Persistent T-Cell Reactivity in a Seronegative Patient after SARS-CoV-2 Infection and One Vaccination

Autor: Nico Andreas, Sebastian Weis, Steffi Kolanos, Sabine Baumgart, Thomas Kamradt, Mathias W. Pletz

Publikováno v: Vaccines, Vol 10, Iss 1, p 114 (2022)

We present here a 64-year-old male participant of the CoNAN study who experienced a PCR-confirmed mild SARS-CoV-2 infection but did not develop any measurable antibody response. Additionally, after vaccination with ChAdOx1 (AstraZeneca, Cambridge, UK

Externí odkaz: https://doaj.org/article/2cd58dac4ab04c079baf68b5284fad6f

Cytokine Hemoadsorption During Cardiac Surgery Versus Standard Surgical Care for Infective Endocarditis (REMOVE): Results From a Multicenter Randomized Controlled Trial

Autor: Mahmoud Diab, Thomas Lehmann, Wolfgang Bothe, Payam Akhyari, Stephanie Platzer, Daniel Wendt, Antje-Christin Deppe, Justus Strauch, Stefan Hagel, Albrecht Günther, Gloria Faerber, Christoph Sponholz, Marcus Franz, André Scherag, Ilia Velichkov, Miriam Silaschi, Jens Fassl, Britt Hofmann, Sven Lehmann, Rene Schramm, Georg Fritz, Gabor Szabo, Thorsten Wahlers, Klaus Matschke, Artur Lichtenberg, Mathias W. Pletz, Jan F. Gummert, Friedhelm Beyersdorf, Christian Hagl, Michael A. Borger, Michael Bauer, Frank M. Brunkhorst, Torsten Doenst, Jan F Gummert, Isabella Schiller, Marcus Winter, Cornelia Eichhorn, Aicko Helbig, Florian Rißner, Kubanychbek Abdyvasiev, Alexandros Moschovas, Sebastian Freiburger, Rauf Safarov, Steffen Bargenda, Hristo Kirov, Markus Richter, Tim Sandhaus, Natig Zeynalov, Mirko Kaluza, Denis Bösemann, Swen Boog, Romanus Ostermann, P. Christian Schulze, Ali Hamadanchi, Rita Musleh, Otto W. Witte, Petra Bloos, Katrin Schwope, Steffi Kolanos, Karina Knuhr-Kohlberg, Anja Haucke, Katja Lehmann-Pohl, Carolyn Weber, Amila Cizmic, Corinna Grathwohl, Dirk Sindhu, Markus Schaschek, Axel Baier, Sebastian Schaub, Uwe Großkurth, Eranya Sone Herré, Andrey Vlasov, Dimitry Podanev, Tobias Plettenberg, Thomas Mühlbauer, Irawati Tunggal, Madlen Eichler, Jasmina Cosic, Vera Wolf, Petra Krause, Stephanie Krischer, Matthias Thielmann, Ingo Wiese, Tobias Hillmer, Jörg von Manstein, Markus Deus, Dusko Ljesic, Daniel Roloff, Tim Alabowicz Wolfgang Ristau, Gina Spangel, Johannes Kroll, Fatos Ballazhi, Stoyan Kondov, Matthias Siepe, Bartosz Rylski, Johannes Scheumann, Matthias D’Inka, Matthias Eschenhagen, Yasir Al-Hamami, Nils Bauer, Martin Thoma, Albena Rambach, Christian Ziemann, Gustavo Fernandez Baca Garcia, Julia Morlock, Christoph Benk, Alina Klink, Christoph Maltes, Gabriele Lechner, Veronika Blümel, Ulrike Heizmann, Priscilla Kotzjan, Peter Haldenwang, Mahmoud Elghannam, Dritan Useini, Dirk Buchwald, Bärbel Buchwald, Thomas Schröter, Christian Binner, Philipp Hartung, David Holzhey, Martin Misfeld, Christian Etz, Piroze Davierwala, Sergey Leontyev, Bettina Pfannmüller, Jens Garbade, Konstantin von Aspern, Diyar Saeed, Muhammed Aydin, Jonathan Herzfeld, Stefan Feder, Philipp Kiefer, Anna Meyer, Joerg Seeburger, Philipp Münch, Jörg Prehl, René Ginther, Josephine Koch, Salome Hecht, Hannes Winkler, Berit Fritzsche, Johann Winata, Julia Schmidt, Jakob Labus, Isabell Frei, Volker Schmidt, Katrin Plötze, Susanne Schal, Moritz Immohr, Yukiharu Sugimura, Anne Gietmann, Andreas Simm, Florian Höpfner, Markus Stiller, Kathrin Ludwig, Sven Helms, Jakub Sunavsky, Julia Götte, Markus Rudloff, Andrea Schönbrodt, Swetlana Fink, Ina-Maria Albrecht, Alice Huguette Minko Nnanga, Carola Schneider, Heike Schilling, Tanja Maier, Ralf-Uwe Kühnel, Stelios Ioannou, Anna-Maria Necaev, Torsten Müller, Ralph Bienek, Hendrik Treede, Zaki Kohistani, Touraj Ahmadpour, Sonja Friese, Andreas Oberbach, Maximilian Luehr, Dominik Joskowiak, Joscha Büch

