Zobrazeno 1 - 10
of 480
pro vyhledávání: '"Steffi Oesterreich"'
Autor:
Steffi Oesterreich, Leigh Pate, Adrian V. Lee, Fangyuan Chen, Rachel C. Jankowitz, Rita Mukhtar, Otto Metzger, Matthew J. Sikora, Christopher I. Li, Christos Sotiriou, Osama S. Shah, Thijs Koorman, Gary Ulaner, Jorge S. Reis-Filho, Nancy M. Davidson, Karen Van Baelen, Laurie Hutcheson, Siobhan Freeney, Flora Migyanka, Claire Turner, Patrick Derksen, Todd Bear, Christine Desmedt
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is needed to ensure translation of findings into management and treatment guidelines. We c
Externí odkaz:
https://doaj.org/article/674206de519c4c9a91765a34839d5098
Autor:
Higinio Dopeso, Andrea M. Gazzo, Fatemeh Derakhshan, David N. Brown, Pier Selenica, Sahar Jalali, Arnaud Da Cruz Paula, Antonio Marra, Edaise M. da Silva, Thais Basili, Laxmi Gusain, Lorraine Colon-Cartagena, Shirin Issa Bhaloo, Hunter Green, Chad Vanderbilt, Steffi Oesterreich, Anne Grabenstetter, M. Gabriela Kuba, Dara Ross, Dilip Giri, Hannah Y. Wen, Hong Zhang, Edi Brogi, Britta Weigelt, Fresia Pareja, Jorge S. Reis-Filho
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract CDH1 (E-cadherin) bi-allelic inactivation is the hallmark alteration of breast invasive lobular carcinoma (ILC), resulting in its discohesive phenotype. A subset of ILCs, however, lack CDH1 genetic/epigenetic inactivation, and their genetic
Externí odkaz:
https://doaj.org/article/2bcd7e3ff5014c2e98a7bf5bd912578b
Autor:
Susrutha Puthanmadhom Narayanan, Dianxu Ren, Steffi Oesterreich, Adrian V. Lee, Margaret Q. Rosenzweig, Adam M. Brufsky
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-5 (2023)
Abstract Race and socioeconomic factors affect outcomes in breast cancer. We aimed to assess the effect of race and neighborhood socioeconomic status (SES) on overall survival and treatment patterns in patients with metastatic breast cancer (MBC). Th
Externí odkaz:
https://doaj.org/article/ad3fcd70e341405ca21a15dad541cf02
Autor:
Douglas V. Faget, Xianmin Luo, Matthew J. Inkman, Qihao Ren, Xinming Su, Kai Ding, Michael R. Waters, Ganesh Kumar Raut, Gaurav Pandey, Paarth B. Dodhiawala, Renata Ramalho-Oliveira, Jiayu Ye, Thomas Cole, Bhavna Murali, Alexander Zheleznyak, Monica Shokeen, Kurt R. Weiss, Joseph B. Monahan, Carl J. DeSelm, Adrian V. Lee, Steffi Oesterreich, Katherine N. Weilbaecher, Jin Zhang, David G. DeNardo, Sheila A. Stewart
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100534- (2024)
Externí odkaz:
https://doaj.org/article/68141490621946f3a9066df6df8be2eb
Autor:
Jing Yu, Edaise M. da Silva, Hae-Sun La, Beth Z. Clark, Jeffrey L. Fine, Gloria J. Carter, Tatiana M. Villatoro, T. Rinda Soong, Adrian V. Lee, Steffi Oesterreich, Thais Basili, Juan Blanco-Heredia, Pier Selenica, Qiqi Ye, Arnaud Da Cruz Paula, Higinio Dopeso, Andrea Gazzo, Antonio Marra, Fresia Pareja, Jorge S. Reis-Filho, Rohit Bhargava
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract This study describes “lobular-like invasive mammary carcinomas” (LLIMCas), a group of low- to intermediate-grade invasive mammary carcinomas with discohesive, diffusely infiltrative cells showing retained circumferential membranous immun
Externí odkaz:
https://doaj.org/article/a2ffe8ff28f6494d9753ae713d6f5f51
Autor:
Jian Zou, Osama Shah, Yu-Chiao Chiu, Tianzhou Ma, Jennifer M Atkinson, Steffi Oesterreich, Adrian V Lee, George C Tseng
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011754 (2024)
Cancer models are instrumental as a substitute for human studies and to expedite basic, translational, and clinical cancer research. For a given cancer type, a wide selection of models, such as cell lines, patient-derived xenografts, organoids and ge
Externí odkaz:
https://doaj.org/article/d6056c710d1441368e8499b836e820b4
Autor:
Geoffrey Pecar, Simeng Liu, Jagmohan Hooda, Jennifer M. Atkinson, Steffi Oesterreich, Adrian V. Lee
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract RET, a single-pass receptor tyrosine kinase encoded on human chromosome 10, is well known to the field of developmental biology for its role in the ontogenesis of the central and enteric nervous systems and the kidney. In adults, RET alterat
Externí odkaz:
https://doaj.org/article/63fb5f99de204429853b78720610f235
Autor:
Smruthy Sivakumar, Dexter X. Jin, Hanna Tukachinsky, Karthikeyan Murugesan, Kimberly McGregor, Natalie Danziger, Dean Pavlick, Ole Gjoerup, Jeffrey S. Ross, Robert Harmon, Jon Chung, Brennan Decker, Lucas Dennis, Garrett M. Frampton, Luciana Molinero, Steffi Oesterreich, Jeffrey M. Venstrom, Geoffrey R. Oxnard, Priti S. Hegde, Ethan S. Sokol
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Liquid biopsies could be valuable tools to monitor breast cancer progression and evolution. Here, the authors investigate genomic profiling of tissue and liquid biopsies in a large cohort of patients with breast cancer during the course of therapy to
Externí odkaz:
https://doaj.org/article/b3aeff304c474e6c83d5647b3e086870
Autor:
Hillary Stires, Igor Bado, Thelma Brown, Martha Carlson, Isaac S. Chan, Gloria V. Echeverria, Andrew J. Ewald, Bora Lim, Carla Lloyd, Julia Maues, Steffi Oesterreich, Robert N. Riter, Kelly Shanahan, Alana L. Welm, Josh Newby
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-5 (2022)
Abstract Including patient advocates in basic cancer research ensures that breast cancer research is intentional, supports effective communication with broader audiences, and directly connects researchers with those who they are striving to help. Des
Externí odkaz:
https://doaj.org/article/f2333b9b76f7493082dff1a374d8ec46
Autor:
Zheqi Li, Nicole S. Spoelstra, Matthew J. Sikora, Sharon B. Sams, Anthony Elias, Jennifer K. Richer, Adrian V. Lee, Steffi Oesterreich
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Both TP53 and ESR1 mutations occur frequently in estrogen receptor positive (ER+) metastatic breast cancers (MBC) and their distinct roles in breast cancer tumorigenesis and progression are well appreciated. Recent clinical studies discovere
Externí odkaz:
https://doaj.org/article/03cb6e6b73364a1baa4c00765d7de9ff