Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Steffen Rulands"'
Autor:
Marc Jan Bonder, Stephen J. Clark, Felix Krueger, Siyuan Luo, João Agostinho de Sousa, Aida M. Hashtroud, Thomas M. Stubbs, Anne-Katrien Stark, Steffen Rulands, Oliver Stegle, Wolf Reik, Ferdinand von Meyenn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Ageing is the accumulation of changes and decline of function of organisms over time. The concept and biomarkers of biological age have been established, notably DNA methylation-based clocks. The emergence of single-cell DNA methylation prof
Externí odkaz:
https://doaj.org/article/ad7a8eed3efe49fdb4a325112b626eb9
Autor:
Nicole Cudak, Alejandra Cristina López-Delgado, Fabian Rost, Thomas Kurth, Mathias Lesche, Susanne Reinhardt, Andreas Dahl, Steffen Rulands, Franziska Knopf
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108841- (2024)
Summary: Zebrafish regenerate their fins which involves a component of cell plasticity. It is currently unclear how regenerate cells divide labor to allow for appropriate growth and patterning. Here, we studied lineage relationships of fluorescence-a
Externí odkaz:
https://doaj.org/article/ec870375f4364e47879c4f9ef08c7859
Autor:
Yiteng Dang, Steffen Rulands
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lineage tracing experiments give dynamic information on the functional behaviour of dividing cells. These experiments therefore have become an important tool for studying stem and progenitor cell fate behavior in vivo. When cell proliferation is high
Externí odkaz:
https://doaj.org/article/45af0ebf0d6f4de9941bca053babfbc6
Autor:
Mariaceleste Aragona, Sophie Dekoninck, Steffen Rulands, Sandrine Lenglez, Guilhem Mascré, Benjamin D. Simons, Cédric Blanpain
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Wound healing is essential to repair the skin after injury and distinct stem cells in the epidermis are known to contribute to the process. Here the authors perform molecular, functional and clonal analysis and reveal the individual contribution of s
Externí odkaz:
https://doaj.org/article/779059b3d15647a78f5dc85793272a21
Autor:
Samira Chabab, Fabienne Lescroart, Steffen Rulands, Navrita Mathiah, Benjamin D. Simons, Cédric Blanpain
Publikováno v:
Cell Reports, Vol 14, Iss 1, Pp 1-10 (2016)
The heart arises from distinct sources of cardiac progenitors that independently express Mesp1 during gastrulation. The precise number of Mesp1 progenitors that are specified during the early stage of gastrulation, and their clonal behavior during he
Externí odkaz:
https://doaj.org/article/01467132ff5c43f18ea6dcf1d3feeb67
Autor:
Julie K. Watson, Steffen Rulands, Adam C. Wilkinson, Aline Wuidart, Marielle Ousset, Alexandra Van Keymeulen, Berthold Göttgens, Cédric Blanpain, Benjamin D. Simons, Emma L. Rawlins
Publikováno v:
Cell Reports, Vol 12, Iss 1, Pp 90-101 (2015)
Epithelial lineages have been studied at cellular resolution in multiple organs that turn over rapidly. However, many epithelia, including those of the lung, liver, pancreas, and prostate, turn over slowly and may be regulated differently. We investi
Externí odkaz:
https://doaj.org/article/d82cbc7b82774bf1be593f7ad9c9e9f4
Autor:
Marc Jan Bonder, Stephen J. Clark, Felix Krueger, Siyuan Luo, João Agostinho de Sousa, Aida M. Hashtroud, Thomas M. Stubbs, Anne-Katrien Stark, Steffen Rulands, Oliver Stegle, Wolf Reik, Ferdinand von Meyenn
Ageing is the accumulation of changes and overall decline of the function of cells, organs and organisms over time. At the molecular and cellular level, the concept of biological age has been established and biomarkers of biological age have been ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed32a68303594e5d40c18bfb5708c8bf
https://doi.org/10.1101/2023.01.30.526343
https://doi.org/10.1101/2023.01.30.526343
Autor:
Vera A. van der Weijden, Maximilian Stoetzel, Beatrix Fauler, Dhanur P. Iyer, Mohammed Shahraz, David Meierhofer, Steffen Rulands, Theodore Alexandrov, Thorsten Mielke, Aydan Bulut-Karslioglu
Publikováno v:
bioRxiv
The quest to model and modulate embryonic development became a recent cornerstone of stem cell and developmental biology. Mammalian developmental timing is adjustable in vivo by preserving preimplantation embryos in a dormant state called diapause. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9b25ea5627b12b4e7816d63444b106
https://doi.org/10.1101/2022.08.22.504730
https://doi.org/10.1101/2022.08.22.504730
Autor:
Cole Trapnell, Uri Alon, Rinat Arbel-Goren, Jennifer Cable, Sabrina L. Spencer, Aaron M. Streets, Bo Wang, Jean Fan, Naomi Habib, Shalev Itzkovitz, Roser Vento-Tormo, Hernan G. Garcia, Andrew B. Stergachis, Merrit Romeike, Prisca Liberali, Arjun Raj, Noah F. Greenwald, Geethika Arekatla, Martin Guilliams, Clarice Kit Yee Hong, Allon M. Klein, Alex K. Shalek, Stephen R. Quake, Long Cai, Michael Ratz, Sarah J. Pfau, Jan Philipp Junker, Leeat Keren, Itai Yanai, Homaira Hamidzada, Michael S. Balzer, Silvia D.M. Santos, John I. Murray, Michael B. Elowitz, Jessica L. Whited, Ana Domingos, Steffen Rulands, Nan Zhang, Regan Hamel, Samantha A. Morris, Federico Gaiti, Kate E. Galloway
Publikováno v:
Annals of the New York Academy of SciencesReferences. 1506(1)
Single cell biology has the potential to elucidate many critical biological processes and diseases, from development and regeneration to cancer. Single cell analyses are uncovering the molecular diversity of cells, revealing a clearer picture of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00268665a765a657113f31e87c1963e3
https://pubmed.ncbi.nlm.nih.gov/34605044
https://pubmed.ncbi.nlm.nih.gov/34605044