Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Steffen Runz"'
Autor:
Peter Altevogt, Jalid Sehouli, Glen Kristiansen, Sascha Keller, Christian Rupp, Alexander Stoeck, Dominique Koensgen, Alexander Mustea, Steffen Runz, Yasmin Issa
Publikováno v:
Gynecologic Oncology. 107:563-571
Objective. CD24 is an established marker for poor prognosis in ovarian and other carcinomas. Acquisition of cytoplasmic CD24, as opposed to membranous expression, has been correlated with a higher invasiveness of tumor cells. Exosomes are small vesic
Autor:
Christian Rupp, Sascha Keller, Peter Altevogt, S. Lugert, H.-D. Hager, Steffen Runz, Mina Fogel, Alexander Stoeck, Paul Gutwein, Mohamed S. Abdel-Bakky
Publikováno v:
Kidney International. 72:1095-1102
Exosomes are small membrane vesicles that are secreted from a variety of cell types into various body fluids including the blood and urine. These vesicles are thought to play a role in cell-cell interactions. CD24 is a small but extensively glycosyla
Publikováno v:
Biochemical and biophysical research communications. 365(1)
The expression of the glycosyl phosphatidylinositol (GPI)-anchored protein CD24 correlates with poor prognosis in a variety of carcinomas. However, little is known about the cellular mechanisms of the CD24-mediated effects. In this study, we present
Publikováno v:
Journal of cell science. 119(Pt 2)
CD24 is a small, heavily glycosylated cell-surface protein which is linked to the membrane via a glycosyl-phosphatidylinositol (GPI-) anchor and therefore localizes in lipid rafts. CD24 is widely used as a cell-lineage marker for hematopoietic cells.
Autor:
Svenja Riedle, Andreas Ludwig, Peter Altevogt, François Le Naour, Steffen Runz, Paul Gutwein, Michael P. Sanderson, Sascha Keller, Eric Rubinstein, Alexander Stoeck
Publikováno v:
The Biochemical journal. 393(Pt 3)
Ectodomain shedding is a proteolytic mechanism by which transmembrane molecules are converted into a soluble form. Cleavage is mediated by metalloproteases and proceeds in a constitutive or inducible fashion. Although believed to be a cell-surface ev
Autor:
Minh-Chau Phong, Peter Altevogt, Alexander Stoeck, Otwin Linderkamp, Alexander Marmé, Paul Gutwein, Steffen Runz, Svenja Riedle, Daniela Gast, Alexander Skorokhod, Thomas P. Condon
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(7)
Purpose: The L1 adhesion molecule (CD171) is overexpressed in human ovarian and endometrial carcinomas and is associated with bad prognosis. Although expressed as a transmembrane molecule, L1 is released from carcinoma cells in a soluble form. Solubl
Autor:
Erik M. Jorgensen, Steffen Runz, Dawn Signor Matthies, Kimberly R Schuske, Janet E. Richmond, Warren S. Davis, Alexander M. van der Bliek, Daniel A. Rube
Publikováno v:
Neuron. (4):749-762
Endophilin is a membrane-associated protein required for endocytosis of synaptic vesicles. Two models have been proposed for endophilin: that it alters lipid composition in order to shape membranes during endocytosis, or that it binds the polyphospho
Publikováno v:
ResearcherID
The malignancy of a tumor depends on the capability of cancer cells to metastasize. The process of metastasis involves cell invasion through connective tissue and transmigration through endothelial monolayers. The GPI-anchored receptor CD24 expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc94c405c872a3c0cffed7a2fd7f5a1c
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000306288605159&KeyUID=WOS:000306288605159
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000306288605159&KeyUID=WOS:000306288605159
Autor:
Peter Altevogt, Steffen Runz, Celso A. Reis, Catarina Brito, Alexander Stoeck, Cristina Escrevente, Júlia Costa, Eda Machado, Alexander Marmé
Publikováno v:
Scopus-Elsevier
CIÊNCIAVITAE
CIÊNCIAVITAE
Ovarian carcinoma is the leading cause of death from gynecological cancers in many countries. Fucosylated glycoconjugates have been associated with various carcinomas. In the present study, we have characterized the expression of alpha3/4 fucosyltran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a676bdd18865ff93692ff5b2ee90631
http://www.scopus.com/inward/record.url?eid=2-s2.0-33749360659&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-33749360659&partnerID=MN8TOARS