Publikováno v: Circulation. 145(13)

Background: Cardiac surgery often represents the only treatment option in patients with infective endocarditis (IE). However, IE surgery may lead to a sudden release of inflammatory mediators, which is associated with postoperative organ dysfunction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3486763560dee396e630e5296a19fc5b
https://pubmed.ncbi.nlm.nih.gov/35213213

Seroprevalence of SARS-CoV-2 antibodies in an entirely PCR-sampled and quarantined community after a COVID-19 outbreak - the CoNAN study

Autor: Juliane Ankert, Bettina Loeffler, Stefan Gloeckner, Christina Bahrs, Joel Guerra, Thomas Kamradt, Michael Kiehntopf, H Proquittè, André Scherag, Mathias W. Pletz, Sebastian Weis, Stefan Hagel, Steffi Kolanos, Michael Baier, Oliwia Makarewicz, Aurelia Kimmig

BackgroundDue to the substantial proportion of asymptomatic and mild courses many SARS-CoV-2 infections remain unreported. Therefore, assessment of seroprevalence may detect the real burden of disease. We aimed at determining and characterizing the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308e1ace481d0a00f11bbb0fe723174b
https://doi.org/10.1101/2020.07.15.20154112

Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19

Autor: Angus, Derek, Derde, Lennie, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen, Beane, Abigail, van Bentum-Puijk, Wilma, Berry, Lindsay, Bhimani, Zahra, Bonten, Marc, Bradbury, Charlotte, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Cheng, Allen, de Jong, Menno, Detry, Michelle, Estcourt, Lise, Fitzgerald, Mark, Goossens, Herman, Green, Cameron, Haniffa, Rashan, Higgins, Alisa, Horvat, Christopher, Hullegie, Sebastiaan, Kruger, Peter, Lamontagne, Francois, Lawler, Patrick, Linstrum, Kelsey, Litton, Edward, Lorenzi, Elizabeth, Marshall, John, Mcauley, Daniel, Mcglothin, Anna, Mcguinness, Shay, Mcverry, Bryan, Montgomery, Stephanie, Mouncey, Paul, Murthy, Srinivas, Nichol, Alistair, Parke, Rachael, Parker, Jane, Rowan, Kathryn, Sanil, Ashish, Santos, Marlene, Saunders, Christina, Seymour, Christopher, Turner, Anne, van de Veerdonk, Frank, Venkatesh, Balasubramanian, Zarychanski, Ryan, Berry, Scott, Lewis, Roger, Mcarthur, Colin, Webb, Steven, Gordon, Anthony

Publikováno v: JAMA
JAMA Cardiology
JAMA Cardiology, 2020, 324 (13), pp.1317. ⟨10.1001/jama.2020.17022⟩

Importance Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants An ongoing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::70811ef5b6a7cc9b3a4ba92b0880250c
http://hdl.handle.net/10044/1/82224