriatric Psychiatry, 37(10):GPS5810. John Wiley & Sons Ltd.
International Journal of Geriatric Psychiatry, 37(10). Wiley
International journal of geriatric psychiatry, 37(10):GPS5810. John Wiley and Sons Ltd

OBJECTIVES: A high incidence of delirium has been reported in older patients with Coronavirus disease 2019 (COVID-19). We aimed to identify determinants of delirium, including the Clinical Frailty Scale, in hospitalized older patients with COVID-19.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d05d7db2e0a743818aeaf6b9e246d2e
https://pure.eur.nl/en/publications/056c714b-f982-4c14-8e6e-d25e40120a01

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Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study

Publikováno v: Age and Ageing, 51(3). OXFORD UNIV PRESS
Age and ageing, 51(3):afac048. Oxford University Press
Age and Ageing, 51(3):afac048. Oxford University Press

Background as the coronavirus disease of 2019 (COVID-19) pandemic progressed diagnostics and treatment changed. Objective to investigate differences in characteristics, disease presentation and outcomes of older hospitalised COVID-19 patients between

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c12d37e6776b7812a56e0552ee51da
http://hdl.handle.net/1887/3303605

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High adiposity is associated with higher nocturnal and diurnal glycaemia, but not with glycemic variability in older individuals without diabetes

Autor: Raymond Noordam, Neline C. Huurman, Carolien A. Wijsman, Abimbola A. Akintola, Steffy W. M. Jansen, Stephanie Stassen, Marian Beekman, Ondine van de Rest, P. Eline Slagboom, Simon P. Mooijaart, Diana van Heemst

Publikováno v: Frontiers in Endocrinology, 9
Frontiers in Endocrinology 9 (2018)
Frontiers in Endocrinology, Vol 9 (2018)
Frontiers in Endocrinology

Background: It is well known that adiposity is a risk factor for insulin resistance and type 2 diabetes mellitus. In the present study, we aimed to investigate the associations of measures of adiposity with indices of glycemia and of glycemic variabi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de074442fc69c71afc3b22bfa5596f48
https://doi.org/10.3389/fendo.2018.00238

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High Liver Enzyme Concentrations are Associated with Higher Glycemia, but not with Glycemia Variability, in Individuals without Diabetes Mellitus

Autor: Raymond Noordam, Debbie Vermond, Hermijntje Drenth, Carolien A. Wijman, Abimbola A. Akintola, Sabrina van der Kroef, Steffy W. M. Jansen, Neline C. Huurman, Bianca A. M. Schutte, Marian Beekman, P. Eline Slagboom, Simon P. Mooijaart, Diana van Heemst

Publikováno v: Frontiers in Endocrinology
Frontiers in Endocrinology, 8
Frontiers in Endocrinology, Vol 8 (2017)

Background Elevated concentrations of liver enzymes have been associated with an increased risk of developing type 2 diabetes mellitus. However, it remains unclear to which specific aspects of diurnal glucose metabolism these associate most. We aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969ba013ace9f53098cd4d9ca99fe61b
https://hdl.handle.net/1887/115006

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