Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Steffen Lüdeke"'
Publikováno v:
Chemistry, Vol 5, Iss 2, Pp 1203-1219 (2023)
While the use of l-proline-derived peptides has been proven similarly successful with respect to enantioselectivity, the physico-chemical and conformational properties of these organocatalysts are not fully compatible with transition state and interm
Externí odkaz:
https://doaj.org/article/28772b33263e4a77bf451b3537771924
Autor:
Britta Frensch, Thorsten Lechtenberg, Michel Kather, Zeynep Yunt, Martin Betschart, Bernd Kammerer, Steffen Lüdeke, Michael Müller, Jörn Piel, Robin Teufel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Rubromycin family of natural products belongs to aromatic polyketides with diverse bioactivities, but details of their biosynthesis are limited. Here, the authors report the complete in vitro reconstitution of enzymatic formation of the spiroketal mo
Externí odkaz:
https://doaj.org/article/2c66fdf660624127ac29372efbed73b9
Autor:
Lisa Schindler, Jutta Moosbauer, Daniel Schmidt, Thilo Spruss, Lukas Grätz, Steffen Lüdeke, Frank Hofheinz, Sebastian Meister, Bernd Echtenacher, Günther Bernhardt, Jens Pietzsch, Dirk Hellwig, Max Keller
Publikováno v:
Cancers, Vol 14, Iss 19, p 4922 (2022)
Overexpression of the neurotensin receptor type 1 (NTS1R), a peptide receptor located at the plasma membrane, has been reported for a variety of malignant tumors. Thus, targeting the NTS1R with 18F- or 68Ga-labeled ligands is considered a straightfor
Externí odkaz:
https://doaj.org/article/139517e712974dd69d17d12cf14861fd
Autor:
Christoph Müller, Jakob Gleixner, Maris-Johanna Tahk, Sergei Kopanchuk, Tõnis Laasfeld, Michael Weinhart, Dieter Schollmeyer, Martin U. Betschart, Steffen Lüdeke, Pierre Koch, Ago Rinken, Max Keller
Publikováno v:
Journal of Medicinal Chemistry. 65:4832-4853
Publikováno v:
Physical Chemistry Chemical Physics. 24:11791-11800
At low pH, the hyperphosphorylated intrinsically disordered protein phosvitin undergoes a conformational transition to a β-sheet accompanied by slow protein–protein assembly. Different cations modulate this process in different ways.
Enzymatic Asymmetric Reduction of Unfunctionalized C=C Bonds with Archaeal Geranylgeranyl Reductases
Autor:
Daniel Becker, Sonja-Verena Albers, Thomas Netscher, Steffen Lüdeke, Richard Cervinka, Michael Müller
Publikováno v:
Chembiochem
The asymmetric reduction of activated C=C bonds such as enones is well established for non‐enzymatic methods as well as in biocatalysis. However, the asymmetric reduction of unfunctionalized C=C bonds is mainly performed with transition metal catal
Autor:
Steffen Lüdeke, Philipp Lohner, Lara G. Stühn, Martin U. Betschart, Matthias C. Huber, Andreas Schreiber, Stefan M. Schiller
Publikováno v:
Angewandte Chemie. 134
Autor:
Jennifer N. Andexer, Uwe Beifuss, Mathias O. Senge, Claudia Muhle-Goll, Martin Ernst, Roland Pfau, Malte Brasholz, Rolf Breinbauer, Jochen Niemeyer, Steffen Lüdeke, Bernd F. Straub, Daniel B. Werz, Florian Beuerle, Norbert Schaschke, Christian Winter, Christian Mück-Lichtenfeld, Stephanie Kath-Schorr, Arun Narine, Tobias A. M. Gulder, Markus Kordes, Jörg Pietruszka, Thomas Lindel, Thomas Werner, Marvin Mantel, Burkhard Luy, Matthias Lehmann
Publikováno v:
Nachrichten aus der Chemie. 67:46-78
Autor:
Xavier Lucas, Stefan Günther, Michael Müller, Peter F. Leadlay, Matthias Häckh, Steffen Lüdeke, Marija Marolt
Publikováno v:
ChemBioChem. 20:1150-1154
Enzymes often convert both physiological and non-physiological substrates with high stereoselectivity; yet, for some enzymes, opposite product chirality is observed. A possible explanation is the existence of hidden specificities becoming apparent wh
Autor:
Lorenzo Arrico, Gennaro Pescitelli, Marcin Górecki, Mohammed Enamullah, Lorenzo Di Bari, Steffen Lüdeke, Irina Gruber, Marija Marolt, Mohammad Ariful Islam, Viktor Justus, Anne-Christine Chamayou, Christoph Janiak
Publikováno v:
Inorganic Chemistry. 57:13397-13408
Chiroptical broad-range spectral analysis extending from UV to mid-IR was employed to study a family of Co(II) N-(1-(aryl)ethyl)salicylaldiminato Schiff base complexes with pseudotetrahedral geometry associated with chirality-at-metal of the Δ/Λ ty